- Heart Failure Treatment and Management
- Acute Myocardial Infarction Research
- Cardiovascular Function and Risk Factors
- Inflammatory Biomarkers in Disease Prognosis
- Cardiac Fibrosis and Remodeling
- Venous Thromboembolism Diagnosis and Management
- Cardiac Imaging and Diagnostics
- Cardiovascular and Diving-Related Complications
- Infectious Diseases and Tuberculosis
- Pulmonary Hypertension Research and Treatments
- Ocular Diseases and Behçet’s Syndrome
- Diabetes Treatment and Management
- Heparin-Induced Thrombocytopenia and Thrombosis
- Amoebic Infections and Treatments
- Sleep and related disorders
- Cytomegalovirus and herpesvirus research
- Gout, Hyperuricemia, Uric Acid
- Leptospirosis research and findings
- Neutrophil, Myeloperoxidase and Oxidative Mechanisms
- Blood Coagulation and Thrombosis Mechanisms
- Systemic Sclerosis and Related Diseases
- Restless Legs Syndrome Research
Administração Regional de Saúde de Lisboa e Vale do Tejo
2025
Hospital de São João
2021-2024
Centro de Genética Clínica
2024
Universidade do Porto
2022-2024
The development of SARS-CoV-2 vaccines has raised several concerns regarding venous thromboembolism, namely cerebral thrombosis. Although thrombosis been reported after administration a viral vector vaccine, due to possible auto-immune mechanism inducing thrombocytopenia, the same not happened in mRNA vaccines. We report two cases thrombosis, shortly vaccine. In both patients, there was no evidence thrombocytopenia or antiplatelet antibodies, and alternative causes for were found. As such,...
Abstract Background: Increased levels of platelet distribution width (PDW) can predict cardiac death and infarction recurrence in acute myocardial infarction. PDW appears to be a prognosis marker heart failure (HF); however, its impact on chronic HF is still unknown. We investigated the HF. Methods: retrospectively analyzed outpatients with left ventricular systolic dysfunction (LVSD) from January 2012 May 2018. Patients no data or preserved recovered ejection fraction were excluded. The...
The prognostic implications of using benzodiazepines (BZD) in heart failure (HF) patients are still unknown.This study aimed to assess the association BZD use with all‑cause death ambulatory, chronic HF patients.We investigated a retrospective cohort ambulatory left ventricular systolic dysfunction (LVSD). were followed up from their first medical appointment until January 2021 and mortality was primary end point. Cox regression analysis used between mortality. Subgroup analyses performed...
Patients with heart failure (HF) often have multiple cardiovascular risk factors (CVRF) and comorbidities (CMB). We evaluated the impact of additive CMB CVRF in HF prognosis.
Introduction: Hyperuricemia (HU) is associated with an increased risk of incident heart failure (HF) and adverse HF outcomes. Patients diabetes mellitus (DM) have a greater prevalence HU. Aims: We evaluated the prognostic impact HU in patients according to coexistence DM. Methods: A retrospective cohort study ambulatory left ventricular systolic dysfunction (LVSD) was conducted from January 2012 May 2018. The end point all-cause mortality; follow-up until 2021. Cox regression analysis used...
Pulmonary arterial hypertension (PAH) is an increasingly recognised clinical entity that associated with connective tissue disease (CTD) in up to one quarter of all diagnoses. Sjögren's syndrome (SS) a chronic autoimmune characterised by ocular and oral dryness resulting from lacrimal salivary gland dysfunction. Additionally, SS may involve virtually any organ system and, as result, the pleomorphic manifestations. However, SS-PAH reports are scarce, area remains insufficiently studied. We...
Leptospirosis is a zoonotic infection infrequently reported in non-tropical regions. Although classically described as biphasic illness, unusual clinical manifestations have been reported, including previous case of lung abscess associated with this causative agent. We present the 49-year-old man new diagnosis two liver abscesses leptospirosis.Leptospirosis zoonosis caused by spirochetes genus Leptospira; more commonly tropical regions.Leptospirosis manifests first phase characterized high...
Uveo-meningeal syndromes are any disorder characterized by the involvement of uvea and meninges. They can have multiple causes, including infectious, autoimmune malignant diseases. We report case a patient with 10-year-old diagnosis myelodysplastic syndrome that had been stable. He presented new onset uveitis, ataxia, diplopia fluctuating consciousness level, without obvious cause revealed brain imaging or blood chemistries. An extensive aetiological search showed no cause. Initially,...