A5042248757- Venous Thromboembolism Diagnosis and Management
- Atrial Fibrillation Management and Outcomes
- Acute Myocardial Infarction Research
- Acute Ischemic Stroke Management
- Pulmonary Hypertension Research and Treatments
- Ultrasound in Clinical Applications
- Blood Coagulation and Thrombosis Mechanisms
- COVID-19 Clinical Research Studies
- Diagnosis and Treatment of Venous Diseases
- Adipokines, Inflammation, and Metabolic Diseases
- Cardiac Imaging and Diagnostics
- COVID-19 and healthcare impacts
- Sepsis Diagnosis and Treatment
- Central Venous Catheters and Hemodialysis
- Regulation of Appetite and Obesity
- Case Reports on Hematomas
- Cardiovascular Function and Risk Factors
- Heart Failure Treatment and Management
- Health Systems, Economic Evaluations, Quality of Life
- Chronic Obstructive Pulmonary Disease (COPD) Research
- Cardiovascular Disease and Adiposity
- Cardiovascular and Diving-Related Complications
- Protease and Inhibitor Mechanisms
- Cardiovascular Effects of Exercise
- Antiplatelet Therapy and Cardiovascular Diseases
Democritus University of Thrace
2016-2025
Johannes Gutenberg University Mainz
2016-2025
University Medical Center of the Johannes Gutenberg University Mainz
2016-2025
Klinik und Poliklinik für Psychosomatische Medizin und Psychotherapie
2015-2024
Agia Olga Hospital
2024
Brigham and Women's Hospital
2024
Harvard University
2024
Yeditepe University
2023
Charité - Universitätsmedizin Berlin
2023
Aalborg University Hospital
2022
Guidelines summarize and evaluate available evidence with the aim of assisting health professionals in proposing best management strategies for an individual patient a given condition. their recommendations should facilitate decision making daily practice. However, final decisions concerning must be made by responsible professional(s) consultation caregiver as appropriate.
The ESC Guidelines represent the views of and were produced after careful consideration scientific medical knowledge evidence available at time their publication.The is not responsible in event any contradiction, discrepancy and/or ambiguity between other official recommendations or guidelines issued by relevant public health authorities, particular relation to good use healthcare therapeutic strategies.Health professionals are encouraged take fully into account when exercising clinical...
Non-thrombotic PE does not represent a distinct clinical syndrome. It may be due to variety of embolic materials and result in wide spectrum presentations, making the diagnosis difficult. With exception severe air fat embolism, haemodynamic consequences non-thrombotic emboli are usually mild. Treatment is mostly supportive but differ according type material severity.
The role of fibrinolytic therapy in patients with intermediate-risk pulmonary embolism is controversial.In a randomized, double-blind trial, we compared tenecteplase plus heparin placebo normotensive embolism. Eligible had right ventricular dysfunction on echocardiography or computed tomography, as well myocardial injury indicated by positive test for cardiac troponin I T. primary outcome was death hemodynamic decompensation (or collapse) within 7 days after randomization. main safety...
<b>New @ESCardio Guidelines for the Diagnosis and Management of Acute #PulmonaryEmbolism developed in collaboration with @EuroRespSoc now available: #cardiotwitter @erspublications</b>http://bit.ly/2HnrJaj
The use of thrombolytic agents in the treatment hemodynamically stable patients with acute submassive pulmonary embolism remains controversial.
Background Thrombolytic treatment has been shown to accelerate resolution of major pulmonary embolism and lead a rapid improvement right-side hemodynamics. However, the association between these favorable effects clinical outcome patients who have no severe hemodynamic compromise at presentation remains unknown. Methods Results The present multicenter registry included 719 consecutive with according clinical, echocardiographic, scintigraphic, cardiac catheterization criteria. Symptom onset...
Background— Assessment of risk and appropriate management patients with acute pulmonary embolism (PE) remains a challenge. Cardiac troponins I (cTnI) T (cTnT) are reliable indicators myocardial injury may be associated right ventricular dysfunction in PE. Methods Results— The present prospective study included 106 consecutive confirmed cTnI was elevated (≥0.07 ng/mL) 43 (41%), cTnT (≥0.04 39 (37%). Elevation or significantly echocardiographically detected ( P =0.001 <0.05, respectively)....
To investigate the prognostic value of echocardiographic findings in patients who present with symptoms suggestive acute pulmonary embolism.317 clinically suspected embolism were prospectively evaluated by echocardiography for presence right ventricular afterload stress and heart or artery thrombi. Objective confirmation lung scan angiography was obtained 164 (52%). The deep venous thrombosis established 90 158 (57%) underwent phlebographic Doppler sonographic studies.Right diagnosed 87...
The surgical closure of an atrial septal defect is frequently recommended for patients over 40 years age. However, the prognosis such with unrepaired defects largely unknown, and outcome operated on after fourth decade life has not yet been compared that medically treated in a controlled follow-up study.
Right-to-left shunt through a patent foramen ovale is frequently diagnosed by contrast echocardiography and can be particularly prominent in the presence of elevated pressures right side heart. Its prognostic significance patients with pulmonary thromboembolism, however, unknown.The present prospective study included 139 consecutive major embolism on basis clinical, echocardiographic, cardiac catheterization criteria. All underwent at presentation. The end points were overall mortality...
Pulmonary embolism (PE) is the third most common cardiovascular cause of death; systemic thrombolysis potentially lifesaving treatment in patients presenting with haemodynamic instability. We investigated trends use and outcome acute PE.We analysed data on characteristics, comorbidities, treatment, in-hospital 885 806 PE Germany between 2005 2015. Incidence was 99/100 000 population/year increased from 85/100 to 109/100 2015 [β 0.32 (0.26-0.38), P < 0.001]. During same period, case fatality...
Neutrophil extracellular traps (NETs) are chromatin filaments released by activated polymorphonuclear neutrophils (PMNs) and decorated with granule proteins various properties. Several lines of evidence implicate NETs in thrombosis. The functional significance the vivo relevance during atherothrombosis humans have not been addressed until now.Selective sampling thrombotic material surrounding blood from infarct-related coronary artery (IRA) non-IRA was performed primary percutaneous...