- Endodontics and Root Canal Treatments
- Dental Radiography and Imaging
- Dental materials and restorations
- Dental Erosion and Treatment
- Oral microbiology and periodontitis research
- Dental Health and Care Utilization
- Occupational health in dentistry
- Dental Research and COVID-19
- Forensic Toxicology and Drug Analysis
- Dental Trauma and Treatments
- Dental Anxiety and Anesthesia Techniques
- Fluoride Effects and Removal
- Dental Implant Techniques and Outcomes
- Plasma Applications and Diagnostics
- Drilling and Well Engineering
- Metabolomics and Mass Spectrometry Studies
- Advanced Chemical Sensor Technologies
- Bone and Dental Protein Studies
- Psychedelics and Drug Studies
- Laser Applications in Dentistry and Medicine
- Gut microbiota and health
- Erosion and Abrasive Machining
- High-Temperature Coating Behaviors
- Additive Manufacturing and 3D Printing Technologies
- IL-33, ST2, and ILC Pathways
University of Freiburg
2016-2025
University Medical Center Freiburg
2013-2023
Poliklinik für Zahnerhaltung und Parodontologie
2022
Zentrum für Zahn-, Mund- und Kieferheilkunde Poliklinik für Zahnerhaltung und Parodontologie
2015-2019
Institute of Medical Microbiology and Hygiene
2013
University of Bonn
2005
Eastman Dental Hospital
2005
Ghent University
2005
Abstract Aim To evaluate the effectiveness of hand and rotary instrumentation for removal vertically compacted Epiphany gutta‐percha during retreatment. Methodology Sixty extracted single‐rooted maxillary central incisors were enlarged to size 40 using FlexMaster instruments. The teeth randomly divided into four groups 15 specimens each. canals two obturated Epiphany. others filled with AH Plus sealer. One group one was reinstrumented Gates Glidden burs Hedström files. In other groups,...
Abstract Aim To determine the influence of solvents on gutta‐percha and sealer remaining root canal walls in dentinal tubules. Methodology The canals 70 teeth were prepared chemomechanically to apical size 40. In group 1 ( n = 10; control group), remained unfilled. groups 2–4 20 each), filled using lateral compaction with sealer. Removal fillings was undertaken after 2 weeks Gates Glidden burs hand files without solvent (group 2), eucalyptol (60 μL; 3) chloroform 4) 50. After further...
To determine the antibacterial effect of photodynamic Therapy on Enterococcus faecalis (E. faecalis) biofilms in experimentally infected human root canals primary infections and endodontic retreatments. One hundred sixty single-rooted extracted teeth with one canal were prepared using ProTaper instruments. Seventy specimens left without filling autoclaved. The another 70 filled Thermafil AH Plus fillings removed after 24 hours D files plasma sterilized. a clinical isolate E. for 72 hours....
Abstract Caries is associated with shifts of microbiota in dental biofilms and primarily driven by frequent sucrose consumption. Data on environmentally induced vivo are scarce therefore we investigated the influence consumption oral biofilm. Splint systems containing enamel slabs were worn for 3 × 7 days 7-day intervals to obtain biofilm samples. After a three-month dietary change sucking 10 g per day addition regular diet, was obtained again at end second phase. The analysed using Illumina...
The "leaky gut" syndrome describes a damaged (leaky) intestinal mucosa and is considered serious contributor to numerous chronic diseases. Chronic inflammatory bowel diseases (IBD) are particularly associated with the syndrome, but also allergies, autoimmune or neurological disorders. We developed complex in vitro inflammation-triggered triple-culture model using 21-day-differentiated human Caco-2 epithelial cells HT29-MTX-E12 mucus-producing goblet (90:10 ratio) close contact differentiated...
Abstract Aim To compare the accuracy of two electronic apex locators (EALs) in same teeth vivo . Methodology The working lengths 20 with a single canal were determined different EALs (Root ZX; J. Morita Corporation, Tokyo, Japan and Raypex ® 5 VDW, Munich, Germany) before extraction. When first EAL was used files advanced until display indicated ‘apical constriction’. then fixed removable replaceable light curing composite patterns. procedure repeated tooth second file. extracted apical 4 mm...
To evaluate whether artificial resin teeth could replace extracted human in pre-clinical endodontic training and if this teaching approach influences the outcome of root canal treatment on patients.In a course, students group 1 (n = 44) performed simulated exercises four plastic blocks three teeth. Students 2 45) their (Real-T Endo, Acadental, Lenexa, KS, USA). Both groups first treatments patients following term. Radiographs taken during were used for evaluation outcome. Distances between...
Abstract This experimental phantom study investigates current standard of care protocols in cone beam computed tomography (CBCT), energy-integrating-detector (EID) CT, and photon-counting-detector (PCD) CT regarding their potential delineation dental root canals. Artificial accessory canals (diameters: 1000, 600, 400, 300 200 μm) were drilled into three bovine teeth mounted on a rib as jaw substitute. The was scanned two CBCTs, EID-CTs PCD-CT using clinical protocols. Scans from micro-CT...
Thank you for your interest and thoughtful comment on our paper “Guided Plasma Application in Dentistry—An Alternative to Antibiotic Therapy” [...]
Caries development is associated with shifts in the oral biofilm microbiota and primarily linked to frequent simple carbohydrate consumption. Different nutritional ingredients can either promote or prevent caries development. To investigate effects of selected on situ, 11 study participants underwent 3-month-long dietary phases intake a regular diet (PI), additional sucrose (PII), milk yoghurt (PIII), rich fiber (PIV) then returned their (PV). Oral was sampled analyzed applying 16S rRNA...
The aim of this study was to investigate the effectiveness antimicrobial photodynamic therapy (APDT) using visible light together with water-filtered infrared-A (VIS+wIRA) eradicate single species planktonic bacteria and micro-organisms during initial oral bacterial colonization in situ. A broadband VIS+wIRA radiator a spectrum range 580-1400 nm used for irradiation. Toluidine blue (TB) utilized as photosensitizer at concentrations 5, 10, 25 50 µg ml(-1). unweighted (absolute) irradiance 200...
Cold atmospheric plasma (CAP) is a promising alternative to antibiotics and chemical substances in dentistry that can reduce the risk of unwanted side effects bacterial resistance. AmbiJet device ignite deliver directly site action for maximum effectiveness. The aim study was investigate its antimicrobial efficacy possible development effect tested under aerobic anaerobic conditions on bacteria (five aerobic, three (Gram +/−)) are relevant dentistry. application times varied from 1 7 min....
Abstract Aim To investigate whether the preclinical application of an electronic root canal length measurement device ( ERCLMD ) leads to more accurate working WL determinations in a endodontic course and if this exercise effects technical quality procedures when treatments are performed on patients for first time. Methodology Root by two consecutive groups third year students (group 1: n = 39, group 2: 44) were compared following term. Two different teaching models applied course. 1 was...
To compare ex vivo an experimental setup consisting of electronic apex locator (EAL) and endodontic motor with established product (Tri Auto ZX) for accuracy length control during root canal treatment three different types files.An porous spongy material electrolyte was used. Sixty anterior teeth were randomly assigned to six groups. Access cavities prepared. During treatment, constant monitoring performed either the Tri ZX or Raypex5 attached (Endo IT professional) using ProTaper, M(two)...