A5089994226- SARS-CoV-2 and COVID-19 Research
- COVID-19 Clinical Research Studies
- Influenza Virus Research Studies
- SARS-CoV-2 detection and testing
- Bacterial Identification and Susceptibility Testing
- Respiratory viral infections research
- COVID-19 epidemiological studies
- Sepsis Diagnosis and Treatment
- Nosocomial Infections in ICU
- Urinary Tract Infections Management
- Viral gastroenteritis research and epidemiology
- Electronic Health Records Systems
- Emergency and Acute Care Studies
- Orthopaedic implants and arthroplasty
- Salmonella and Campylobacter epidemiology
- Clostridium difficile and Clostridium perfringens research
- Orthopedic Infections and Treatments
- Pneumonia and Respiratory Infections
- COVID-19 and healthcare impacts
- Data-Driven Disease Surveillance
- Long-Term Effects of COVID-19
- Microscopic Colitis
- COVID-19 diagnosis using AI
- Infective Endocarditis Diagnosis and Management
- Animal Disease Management and Epidemiology
Statens Serum Institut
2014-2024
Ontario Institute for Cancer Research
2017
University Hospitals Birmingham NHS Foundation Trust
2017
Laboratoire National de Santé
2017
Biology of Infection
2017
Engineering Associates (United States)
2017
European Centre for Disease Prevention and Control
2010-2012
Leiden University Medical Center
2006
Population-level knowledge on individuals at high risk of severe and fatal coronavirus disease 2019 (COVID-19) is urgently needed to inform targeted protection strategies in the general population.We examined characteristics predictors hospitalization death a nationwide cohort all Danish tested for acute respiratory syndrome 2 (SARS-CoV-2) from 27 February 2020 until 19 May 2020.We identified 11 122 SARS-CoV-2 polymerase chain reaction-positive cases whom 80% were community-managed 20%...
The more infectious SARS-CoV-2 lineage B.1.1.7 rapidly spread in Europe after December, 2020, and a concern that could cause severe disease has been raised. Taking advantage of Denmark's high RT-PCR testing whole genome sequencing capacities, we used national health register data to assess the risk COVID-19 hospitalisation individuals infected with compared those other lineages.We did an observational cohort study all SARS-CoV-2-positive cases confirmed by Denmark, sampled between Jan 1...
A highly virulent sub-lineage of the Streptococcus pyogenes M1 clone has been rapidly expanding throughout Denmark since late 2022 and now accounts for 30% new invasive group streptococcal infections. We aimed to investigate whether a shift in variant composition can account high incidence rates observed over winter 2022/23, or if these are better explained by impact COVID-19-related restrictions on population immunity carriage .
Background: The more infectious SARS-CoV-2 virus lineage B.1.1.7, rapidly spread in Europe after December 2020, and a concern of B.1.1.7 causing severe disease has been raised. Denmark one Europe´s highest capacities per capita reverse transcription polymerase chain reaction (RT PCR) test whole genome sequencing (WGS). We used national health register-data to explore whether increases the risk COVID-19 hospitalisation. Methods Findings: In an observational cohort study we included all RT PCR...
Healthcare-associated infections (HAI) are among the most common adverse events of medical care. Surveillance HAI is a key component successful infection prevention programmes. Conventional surveillance - manual chart review resource intensive and limited by concerns regarding interrater reliability. This has led to development use automated (AS). Many AS systems product in-house efforts heterogeneous in their design methods. With this roadmap, PRAISE network aims provide guidance on how...
As most automated surveillance (AS) methods to detect healthcare-associated infections (HAIs) have been developed and implemented in research settings, information about the feasibility of large-scale implementation is scarce.To describe key aspects design AS systems European institutions hospitals.An online survey was distributed via e-mail February/March 2019 among (i) PRAISE (Providing a Roadmap for Automated Infection Surveillance Europe) network members; (ii) corresponding authors...
Background: Using nation-wide Danish register data, we investigated whether BA.2.86, including JN.1, differed from other circulating variants in terms of ability to escape vaccine protection, risk severe disease, and self-reported symptoms.Methods: We included all residents over 65 years age with a positive SARS-CoV-2 PCR test available genomic variant data between October 1, 2023 December 10, 2023. Data clinical testing, sentinel self-sampling-based surveillance were linked national...
Background: Estimates of the severity emerging Omicron variant (lineage B.1.1.529) are critical to assess public health impact associated with its rapid global dissemination. We estimated risk SARS-CoV-2-related hospitalizations after infection compared Delta overall and stratified by vaccination status in Denmark, a country high mRNA coverage an extensive free-of-charge PCR test capacity.Methods: Observational cohort study all RT-PCR SARS-CoV-2 positive individuals Denmark between 21...
An abstract is not available for this content so a preview has been provided. As you have access to content, full PDF via the 'Save PDF' action button.
Binary file ES_Abstracts_Final_ECDC.txt matches
Healthcare-associated infections (HAI) are a major public health concern. Monitoring of HAI rates, with feedback, is core component infection prevention and control programmes. Digitalization healthcare data has created novel opportunities for automating the surveillance process to varying degrees. However, methods not standardized vary widely between different facilities. Most current automated (AS) systems have been confined local settings, practical guidance on how implement large-scale...
Background: In Denmark, large-scale waterborne outbreaks are rare. This report describes the investigation of an outbreak that occurred in town Køge May 2010. Methods: The epidemiological consisted hypothesis generating telephone interviews, followed by a cohort study among approximately 20,000 residents using online questionnaire. Odds ratios were calculated for exposures including number glasses tap water consumed. Geographical spreading was assessed geographical information system....
The objective of this study was to describe the clinical course severe and complicated pandemic (H1N1)v infection treated with oral oseltamivir inhaled zanamivir in a series intensive care patients.We investigated case patients respiratory failure positive real-time reverse transcriptase polymerase chain reaction (rRT-PCR). Treatment consisted tablets 75 mg × 4 daily nasogastric tube plus intravenous (i.v.) solution 25 as inhalation. Ventilator inspiratory plateau airway pressure ventilator...
BACKGROUND In 2015, Denmark launched an automated surveillance system for hospital-acquired infections, the Hospital-Acquired Infections Database (HAIBA). OBJECTIVE To describe algorithm used in HAIBA, to determine its concordance with point prevalence surveys (PPSs), and present trends bacteremia SETTING Private public hospitals METHODS A case was defined as at least 1 positive blood culture pathogen (bacterium or fungus) taken between 48 hours after admission discharge, using Danish...
Abstract Objective To provide population-level knowledge on individuals at high risk of severe and fatal coronavirus disease 2019 (COVID-19) in order to inform targeted protection strategies the general population appropriate triage hospital contacts. Design, Setting, Participants Nationwide population-based cohort all 228.677 consecutive Danish tested (positive or negative) for acute respiratory syndrome 2 (SARS-CoV-2) RNA from identification first COVID-19 case February 27 th , 2020 until...
Abstract The immune response against human adenovirus (HAdV) has gained interest because of the application HAdV‐based vectors in gene therapy and high incidence infections pediatric recipients allogeneic stem cell grafts. Because antiviral medication is frequently ineffective, option adoptive transfer HAdV‐specific donor‐derived T cells these immunocompromised patients investigated. To generate good manufacturing practice‐compatible reagents, a panel 63 long, overlapping, peptides hexon...