Dawid L. Staudacher
A5058003614- Mechanical Circulatory Support Devices
- Cardiac Arrest and Resuscitation
- Cardiac Structural Anomalies and Repair
- Respiratory Support and Mechanisms
- Intensive Care Unit Cognitive Disorders
- COVID-19 Clinical Research Studies
- Heart Failure Treatment and Management
- Long-Term Effects of COVID-19
- Sepsis Diagnosis and Treatment
- Acute Myocardial Infarction Research
- Anesthesia and Sedative Agents
- Cardiac Ischemia and Reperfusion
- Venous Thromboembolism Diagnosis and Management
- Anesthesia and Neurotoxicity Research
- Atrial Fibrillation Management and Outcomes
- Cardiac pacing and defibrillation studies
- Central Venous Catheters and Hemodialysis
- Hemodynamic Monitoring and Therapy
- SARS-CoV-2 and COVID-19 Research
- Cardiac electrophysiology and arrhythmias
- Cardiac Valve Diseases and Treatments
- Cardiac Imaging and Diagnostics
- Coronary Interventions and Diagnostics
- Antiplatelet Therapy and Cardiovascular Diseases
- Infective Endocarditis Diagnosis and Management
University of Freiburg
2016-2025
University Medical Center Freiburg
2017-2025
Universitäts-Herzzentrum Freiburg-Bad Krozingen
2013-2022
Carmel Medical Center
2006-2011
Technion – Israel Institute of Technology
2005-2011
Medical University of Vienna
2006-2009
Venoarterial extracorporeal membrane oxygenation (VA-ECMO) support under cardiopulmonary resuscitation (eCPR) is the last option and may be offered to selected patients. Several factors predict outcome in these patients, including initial heart rhythm, comorbidities, bystander (CPR). We evaluated outcomes of all VA-ECMO patients treated within 5 years at our center respect low-flow duration during CPR.We report retrospective registry data on with eCPR a university hospital between October...
BackgroundCoronavirus disease 2019 (COVID-19) is associated with a high burden 10% of confirmed cases progressing towards critical illness. Nevertheless, the course and predictors mortality in critically ill patients are poorly understood.MethodsFollowing developments ICUs regions experiencing early inception pandemic, European-based, international RIsk Stratification COVID-19 Intensive Care Unit (RISC-19-ICU) registry was created to provide near real-time assessment developing illness due...
We sought to clarify the benefit of cytokine adsorption in patients with COVID-19 supported venovenous extracorporeal membrane oxygenation (ECMO).We did a single-centre, open-label, randomised, controlled trial investigate adult severe pneumonia requiring ECMO. Patients selected for ECMO at Freiburg University Medical Center (Freiburg, Germany) were randomly assigned (1:1) receive using CytoSorb device or not. Randomisation was computer-generated, allocation concealed by opaque, sequentially...
The novel coronavirus SARS-CoV-2 and the resulting disease COVID-19 causes pulmonary failure including severe courses requiring venovenous extracorporeal membrane oxygenation (V-V ECMO). Coagulopathy is a known complication of leading to thrombotic events embolism. It unclear if coagulopathy also increases circuit complications ECMO. Aim present study therefor was investigate rate V-V ECMO in COVID-19. We conducted retrospective registry all patients on treated at our centre between 01/2018...
SARS-CoV2 can cause pulmonary failure requiring prolonged invasive mechanical ventilation (MV). Lung protective strategies are recommended in order to minimize ventilator induced lung injury. Whether patients with COVID-19 have the same risk for complications including barotrauma is still unknown. Therefore, we investigated pneumonia MV.All meeting diagnosis criteria ARDS according Berlin Definition, PCR positive infection and ventilation, defined as ≥2 days, treated at our referral center...
Abstract Continuously emerging variants of concern (VOCs) sustain the SARS-CoV-2 pandemic. The Omicron/B.1.1.529 VOC harbours multiple mutations in spike protein associated with high infectivity and efficient evasion from humoral immunity induced by previous infection or vaccination. By performing in-depth comparisons SARS-CoV-2-specific T-cell epitope repertoire after messenger RNA vaccination, we demonstrate that spike-derived epitopes were not dominantly targeted convalescent individuals...
