Nefise Öztoprak
A5052361973- Hepatitis C virus research
- Nosocomial Infections in ICU
- Antibiotic Use and Resistance
- Hepatitis B Virus Studies
- Antibiotic Resistance in Bacteria
- Antimicrobial Resistance in Staphylococcus
- Liver Disease Diagnosis and Treatment
- Pneumonia and Respiratory Infections
- Bacterial Identification and Susceptibility Testing
- Bacterial Infections and Vaccines
- Infectious Diseases and Tuberculosis
- Urinary Tract Infections Management
- Diabetic Foot Ulcer Assessment and Management
- Viral Infections and Vectors
- Orthopedic Infections and Treatments
- Infection Control in Healthcare
- Hepatitis Viruses Studies and Epidemiology
- Patient Satisfaction in Healthcare
- Rabies epidemiology and control
- Streptococcal Infections and Treatments
- Bacillus and Francisella bacterial research
- Osteomyelitis and Bone Disorders Research
- Antifungal resistance and susceptibility
- Enterobacteriaceae and Cronobacter Research
- Pneumocystis jirovecii pneumonia detection and treatment
Antalya Eğitim ve Araştırma Hastanesi
2012-2024
Bursa Uludağ Üni̇versi̇tesi̇
2023
Sağlık Bilimleri Üniversitesi
2019-2022
Bülent Ecevit University
2006-2021
Creative Commons
2021
Turkish Society of Cardiology
2017
Akdeniz University
2015
University Medical Center Freiburg
2015
The Royal Free Hospital
2015
University College London
2015
Initial antimicrobial therapy (AB) is an important determinant of clinical outcome in patients with severe infections as pneumonia, however well-conducted studies regarding prognostic impact inadequate initial AB who are not undergoing mechanical ventilation (MV) lacking. In this study we aimed to identify the risk factors for and determine its subsequent on outcomes both ventilator associated pneumonia (VAP) hospital acquired (HAP). We retrospectively studied accuracy a university Turkey. A...
Caspase-associated recruitment domain-9 (CARD9) deficiency is an autosomal-recessive primary immunodeficiency with genetic defects in Th17 immunity marked by susceptibility to recurrent and invasive Candida infections. We present a case of relapsing albicans meningoencephalitis over 1-year period despite appropriate antifungal therapy. detected homozygous p.Q295X mutation CARD9 as well defective interleukin-17 interferon gamma synthesis Enzyme-Linked ImmunoSpot tests. achieved complete...
BackgroundThe aim of this study was to delineate mortality indicators in pneumococcal meningitis with special emphasis on therapeutic implications.MethodsThis retrospective, multicenter cohort involved a 15-year period (1998–2012). Culture-positive cases (n = 306) were included solely from 38 centers.ResultsFifty-eight patients received ceftriaxone plus vancomycin empirically. The rest given third-generation cephalosporin alone. Overall, 246 (79.1%) isolates found be penicillin-susceptible,...
Objective: The aim of this study was to analyze the temporal trends HIV epidemiology in Turkey from 2011 2016. Method: Thirty-four teams 28 centers at 17 different cities participated retrospective study. Participating were asked complete a structured form containing questions about epidemiologic, demographic and clinical characteristics patients presented with new diagnosis between Demographic data all (complete or partial) included analyses. For cascade care analysis, 15 that provided full...
The purpose of this study was to evaluate compliance with guidelines in surgical prophylaxis (SP) procedures Turkey.A point prevalence involving 4 university, 5 education and research 7 public hospitals performed assessing for antibiotic use SP. Compliance based on the "Clinical Practice Guidelines Antimicrobial Surgery (CPGAS) 2013" guideline.Sixteen centers were included study, 166 operations at these being evaluated. Parenteral SP applied 161 (96.9%) these. Type inappropriate 66 (40.9%)...
We explored the self-reported antibiotic stewardship (AS), and infection prevention control (IPC) activities in intensive care units (ICUs) of different income settings. A cross-sectional study was conducted using an online questionnaire to collect data about IPC AS measures participating ICUs. The participants were Infectious Diseases-International Research Initiative (IDI-IR) members, committed as per their institutional agreement form. analyzed responses from 57 ICUs 24 countries...
To determine the true incidence of hGISA/GISA and its consequent clinical impact, methods must be defined that will reliably reproducibly discriminate these resistant phenotypes from vancomycin susceptible S. aureus (VSSA). This study assessed compared ability eight Dutch laboratories under blinded conditions to VSSA intra- inter-laboratory reproducibility agar screening plates Etest method. A total 25 unique strains (10 VSSA, 9 hGISA 6 GISA) were categorized by PAP-AUC method PFGE typed...
This multi-centre study aimed to determine the antibiotic consumption in Turkish hospitals by point prevalence. Antibiotic of 14 centres was determined using DDD method. Among hospitalized patients, 44.8% were antibiotics and total 674.5 DDD/1000 patient-days (DPD). 189.6 (28%) DPD restricted while 484.9 (72%) unrestricted. Carbapenems (24%) beta lactam/beta lactamase inhibitors (ampicillin-sulbactam or amoxicillin-clavulanate; 22%) most commonly used unrestricted antibiotics. Antibiotics...
Abstract Background Some of the hantavirus species in Euro‐Asia cause haemorrhagic fever with renal syndrome (HFRS) humans. The first documented human infection Turkey was diagnosed 2009. This report describes dynamics outbreak that emerged humans Western Black Sea Region Turkey. Methods All suspected cases were admitted to Infectious Diseases and Clinical Microbiology Department at Zonguldak Bülent Ecevit University Hospital Zonguldak, patients carefully interviewed, examined evaluated...
Aim: The aim of this prospective observational study was to evaluate the impact two cleaning and disinfecting methods use steam against methicillin-resistant Staphylococcus aureus, vancomycin-resistant Enterococcus faecalis, carbapenem-resistant Pseudomonas aeruginosa multidrug-resistant (MDR) Acinetobacter baumannii in a tertiary referral hospital. Methods: McFarland 0.5 suspensions (content 1.5 x 108 cfu/ml) four challenge bacterial species were prepared used inoculate different sites...