A5004434922- Antibiotics Pharmacokinetics and Efficacy
- Antibiotic Resistance in Bacteria
- Antimicrobial Resistance in Staphylococcus
- Lipid Membrane Structure and Behavior
- Drug Transport and Resistance Mechanisms
- Pneumonia and Respiratory Infections
- Bacterial biofilms and quorum sensing
- Bacterial Identification and Susceptibility Testing
- Lysosomal Storage Disorders Research
- Cellular transport and secretion
- Biomedical Research and Pathophysiology
- Metabolism and Genetic Disorders
- Amino Acid Enzymes and Metabolism
- Antimicrobial Peptides and Activities
- Antibiotic Use and Resistance
- Erythrocyte Function and Pathophysiology
- Cancer therapeutics and mechanisms
- Protein Interaction Studies and Fluorescence Analysis
- Sphingolipid Metabolism and Signaling
- Pharmaceutical Practices and Patient Outcomes
- Neonatal Health and Biochemistry
- Monoclonal and Polyclonal Antibodies Research
- Pharmaceutical studies and practices
- Pharmacological Effects and Toxicity Studies
- Biochemical and Structural Characterization
UCLouvain
2015-2024
Service Public Fédéral Technologie de l'Information et de la Communication
2018
FOD Volksgezondheid, Veiligheid van de Voedselketen en Leefmilieu
2018
Université des Sciences, des Techniques et des Technologies de Bamako
2017
Merck & Co., Inc., Rahway, NJ, USA (United States)
2017
Laboratoire de Chimie Physique
2015
Institute of Molecular and Cell Biology
2015
UCB Pharma (Belgium)
2014
University College Lahore
2014
University of Mons
1986-2011
OBJECTIVES: To evaluate the effect of pharmaceutical care provided in addition to acute Geriatric Evaluation and Management (GEM) on appropriateness prescribing. DESIGN: Randomized, controlled trial, with patient as unit randomization. SETTING: Acute GEM unit. PARTICIPANTS: Two hundred three patients aged 70 older. INTERVENTION: Pharmaceutical from admission discharge by a specialist clinical pharmacist who had direct contacts team patients. MEASUREMENTS: Appropriateness prescribing...
The pharmacodynamic properties governing the activities of antibiotics against intracellular Staphylococcus aureus are still largely undetermined. Sixteen seven different pharmacological classes (azithromycin and telithromycin [macrolides]; gentamicin [an aminoglycoside]; linezolid oxazolidinone]; penicillin V, nafcillin, ampicillin, oxacillin [beta-lactams]; teicoplanin, vancomycin, oritavancin [glycopeptides]; rifampin ansamycin]; ciprofloxacin, levofloxacin, garenoxacin, moxifloxacin...
ABSTRACT The stability of antipseudomonal β-lactams in concentrated solutions was examined view their potential administration by continuous infusion with external pumps (for intensive care patients) or portable carried under clothing cystic fibrosis patients). Aztreonam (100 g/liter), piperacillin (128 g/liter, tazobactam), and azlocillin g/liter) remained 90% stable for up to more than 24 h at 37°C (mezlocillin [128 g/liter] 25°C but not 37°C). Ceftazidime (120 cefpirome (32 cefepime (50...
In contrast to currently marketed fluoroquinolones, which are zwitterionic, delafloxacin is an investigational fluoroquinolone with anionic character that highly active against Gram-positive bacteria. We have examined the effect of acidic pH on its accumulation in Staphylococcus aureus and human THP-1 cells, parallel activity extracellular intracellular S. aureus. Moxifloxacin was used as a comparator. Delafloxacin showed MICs 3 5 log(2) dilutions lower than those moxifloxacin for collection...
Cultured rat embryo fibroblasts were first allowed to store for 24 h fluorescein-labeled goat immunoglobulins directed against rabbit (F anti-R IgG), and subsequently exposed [(3)H]acetylated known bind the cell membrane either specifically (anti-plasma IgG: A anti-PM IgG) or unspecifically (contol AC IgG). As a result of immunological interaction between two antibodies (no effect was found if cells had been preloaded with control FC substantial portion stored F IgG unloaded from its...