A5021827999- Respiratory Support and Mechanisms
- Intensive Care Unit Cognitive Disorders
- Cardiac Arrest and Resuscitation
- Neonatal Respiratory Health Research
- Airway Management and Intubation Techniques
- Anesthesia and Sedative Agents
- Anesthesia and Neurotoxicity Research
- Liver Disease and Transplantation
- Chronic Obstructive Pulmonary Disease (COPD) Research
- Nosocomial Infections in ICU
- Thermal Regulation in Medicine
- Family and Patient Care in Intensive Care Units
- Mechanical Circulatory Support Devices
- Organ Transplantation Techniques and Outcomes
- Liver Disease Diagnosis and Treatment
- Atomic and Subatomic Physics Research
- Antibiotic Use and Resistance
- Neuroscience of respiration and sleep
- Infection Control and Ventilation
- Antifungal resistance and susceptibility
- Hepatocellular Carcinoma Treatment and Prognosis
- Obstructive Sleep Apnea Research
- Urban and Freight Transport Logistics
- Laser Applications in Dentistry and Medicine
- Tendon Structure and Treatment
Agostino Gemelli University Polyclinic
2016-2025
Istituti di Ricovero e Cura a Carattere Scientifico
2019-2025
Università Cattolica del Sacro Cuore
2010-2024
Societatea Română de Anestezie şi Terapie Intensivă
2019
Catholic University of America
2015
Positive end-expiratory pressure (PEEP) can potentially modulate inspiratory effort (ΔPes), which is the major determinant of self-inflicted lung injury.
Dexmedetomidine can be used for sedation of mechanically ventilated patients and has minor respiratory effects. The aim this study was to compare the incidence patient-ventilator dyssynchronies during with dexmedetomidine or propofol.We conducted a multicentre, prospective, open-label, randomised clinical trial, comparing standard propofol at three intensive care units university hospitals in Italy. Twenty difficult-to-wean whom first weaning trial had failed who were on pressure support...
Abstract Background (1,3)-β- d -Glucan has been widely used in clinical practice for the diagnosis of invasive Candida infections. However, such serum biomarker showed potential to guide antimicrobial therapy order reduce duration empirical antifungal treatment critically ill septic patients with suspected candidiasis. Methods This was a single-centre, randomized, open-label trial which were enrolled during admission intensive care unit (ICU). All who presented infection risk factors and...
Postoperative respiratory failure (PRF, namely mechanical ventilation >48 hours) significantly affects morbidity and mortality in liver transplantation (LTx). Previous studies analyzed only one or two categories of PRF risk factors (preoperative, intraoperative postoperative ones). The aims this study were to identify predictors, assess the length stay (LoS) ICU 90-day survival according LTx patients.Two classification approaches used: systematic (recipient-related preoperative factors;...
Background: Hepatic dysfunction (HD) after liver transplantation (LT) or extended hepatic resection (EHR) is associated with graft failure and high short-term mortality. We evaluated the safety depurative efficacy of CytoSorb® in these settings. The primary endpoint was change serum total bilirubin at end treatment compared to baseline value. secondary evaluate trend coagulation parameters up 72 h discontinuation CytoSorb®. effects therapy on degree encephalopathy (HE), Sequential Organ...
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In pediatric liver recipients perioperative factors may affect respiratory and cardiac function, prolong mechanical ventilation during post-operative period. The use of NAVA can improve the interaction between patient ventilator from both a perspective. objective this study is to evaluate synchronization ventilator, as well application neurally adjusted ventilatory assist (NAVA) pressure support (PSV) in transplant recipients. This single-center, prospective, randomized, physiological...
While proportional ventilator modes have gained popularity in adult patients' ventilatory management, Proportional Assist Ventilation (PAV+) use pediatric patients with Pediatric Acute Respiratory Distress Syndrome (PARDS) remains unexplored. This study aims to evaluate the effects of optimized PSV and PAV+ on patient-ventilator interaction respiratory pattern two simulated lung models. The utilized an active simulator replicate models: one healthy mild PARDS. Each model was ventilated using...
Background: Thromboelastography-6s (TEG®6s), a novel device developed to assess coagulation status, presents advantages such as less frequent calibration, ease of use, and greater stability against movements compared the previous system (TEG5000). This is first study in literature compare profiles early postoperative period liver resection (LR) using conventional tests (CCTs) TEG®6s. Methods: Forty-six adult patients admitted ICU post-surgery after elective LR for malignancy were included....
We investigated whether behavioral precautions adopted during Coronavirus disease (COVID-19) pandemic also influenced the spreading and multidrug resistance (MDR) of ESKAPEEc (Enterococcus faecium, Staphylococcus aureus, Klebsiella pneumoniae, Acinetobacter baumannii [AB], Pseudomonas aeruginosa, Enterobacter spp Escherichia Coli, [EC]) among Intensive Care Unit (ICU) patients.We performed a single-center retrospective study in adult patients admitted to our COVID-19-free surgical ICU. Only...
We measured noise intensity and perceived noisiness during continuous positive airway pressure (CPAP) performed with two interfaces (face-mask, helmet) four delivery systems.Eight healthy volunteers received CPAP in random order with: systems provided a flow generator using the Venturi effect mechanical expiratory valve (A: Venturi, Starmed; B: Whisperflow-2, Caradyne Ltd); one 'free-flow' system high O(2) air flowmeters, an inspiratory gas reservoir, water (C: CF800, Drägerwerk, AG);...
Complications in pediatric anesthesia can happen, even our modern hospitals with the most advanced equipment and skilled anesthesiologists. It is important, albeit a tranquil reassuring way, to inform parents of possibility complications and, general, anesthetic risks. This especially imperative when speaking children who will be operated on for minor procedures: experience, they tend think that light without Often surgeons tell them operation very simple stressing fact it done under general...
The clinical course of intensive care unit (ICU) patients may be complicated by a large spectrum lower respiratory tract infections (LRTI), defined specific epidemiological, and microbiological aspects. A European network for ICU-related (ENIRRIs), supported the Respiratory Society, has been recently established, with aim at studying all infective episodes except community-acquired ones. multicentre, observational study is in progress, enrolling more than 1000 fulfilling clinical,...
<h3>BACKGROUND:</h3> In adults and children, patient-ventilator synchrony is strongly dependent on both the ventilator settings interface used in applying positive pressure to airway. The aim of this bench study was determine whether different interfaces may influence interaction pediatric models normal mixed obstructive restrictive respiratory conditions. <h3>METHODS:</h3> A test lung, connected a mannequin using (endotracheal tube [ETT], face mask, helmet), ventilated support ventilation...
Several respiratory abnormalities can be present in primary hypothyroidism and reversed with adequate hormone treatment. However, the role of thyroid replacement therapy on system patients nonthyroidal illness syndrome is still unclear. This physiologic study evaluated effect treatment muscle function subjects while mechanical ventilation. The end point was neuromechanical efficiency, which provides an estimate efficiency diaphragmatic contraction. Secondary points were transdiaphragmatic...
To compare helmet noninvasive ventilation (NIV), in terms of patient-ventilator interaction and performance, using 2 different circuits for connection: a double tube circuit (with one inspiratory expiratory line) standard (a Y-piece connected only to side the helmet, closing other side).A manikin, test lung set at breathing frequencies (20 30 breaths/min), was ventilated pressure support (PSV) mode with settings, randomly applied, ratio pressurization time trigger (T(press)/T(exp-trigger))...