A5083862626- Antimicrobial Resistance in Staphylococcus
- Migraine and Headache Studies
- Mycobacterium research and diagnosis
- Microbial infections and disease research
- Pneumonia and Respiratory Infections
- Monoclonal and Polyclonal Antibodies Research
- Trigeminal Neuralgia and Treatments
- Cystic Fibrosis Research Advances
- Bacterial biofilms and quorum sensing
- Bacteriophages and microbial interactions
- Pain Mechanisms and Treatments
- Antibiotic Resistance in Bacteria
- Advanced biosensing and bioanalysis techniques
- Cardiovascular Syncope and Autonomic Disorders
- Bacterial Identification and Susceptibility Testing
- Bacterial Infections and Vaccines
- Ophthalmology and Eye Disorders
- Vestibular and auditory disorders
- Contact Dermatitis and Allergies
- DNA and Nucleic Acid Chemistry
- Clostridium difficile and Clostridium perfringens research
- Olfactory and Sensory Function Studies
- Enterobacteriaceae and Cronobacter Research
- Antibiotics Pharmacokinetics and Efficacy
- Cell Adhesion Molecules Research
Ronald Reagan UCLA Medical Center
2024
Roche (Denmark)
2019-2022
American University
2014
University of Maryland, Baltimore
2014
University of Copenhagen
1958-2012
Statens Serum Institut
1969-2011
Gentofte Hospital
1984-2009
Rigshospitalet
1970-2009
Vejle Sygehus
1998
Hvidovre Hospital
1979-1995
The present study was undertaken to investigate the frequency of nasal carrier rate Staphylococcus aureus. investigation performed on 104 healthy persons. total number swabs 1498 and this resulted in isolation 522 S. aureus strains. All strains have been identified, tested for antibiotic susceptibility, phage-typed. carrier-index (number positive swabs/number each individual person) compared with different sampling culturing methods, phage type, age, resistance antibiotics. There statistical...
Høiby, N., Friis, B., Jensen, K., Koch, C, Møller, N.E., Støvring, S. and Szaff, M. (Statens Seruminstitut, Departments of Clinical Microbiology at Rigshospitalet Hvidovre Hospital, Paediatric Department TG, Rigshospitalet, Copenhagen, Denmark). Antimicrobial chemotherapy in cystic fibrosis patients. Acta Paediatr Scand 1982; suppl 301: 75‐100. — Every effort should be undertaken to combat recurrent chronic bacterial respiratory tract infections patients with because are the main...
Systematic prospective records of aura symptoms were obtained from 50 patients, who filled in report forms during the phase two attacks. The pattern various was remarkably constant Visual recorded by 94% somato-sensory 40%, motor disturbances 18% and speech difficulties 20%. unilateral 55%, 80% 100%. Surprisingly, headache absent 20% When occurred same attack, most often contralateral to symptoms. Our observations are accordance with hypothesis that pathophysiological process responsible for...
Extra-intestinal pathogenic Escherichia coli (ExPEC) causing urinary tract infections (UTIs) most often belong to phylogenetic group B2 and stem from the patient's own faecal flora. It has been hypothesized that external reservoir for these uropathogenic E. in human intestine may be meat food-production animals. To investigate such a connection, this study analysed an phylogroup strain collection (n = 161) of geographical temporally matched isolates, published previously, UTI patients 52),...
During dynamic exercise, mean blood velocity ( V ) in the middle cerebral artery (MCA) demonstrates a graded increase to work rate and reflects regional flow. At high rate, however, vasoactive levels of plasma catecholamines could mediate vasoconstriction MCA thereby elevate at given volume To evaluate transcranial Doppler‐determined catecholamine levels, seven elite cyclists performed maximal performance test on bicycle ergometer. Results were compared with those elicited during five...
During the past year five patients from countries in Middle East admitted to a burns unit were found harbour strain of Staphylococcus aureus with unusual multi-resistance antibiotics. The admission first patient was followed by an outbreak infection this involving ten unit. In addition staff members be nasal carriers strain. As result incident, following four isolated on and spread their strans thus prevented. It is recommended that units, or similar departments very susceptible infection,...
Common Antigen (CA) of Pseudomonas aeruginosa has been shown to be a protein composed polypeptide subunits molecular weight (MW) about 62 000. The MW this was estimated 665 000 by gel filtration on Sepharose CL‐6B, 800 electrophoresis polyacrylamide gradient gels and 900 ultracentrifugation, sucrose gradient. By analytical ultracentrifugation with Schlieren optics sedimentation coefficient (S 20 , w) 22.65 calculated. isoelectrical point determined pH 4.4. antigen decomposed exposure...
ABSTRACT Antibiotic treatment of Staphylococcus aureus infections is often problematic due to the slow response and recurrences. The intracellular persistence staphylococci offers a plausible explanation for difficulties because impaired efficacies antibiotics. intra- extracellular time- concentration-kill relationships were examined in vitro with THP-1 cells vivo by use mouse peritonitis model. model was further used estimate most predictive pharmacokinetic/pharmacodynamic (PK/PD) indices...
The introduction of non-bridging phosphorothioate (PS) linkages in oligonucleotides has been instrumental for the development RNA therapeutics and antisense oligonucleotides. This modification offers significantly increased metabolic stability as well improved pharmacokinetic properties. However, due to chiral nature phosphorothioate, every PS group doubles amount possible stereoisomers. Thus are generally obtained an inseparable mixture a multitude diastereoisomeric compounds. Herein, we...
In serum from an apparently healthy male, three M‐components were found by Immunoelectrophoresis, γA (α 2 κ ), γG (γ and γM (μ Λ ) 6 ). No Bence Jones proteins present in or urine.
The aim of this study was to isolate novel antibiofilm compounds produced by environmental bacteria. Cell‐free extracts were prepared from lawns bacteria cultured on agar. A total 126 isolated soil, cave and river habitats employed. Extracts tested for their ability inhibit Staphylococcus aureus biofilm in a 96‐well microtitre plate assay. 55/126 (44%) significantly inhibited Staph. biofilm. Seven selected further analysis. activities all seven exhibited unique patterns molecular mass,...
An improved radio-immunoassay using an antiserum directed towards the N-terminal part of endogenous opioid peptide beta-endorphin 1-31 (beta-EP) was validated and applied to a study beta-EP in plasma during ischaemic pain. Experimental pain induced seven healthy volunteers by submaximal effort tourniquet test did not change or adrenocorticotrophin. Plasma determined 21 patients with acute myocardial infarction (AMI) unstable angina pectoris. 4.9 fmol/ml 95% confidence limits, 3.2-7.8 AMI at...
Fifty-three patients with cystic fibrosis were treated large doses of tobramycin sulphate, 10 mg/kg/24 h. Patients received an average 3.2 courses, each lasting to 14 days. The examined audiometric and vestibular tests, in one patient, a 10-year-old girl, we found transient high tone loss at 8000 Hz bilaterally that might be attributed the treatment. All had normal kidney function. High dose treatment children function gives minimal clinical risks adverse ototoxic effects, even after repeated courses
In the present study we investigate optimal methodology for determination of nasal carriage rate Staphylococcus aureus . Tests were performed on 91 healthy laboratory staff. The reproducibility different sampling, transportation, storage and culture methods was examined. We compared sterile dry cotton wool swabs with impregnated charcoal 5% blood agar plates mannitol salt after incubation periods. Finally, investigated detection S. following direct plating to in Stuart's transport medium 7...