Antonio De Simone

ORCID: 0000-0003-2003-6097
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About
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Research Areas
  • Advanced Radiotherapy Techniques
  • Prostate Cancer Diagnosis and Treatment
  • Advanced MRI Techniques and Applications
  • Prostate Cancer Treatment and Research
  • Radiation Therapy and Dosimetry
  • Ancient Mediterranean Archaeology and History
  • Medical Imaging Techniques and Applications
  • MRI in cancer diagnosis
  • Modular Robots and Swarm Intelligence
  • Cardiac Arrhythmias and Treatments
  • Atrial Fibrillation Management and Outcomes
  • Building Energy and Comfort Optimization
  • Educational and Social Studies
  • Meningioma and schwannoma management
  • Noise Effects and Management
  • Micro and Nano Robotics
  • Classical Antiquity Studies
  • Radiation Dose and Imaging
  • Urban Heat Island Mitigation
  • Historical and Religious Studies of Rome
  • Spinal Fractures and Fixation Techniques
  • Advanced Materials and Mechanics
  • Botulinum Toxin and Related Neurological Disorders
  • Ship Hydrodynamics and Maneuverability
  • Vehicle Noise and Vibration Control

Ospedale Sacro Cuore Don Calabria
2020-2025

Università degli Studi Suor Orsola Benincasa
2018-2025

Casa di Cura San Michele
2023-2024

Scuola Superiore Sant'Anna
2019-2024

Scuola Internazionale Superiore di Studi Avanzati
2016-2024

Unilever (United Kingdom)
2022-2023

University of Bedfordshire
2023

Istituti di Ricovero e Cura a Carattere Scientifico
2022

Istituto Nazionale di Fisica Nucleare, Sezione di Trieste
2021

University of Urbino
2020

10.1007/bf00376811 article EN Archive for Rational Mechanics and Analysis 1993-06-01

Unity Elekta is a unique magnetic resonance (MR)-linac that conjugates 1.5 Tesla MR unit with 7 MV flattening filter free accelerator.A prospective observational study for the clinical use of currently ongoing in our department. Herein, we present preliminary report on feasibility, quality life, and patient-reported outcomes measures (PROMs) localized prostate cancer (PC) treated stereotactic body radiotherapy (SBRT).The SBRT protocol consisted 35 Gy schedule delivered 5 fractions within 2...

10.1186/s13014-020-01510-w article EN cc-by Radiation Oncology 2020-03-23

Adaptive stereotactic body radiation therapy (SBRT) for prostate cancer (PC) by the 1.5 T MR-linac currently requires online planning an expert user. A fully automated and user-independent solution to adaptive (mCycle) of PC-SBRT was compared with user's plans MR-linac.Fifty adapted on daily magnetic resonance imaging scans 10 patients PC treated 35 Gy (prescription dose [Dp]) in 5 fractions were reoptimized offline from scratch, both planner (manual) mCycle. Manual consisted multicriterial...

10.1016/j.adro.2021.100865 article EN cc-by Advances in Radiation Oncology 2022-02-12

Aim To evaluate differences between MR-guided daily-adaptive RT (MRgRT) and image-guided (IGRT) with or without fiducial markers in prostate cancer (PCa) stereotactic body radiotherapy (SBRT) terms of dose distribution on critical structures.Material methods Two hundred treatment sessions 40 patients affected by low intermediate PCa were evaluated. The prescribed was 35 Gy 5 fractions delivered alternate days. MRgRT (10) daily recontoured, re-planned, treated IMRT technique. IGRT (20)...

10.1080/0284186x.2020.1821090 article EN Acta Oncologica 2020-09-18

Abstract Background The assessment of organ motion is a crucial feature for prostate stereotactic body radiotherapy (SBRT). Rectal spacer may represent helpful device in order to outdistance rectal wall from clinical target, but its impact on still matter debate. MRI-Linac new frontier radiation oncology as it allows superior visualization the real-time anatomy patient and current highest level adaptive radiotherapy. Methods We present data regarding total 100 fractions 20 patients who...

10.1186/s13014-020-01622-3 article EN cc-by Radiation Oncology 2020-07-22

The main aim of the current analysis was to explore hypothetical advantages using rectal spacer during 1.5T MR-guided and daily adapted prostate cancer stereotactic body radiotherapy (SBRT) compared a no-rectal hydrogel cohort patients.The SBRT-protocol consisted 35 Gy schedule delivered in 5 fractions. Herein, we present dosimetric between no-spacer patients. Furthermore, treatment tolerability feasibility were preliminarily assessed according clinicians-reported outcomes at end...

