A5091911388- Emergency and Acute Care Studies
- Cardiac Arrest and Resuscitation
- Venous Thromboembolism Diagnosis and Management
- Healthcare Systems and Practices
- Health, Medicine and Society
- Chronic Disease Management Strategies
- Trauma and Emergency Care Studies
- Thermal Regulation in Medicine
- Disaster Response and Management
- Acute Ischemic Stroke Management
- Ultrasound in Clinical Applications
- Pediatric Pain Management Techniques
- Acute Myocardial Infarction Research
- Healthcare Policy and Management
- Sepsis Diagnosis and Treatment
- HIV/AIDS Research and Interventions
- HIV, Drug Use, Sexual Risk
- Homelessness and Social Issues
- Migration, Identity, and Health
- Cardiovascular Syncope and Autonomic Disorders
- Central Venous Catheters and Hemodialysis
- COVID-19 diagnosis using AI
- Atrial Fibrillation Management and Outcomes
- Pain Management and Placebo Effect
- Traumatic Brain Injury and Neurovascular Disturbances
University Hospital of Lausanne
2016-2025
University of Lausanne
2016-2025
Xilinx (United States)
2024
University Hospital of Bern
2011-2019
Hôpital Orthopédique de la Suisse Romande
2004-2017
Wesley Research Institute
2016
Institute of Social and Preventive Medicine
2015
Creative Commons
2014
University of Geneva
2014
University Hospital of Geneva
2006-2008
Pulmonary edema results from a persistent imbalance between forces that drive water into the air space and physiologic mechanisms remove it. Among latter, absorption of liquid driven by active alveolar transepithelial sodium transport has an important role; defect this mechanism may predispose patients to pulmonary edema. Beta-adrenergic agonists up-regulate clearance fluid attenuate in animal models.
The clinical benefit of adding a macrolide to β-lactam for empirical treatment moderately severe community-acquired pneumonia remains controversial.To test noninferiority alone compared with and combination in pneumonia.Open-label, multicenter, noninferiority, randomized trial conducted from January 13, 2009, through 31, 2013, 580 immunocompetent adult patients hospitalized 6 acute care hospitals Switzerland pneumonia. Follow-up extended 90 days. Outcome assessors were masked...
The aim of this study is to compare the Hestia rule vs. simplified Pulmonary Embolism Severity Index (sPESI) for triaging patients with acute pulmonary embolism (PE) home treatment.Normotensive PE 26 hospitals from France, Belgium, Netherlands, and Switzerland were randomized either or sPESI. They designated treatment if tool was negative physician-in-charge, taking into account patient's opinion, did not consider that hospitalization required. main outcomes 30-day composite recurrent venous...
The metabolic syndrome comprises a clustering of cardiovascular risk factors but the underlying mechanism is not known. Mice with targeted disruption endothelial nitric oxide synthase (eNOS) are hypertensive and insulin resistant. We wondered, whether eNOS deficiency in mice associated phenotype mimicking human syndrome.In addition to arterial pressure sensitivity (euglycaemic hyperinsulinaemic clamp), we measured plasma concentration leptin, insulin, cholesterol, triglycerides, free fatty...
Nitric oxide (NO) plays a major role in the regulation of cardiovascular and metabolic homeostasis, as evidenced by insulin resistance arterial hypertension endothelial NO synthase (eNOS) null mice. Extrapolation these findings to humans is difficult, however, because eNOS gene deficiency has not been reported. polymorphism impaired synthesis, have reported several disease states could predispose resistance. High-fat diet induces normal To test whether partial facilitates development during...
The cause of acute exacerbation chronic obstructive pulmonary disease (COPD) is often difficult to determine. Pulmonary embolism may be a trigger dyspnoea in patients with COPD.To determine the prevalence COPD.123 consecutive admitted emergency departments two academic teaching hospitals for moderate very severe COPD were included. was investigated all (whether or not clinically suspected) following standardised algorithm based on d-dimer testing, lower-limb venous ultrasonography and...
To identify risk factors, circumstances, and outcomes for individuals with acute ischemic stroke (AIS) chameleons (AIS-C) arriving in the emergency department of a university hospital.We retrospectively reviewed all patients AIS from prospectively constructed Acute Stroke Registry Analysis Lausanne during 8.25 years. AIS-C were defined as failure to suspect or incorrect exclusion diagnosis. They compared diagnosed correctly at time admission.Forty-seven 2,200 missed (2.1%). These either very...
Priority dispatch accuracy is a key issue in optimizing the match between patients' medical needs and pre-hospital resources. This study measures of Criteria Based Dispatch (CBD) system, by evaluating discrepancies priorities ambulance crews' severity evaluations. retrospective conducted from January 2011 to December 2011. We ruled that National Advisory Committee for Aeronautics (NACA) score > 3 (injuries/diseases which can possibly lead deterioration vital signs) 7 (lethal injuries/...
Abstract Background Lung ultrasonography (LUS) is a promising pragmatic risk-stratification tool in coronavirus disease 2019 (COVID-19). This study describes and compares LUS characteristics between patients with different clinical outcomes. Methods Prospective observational of polymerase chain reaction–confirmed adults COVID-19 symptoms lower respiratory tract infection the emergency department (ED) Lausanne University Hospital. A trained physician recorded images using standardized...
Background: Recently, validated clinical decision rules have been developed that avoid unnecessary use of computed tomographic pulmonary angiography (CTPA) in patients with suspected embolism (PE) the emergency department (ED). Objective: To measure any resulting change CTPA for PE. Design: Retrospective analysis. Setting: 26 European EDs 6 countries. Patients: Patients performed PE ED during first 7 days each odd month between January 2015 and December 2019. Measurements: The primary end...
Background: Women may receive suboptimal pain management compared with men, and this disparity might be related to gender stereotypes. Objectives: To assess the influence of patient on acute low back pain. Design: We assessed by 231 physicians using an online clinical vignette describing a consultation for in female or male patient. The was followed questionnaire that physicians’ decisions their Methods: created presenting patient’s management. investigated gender-related stereotyping...
The objectives of this study were to determine the proportions psychiatric and substance use disorders suffered by emergency departments’ (EDs’) frequent users compared mainstream ED population, evaluate how effectively these diagnosed in both groups patients physicians, if predictive a services. This is cross-sectional with concurrent retrospective data collection. Between November 2009 June 2010, patients’ mental health identified prospectively face-to-face research interviews using...