A5101755431- Bacterial Identification and Susceptibility Testing
- Gut microbiota and health
- Streptococcal Infections and Treatments
- Probiotics and Fermented Foods
- Mycobacterium research and diagnosis
- Mitochondrial Function and Pathology
- Microbial infections and disease research
- Genetic Neurodegenerative Diseases
- Milk Quality and Mastitis in Dairy Cows
- Bartonella species infections research
- Fungal and yeast genetics research
- Genomics and Phylogenetic Studies
- Antimicrobial Resistance in Staphylococcus
- Neonatal and Maternal Infections
- Viral Infections and Vectors
Statens Serum Institut
2023-2024
Copenhagen University Hospital
2022
Kennedy Center
2022
Rigshospitalet
2022
A highly virulent sub-lineage of the Streptococcus pyogenes M1 clone has been rapidly expanding throughout Denmark since late 2022 and now accounts for 30% new invasive group streptococcal infections. We aimed to investigate whether a shift in variant composition can account high incidence rates observed over winter 2022/23, or if these are better explained by impact COVID-19-related restrictions on population immunity carriage .
Myotonic dystrophy type 1 (DM1) is a multisystemic neuromuscular disorder caused by the expansion of CTG repeat in 3'-UTR DMPK, which transcribed to toxic gain-of-function RNA that affects splicing range genes. The expanded unstable both germline and somatic cells. variable age at disease onset severity symptoms have been linked inherited length, non-CTG interruptions, methylation levels flanking repeat. In general, genetic biomarkers are investigated separately with specific methods, making...
Metagenomic sequencing is a promising method that has the potential to revolutionize world of pathogen detection and antimicrobial resistance (AMR) surveillance in food-producing environments. However, analysis huge amount data obtained requires performant bioinformatics tools databases, with intuitive straightforward interpretation. In this study, based on long-read metagenomics chicken fecal samples spike-in mock community, we proposed confidence levels for taxonomic identification AMR...
Abstract Linezolid resistance in Enterococcus spp. is increasingly considered critically important and a public health threat which mandates the need to understand their genomic contents dissemination patterns. Here, we used whole-genome sequencing characterize resistome, virulome mobile genetic elements of nine linezolid-resistant (LZD R ) enterococci (seven optrA - E. faecalis, one poxtA faecium casseliflavus previously obtained from nares healthy dogs, pigs, pig farmers tracheal samples...
Abstract Background Linezolid resistance in Enterococcus faecalis (a normal gut bacterium) is increasingly considered a critical public health concern, hence the need to understand their genomic contents and dissemination patterns. Methods Illumina-based sequencing was used characterize seven linezolid-resistant (LZDR) E. strains obtained from nares of healthy humans animals Spain. Also, relatedness with publicly available genomes similar lineages AMR determinants accessed by core-genome SNP...
A panaritium developed in a woman Demark after her cat scratched her. Analysis of tissue by 16S rRNA gene sequencing revealed Mycoplasma phocimorsus, known to cause seal finger. The source the bacterium likely transmitted is unknown, but awareness potential zoonotic transmission from cats should be raised.