10.1259/bjr.20200848 article EN British Journal of Radiology 2020-10-23
Enrico Virgilio Caterina Trevisan Angela Marie Abbatecola Alba Malara A. Palmiéri and 95 more Giorgio Fedele Paola Stefanelli Pasqualina Leone Ilaria Schiavoni Stefania Maggi Stefano Volpato Raffaele Antonelli Incalzi Graziano Onder Angela Marie Abbatecola Domenico Andrieri Raffaele Antonelli Incalzi Francesca Arenare Viviana Bagalà Tatjana Baldovin Riccardo Bernardi Alessandra Bianchi Paola Bianchi Raffaella Bisceglia Ivan Bissoli Fabio Bontempi Gilda Borselli Luigi Carlo Bottaro Elisa Bottoni Silvia Brandi Claudio Bravin Maria Adele Buizza Carmine Cafariello Alessia Maria Calabrese Valeria Calsolaro M. Canepa Carla Capasso Mariagrazia Capuano Sebastiano Capurso Gabriele Carbone M. Carducci Silvia Carino N. Cattaneo Francesco Ceravolo Maria Angelica Dorotea Chiesara Danila Clerici Pierpaolo Clerici Alessandra Coin Vieri Collacchioni Mauro Colombo Michela Compiano Giuseppina Costanza Giovanna Crupi Roberta Cucunato Manuela Marina D'Abramo E. D’Agostino Ferdinando D’Amico Antonio De Simone Stefania Vecchio Maria Deleo Annalaura Dell’Armi Tommasina Di Brango Anna Di Lonardo Maria Raffaella Di Nanno Babette Dijk Luisa Elmo Giorgio Fedele Marisa Ferraro Christian Ferro Claudia Fiorucci Francesca Fortunato Pasquale Froncillo Doménico Galasso Nicola Galdiero Caterina Galdiero Stefania Gallo Pier Paolo Gasbarri Maria Grazia Gennai Giuliana Ghiselli Ricci Elisa Giribaldi Carmen Godeanu Samuele Gommaraschi Roberta Granata Giada Ida Greco Angela Greco Antônio Grillo Gianbattista Guerrini Mauro Guglielmo Labjona Haxhiaj Claudio Giuseppe Iacovella M. INDINO Valerio Alex Ippolito David Kanah Liudmila Kountsevich Jovan Leci Federica Limongi Agata Lipari Vincenzo Longo Stefania Maggi Alba Malara L Maltese

OBJECTIVE Type 2 diabetes may affect the humoral immune response after vaccination, but data concerning coronavirus disease 19 (COVID-19) vaccines are scarce. We evaluated impact of on antibody to severe acute respiratory syndrome (SARS-CoV-2) vaccination in older residents long-term care facilities (LTCFs) and tested for differences according antidiabetic treatment. RESEARCH DESIGN AND METHODS For this analysis, 555 LTCFs participating GeroCovid Vax study were included. SARS-CoV-2 trimeric...

10.2337/dc22-1255 article EN Diabetes Care 2022-10-06

A key challenge in the art and archaeological field is instrumental analysis of objects materials while preserving their integrity. In this study, world-renowned artwork Alexander Mosaic (The Issus Battle, collection National Archaeological Museum Naples, IT), most iconic representation face Macedonian king Great coming from a Pompeii domus, was thoroughly analyzed with mobile non-invasive methods, within great project restoration started 2020. Representative areas Mosaic, overall consisting...

10.1371/journal.pone.0315188 article EN cc-by PLoS ONE 2025-01-15

Prostate re-irradiation is an attractive treatment option in the case of local relapse after previous radiotherapy, either definitive or post-operative setting. In this scenario, introduction MR-linacs may represent a helpful tool to improve accuracy and precision treatment.This study reports preliminary data cohort 22 patients treated with 1.5T MR-Linacs for prostate bed re-irradiation. Toxicity was prospectively assessed collected according CTCAE v5.0. Survival endpoints were measured...

10.3389/fonc.2022.858740 article EN cc-by Frontiers in Oncology 2022-04-13

The quest for an intuitive and physiologically appropriate human-machine interface the control of dexterous prostheses is far from being completed. To a hand prosthesis, possible approach could consist in using information related to displacement forearm muscles amputee during contraction. We recently proposed that muscle be monitored by implanting passive magnetic markers (MMs- i.e., permanent magnets) them. dubbed this myokinetic interface. However, besides system feasibility, how much its...

10.1109/tbme.2019.2935229 article EN IEEE Transactions on Biomedical Engineering 2019-08-14

Seed dispersal strategies exemplify the role of morphology in defining falling paths. Here, macroscopic geometry effects are systematically studied by considering trajectories annular disks. Via linear stability analysis, we identify boundary for vertical fall, with a non-monotonic behavior critical velocity hole size, before increasing large holes. Nonlinear simulations confirm analyses and suggest seed release at different heights, emergence paths possibly beneficial controlled positioning...

10.1103/physrevfluids.9.043907 article EN Physical Review Fluids 2024-04-17
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