A5014513275- Heart Rate Variability and Autonomic Control
- Blood Pressure and Hypertension Studies
- Cardiovascular Health and Disease Prevention
- Stress Responses and Cortisol
- Cardiovascular Function and Risk Factors
- Intensive Care Unit Cognitive Disorders
- Cardiac, Anesthesia and Surgical Outcomes
- Cardiovascular and exercise physiology
- Cardiovascular Syncope and Autonomic Disorders
- Non-Invasive Vital Sign Monitoring
- Neuroscience of respiration and sleep
- Hip and Femur Fractures
- Cardiac electrophysiology and arrhythmias
- Anesthesia and Sedative Agents
- Circadian rhythm and melatonin
- Nitric Oxide and Endothelin Effects
- Hemodynamic Monitoring and Therapy
- Nutrition and Health in Aging
- Cardiac Imaging and Diagnostics
- Health Systems, Economic Evaluations, Quality of Life
- Geriatric Care and Nursing Homes
- Schizophrenia research and treatment
- Anesthesia and Neurotoxicity Research
- Eicosanoids and Hypertension Pharmacology
- Frailty in Older Adults
Santa Maria Nuova Hospital
2022-2024
University of Parma
2022
Azienda Sanitaria Unità Locale di Reggio Emilia
2009-2020
Italian Society of Physiotherapy
2017-2018
Istituti di Ricovero e Cura a Carattere Scientifico
2000-2016
University of Milan
1987-2013
Ospedale Santa Maria
2010-2013
University of Milano-Bicocca
1999-2010
University of Pavia
2000-2007
Azienda Ospedaliera San Gerardo
1992-2007
We studied the neural determinants of second (i.e., high frequency, HF)- and third-order low LF) spontaneous oscillations heart period (R-R interval) arterial pressure (AP) in conscious dogs, with hypothesis that they might furnish quantitative markers autonomic controlling activities. Spectral analysis simultaneous R-R AP variabilities quantified these were also evaluated units normalized by total power to focus on balance two major components. At rest we observed a prevalent HF component...
To date, delirium prevalence in adult acute hospital populations has been estimated generally from pooled findings of single-center studies and/or among specific patient populations. Furthermore, the number participants these not exceeded a few hundred. overcome limitations, we have determined, multicenter study, over single day large population patients admitted to and rehabilitation wards Italy. This is point study (called "Delirium Day") including 1867 older (aged 65 years or more) across...
In schizophrenia and major depressive disorder, anhedonia (a loss of capacity to feel pleasure) had differently been considered as a premorbid personological trait or main symptom their clinical picture. The aims this study were examine the pathological features in schizophrenic depressed patients, investigate its relations with general psychopathology (negative, positive, dimensions).A total 145 patients (80 schizophrenics 65 subjects) assessed using Physical Anhedonia Scale Social (PAS...
Objectives Viscous and inertial components contribute to arterial distensibility compliance in vitro. The purpose of our study was determine whether this phenomenon is relevance vivo, namely, altered by an increase heart rate Design Arterial diameter assessed echo-Doppler device a common carotid femoral artery, large elastic muscle artery. studies were performed 12-week-old pentobarbitone-anaesthetized Wistar-Kyoto rats subjected atrial pacing via transjugular unipolar catheter at five...
We studied the control of arterial pressure by carotid sinus baroreceptors in 35 hypertensive humans, using a variable neck chamber to alter transmural graded fashion. The results were compared with those obtained from 11 normotensives. As normotensives, reduction caused linearly related pressor response and vice versa. However, whereas normotensives was greater than depressor, reverse case hypertensives. Furthermore, decreased depressor increased progressively an increase severity...
1. The variable-pressure neck-chamber method was analysed in ten healthy volunteer subjects to determine its suitability for the study of carotid baroreceptor reflex man. 2. Positive and negative pressures applied neck (range ± 60 mmHg) were always transmitted linearly a tissue catheter outside sinus, but only 86% positive pressure, 64% pressure. Tissue confirmed by simultaneous measurement internal jugular vein adjacent sinus. 3. pressure changes within above range did not alter Po2 venous...
The carotid sinus baroreceptor reflex was studied in 11 normotensive subjects, using a variable pressure neck chamber and correcting for imperfect transmission to the sinus. Decreased stimulation caused sustaineded rise arterial pressure, increased sustain fall. responses were linear relation stimulus, and, after reaching steady state, greater reduced than stimulation. Thus of man is an effective antihypotensive antihypertensive feedback system, though former function may have more...
Sinoaortic denervation (SAD) is accompanied by an increase in blood pressure (BP) and a reduction pulse-interval (PI) variance. Little known, however, about the effect of SAD on complex BP PI variability pattern, which identified spectral analysis. In nine unanesthetized cats intra-arterial was monitored before 7-10 days after SAD, powers (estimated fast Fourier transform) were calculated for low frequency (LF, 0.025-0.07 Hz), midfrequency (MF, 0.07-0.14 high (HF, 0.14-0.60 Hz) band. The...
Delirium is a common geriatric syndrome. Few studies have been conducted in nursing home (NH) residents. The aim of this project was to perform point prevalence study delirium Italian NHs.Data collected 71 NHs are presented. Inclusion criteria were age ≥65 years and native speaker. Exclusion coma, aphasia, end-of-life status. Sociodemographic medical data recorded. assessed using the Assessment Test for Cognitive Impairment (4-AT). Patients with 4-AT score ≥4 considered delirium. Motor...
The arterial baroreceptor control of the sinus node operating in unanesthetized conditions was evaluated 10 cats which blood pressure recorded intra-arterially and scanned by a computer to identify "spontaneous" sequences three or more consecutive beats systolic (SBP) progressively rose pulse interval (PI) lengthened (type 1 sequences) SBP fell PI shortened 2 sequences). Many type three-beat were found; four-, five-, six-beat either less common, longer than six almost never identified....
1. Intra-arterial blood pressure and heart rate were recorded for 24 h in ambulant hospitalized patients of variable age who had normal or essential hypertension. Mean values, standard deviations variation coefficient obtained as the averages values separately analysed 48 consecutive half-hour periods. 2. In older subjects deviation mean arterial greater than younger with similar whereas smaller. 3. hypertensive was normotensive ages, but this not case coefficient, which slightly smaller...
Data in animals indicate that large amounts of digitalis potentiate arterial baroreflexes and this factor may be important for the cardiovascular effects drug. To determine if baroreflex potentiation also exists after administration therapeutic doses man, we studied how stimulation deactivation baroreceptors by phenylephrine nitroglycerin injection affect heart rate carotid neck suction pressure affects blood rate. The study was performed 29 normotensive or hypertensive subjects before...
The adaptive changes that develop in the pressure-overloaded left ventricular (LV) myocardium include cardiomyocyte hypertrophy and interstitial fibrosis. Although former is known to depend a sizeable extent on sympathetic (over)activity, little information exists whether same applies latter, ie, excess catecholamine exposure contributes imbalance between collagen deposition by fibroblasts degradation matrix metalloproteases (MMPs), eventually leading LV accumulation. Sprague-Dawley rats...
Slow, controlled breathing has been shown by cross-spectral techniques to potentiate arterial baroreflex control of heart rate. However, crucial aspects the effects slow on remain unsettled, namely whether major function (i.e. blood pressure) is also potentiated and differentially modulated according age individual.To examine bradycardic depressor responses selective carotid baroreceptor stimulation neck chamber technique (-15 -30 mmHg suction) R-R interval/systolic pressure relationship...