A5085145036- Cancer Diagnosis and Treatment
- Bone health and treatments
- Cardiac tumors and thrombi
- Sarcoidosis and Beryllium Toxicity Research
- Medical Imaging and Pathology Studies
- Infective Endocarditis Diagnosis and Management
- Vasculitis and related conditions
- Drug-Induced Hepatotoxicity and Protection
- MRI in cancer diagnosis
- Otolaryngology and Infectious Diseases
- Autoimmune and Inflammatory Disorders Research
- Neutrophil, Myeloperoxidase and Oxidative Mechanisms
- Venous Thromboembolism Diagnosis and Management
- Cancer-related Molecular Pathways
- Cardiac Fibrosis and Remodeling
- Acute Ischemic Stroke Management
- Bone and Joint Diseases
- IgG4-Related and Inflammatory Diseases
- Cancer Genomics and Diagnostics
- Nephrotoxicity and Medicinal Plants
- Neuroendocrine Tumor Research Advances
- Parvovirus B19 Infection Studies
- Cerebrovascular and Carotid Artery Diseases
- Foreign Body Medical Cases
- Inflammatory Bowel Disease
Hospital de São João
2022-2023
Algarve Biomedical Center
2023
Universidade do Porto
2023
Terra
2023
Malignant hypercalcemia is a common finding in patients with advanced cancer, involving mechanisms like tumor secretion of parathyroid hormone (PTH)-related protein, osteolytic metastases, and production calcitriol. Although rare, induced by ectopic tumoral PTH can be an additional mechanism. Here we present 84-year-old male patient who was admitted to the hospital non-productive cough, anorexia, single episode small-volume hemoptysis. He diagnosed stage T4N3M1c left lung small cell...
Immunoglobulin G4-related disease (IgG4-RD) is an immunomediated that can virtually affect any organ. Despite the pancreas being known as most frequently involved organ, pulmonary and pleural IgG4-RD increasingly reported. The authors present two cases of diagnosed in same year, with different presentations outcomes, which lung involvement were essential for diagnosis. Recognizing a possible cause chronic effusion and/or thickening abnormalities important early diagnosis prognosis improvement.
The diagnosis of infective endocarditis is challenging because it has a variable clinical presentation and nonspecific symptoms can present in different forms, especially when an unusual etiological agent involved. We the case female her 70s admitted to hospital with medical history bicytopenia, severe aortic stenosis, rheumatoid arthritis. She had several consultations during which she presented asthenia general malaise. A septic screen test was performed that would determine Streptococcus...
Haemophagocytic lymphohistiocytosis is a syndrome of excessive immunological activation that can be triggered by various diseases, including haematological cancers. We report case 25-year-old woman presenting with constitutional symptoms and painful thoracic mass four months duration. Laboratory exams showed pancytopenia, hypertriglyceridemia extremely high serum ferritin levels. A whole-body computed tomography (CT) scan revealed splenomegaly highlighted the on deep tissues left breast;...
Granulomatosis with polyangiitis (GPA) is a necrotizing vasculitis of small and medium vessels involvement the upper lower respiratory tract pauci-immune glomerulonephritis [1]. This has higher incidence in men sixth decade life more than 80% patients have positive anti-neutrophil cytoplasm (ANCA) antibodies [1,2]. We present case 23-year-old man two weeks evolution polyarthralgia, asthenia, cough hemoptoic sputum. He did chest radiography that showed diffuse bilateral alveolar infiltrates,...
Ehlers-Danlos Syndrome (EDS) is a group of genetic diseases the connective tissue, which rare and characterized by joint hypermobility, vascular fragility. We present case 38-year-old woman with known diagnosis EDS type VI who came to emergency room, complaining sudden dyspnea in context abdominal pain left lower limb one week evolution. Computed axial tomography showed presence bilateral pulmonary thromboembolism, iliofemoral thrombosis, retroperitoneal hematoma. Anticoagulation was started...
Gastric metastasis is an infrequent occurrence, especially when derived from lung adenocarcinomas. They can grossly resemble advanced gastric cancer and require comprehensive evaluations of the patients their symptoms. Here, we present case a 71-year-old patient admitted to our hospital due intense, cramping abdominal pain. He had been previously diagnosed with right lower lobe adenocarcinoma lung, which was treated in previous year chemotherapy radiotherapy good clinical response. The CT...
Cerebral Small vessel disease (SVD) is a disorder of the cerebral microvessels and commonest vascular cause stroke dementia. Hypertension most established risk factor for SVD, but pathophysiological mechanisms following hypertension that SVD remain poorly understood. We aim to examine effects changes in blood pressure on microvasculature young- middle-aged adults with detect earliest microvascular associated SVD.The Hyperintense study an ongoing observational cohort aiming include 50...
Li-Fraumeni syndrome (LFS) is an autosomal dominant cancer predisposition syndrome. Germline pathogenic/likely pathogenic variants (P/LPVs) in the TP53 gene are only known genetic cause of this entity. Due to severe phenotype and controversy over increasing surveillance risk-reducing measures, testing has traditionally been offered when strict criteria were met. However, with application next generation sequencing (NGS) multigene (MGT), such as hereditary breast panels, being increasingly...
Acute interstitial nephritis (AIN) corresponds to a decline in kidney function due an injury induced by drugs (in the majority of cases), infections, and autoimmune disorders. It is characterized presence inflammatory infiltrate kidney. Here, we describe case man with previous medical history relevant ulcerative colitis (UC) who was admitted acute (AKI) setting AIN secondary mesalazine.