Prone positioning (PP) reduces mortality of patients with acute respiratory distress syndrome (ARDS). The potential benefit prone maneuvers during venovenous extracorporeal membrane oxygenation (ECMO) is unknown. aim this study was to evaluate the association between use support and ICU in a pooled population from previous European cohort studies.We performed individual patient data analysis studies which compared treated ECMO (Prone group) "conventional" management (Supine severe ARDS.889...
ABSTRACT Introduction Veno‐venous extracorporeal membrane oxygenation (V‐V ECMO) is increasingly used in the treatment of severe respiratory failure. Despite a significant increase worldwide use lung assist devices recirculation remains common complication and associated with reduced effectiveness ECMO support increased hemolysis. In this observational study we aimed to investigate impact cannula configuration flow on recirculation. Materials Methods An retrospective was performed, which...
Aims: Several scoring systems have been introduced for prognostication after initiating venoarterial extracorporeal membrane oxygenation (VA-ECMO) therapy. However, static scores offer limited guidance once VA-ECMO is implanted, although continued allocation of healthcare resources critical. Patients requiring support are extremely unstable, with minimal heart function and multi-organ failure in most cases. The aim the present study was to develop validate a dynamic prognostic model patients...
Prone positioning (PP) has shown to improve survival in patients with severe acute respiratory distress syndrome (ARDS). To this point, it is unclear if PP also beneficial for ARDS treated veno-venous extracorporeal membrane oxygenation (VV ECMO) support. We report retrospective data of a single-centre registry requiring VV ECMO support between October 2010 and May 2018. Patients were allocated the group was performed during treatment or supine group. weaning success hospital analysed before...
Abstract Background A central element in the management of cardiogenic shock (CS) comprises mechanical circulatory support (MCS) systems to maintain cardiac output (CO). This study aims quantify incidence, outcome and influence MCS CS over last decade. Methods All patients hospitalized with a tertiary university hospital Germany between 2007 2017 were identified utilizing international coding system ICD-10 code R57.0. Application was via German procedure classification codes (OPS). Results...
Accurate risk stratification of critically ill patients with coronavirus disease 2019 (COVID-19) is essential for optimizing resource allocation, delivering targeted interventions, and maximizing patient survival probability. Machine learning (ML) techniques are attracting increased interest the development prediction models as they excel in analysis complex signals data-rich environments such critical care.We retrieved data on COVID-19 admitted to an intensive care unit (ICU) between March...
Severe COVID-19 induced acute respiratory distress syndrome (ARDS) often requires extracorporeal membrane oxygenation (ECMO). Recent German health insurance data revealed low ICU survival rates. Patient characteristics and experience of the ECMO center may determine intensive care unit (ICU) survival. The current study aimed to identify factors affecting patients.673 ARDS patients treated in 26 centers between January 1st 2020 March 22nd 2021 were included. Data on clinical characteristics,...
Sevoflurane sample data in a standard single patient ICU room, VieCuri Medical Centre. Physical of the room: 52 m3, air refreshing rate minimum 6/hr
The novel coronavirus severe acute respiratory syndrome 2 is infecting hundreds of thousands humans around the globe. disease 2019 (COVID-19) known to generate mild as well critical courses. Complications on intensive care units include distress syndrome, cardiac, and kidney injury shock. Here, we present first case report a successful treatment COVID-19 patient presenting with adult plus refractory combined cardiogenic vasoplegic shock, which could be successfully stabilized after...
The role of veno-venous extracorporeal membrane oxygenation therapy (V-V ECMO) in severe COVID-19 acute respiratory distress syndrome (ARDS) is still under debate and conclusive data from large cohorts are scarce. Furthermore, criteria for the selection patients that benefit most this highly invasive resource-demanding yet to be defined. In study, we assess survival an international multicenter cohort treated with V-V ECMO evaluate performance several clinical scores predict 30-day survival....