- Kawasaki Disease and Coronary Complications
- Coronary Artery Anomalies
- Respiratory viral infections research
- Autoimmune and Inflammatory Disorders Research
- COVID-19 Clinical Research Studies
- Systemic Lupus Erythematosus Research
- Streptococcal Infections and Treatments
- Liver Disease Diagnosis and Treatment
- Hepatitis C virus research
- Long-Term Effects of COVID-19
- Orthopedic Infections and Treatments
- Rheumatoid Arthritis Research and Therapies
- Infectious Diseases and Tuberculosis
- Hepatitis B Virus Studies
- Vasculitis and related conditions
- Hematological disorders and diagnostics
- Inflammatory Myopathies and Dermatomyositis
- SARS-CoV-2 and COVID-19 Research
- Dermatological and COVID-19 studies
- Renal Diseases and Glomerulopathies
- Pneumonia and Respiratory Infections
- Cardiovascular Issues in Pregnancy
- Emergency and Acute Care Studies
- Neonatal and Maternal Infections
- Inflammasome and immune disorders
University of Florence
2009-2025
Meyer Children's Hospital
2016-2025
Istituti di Ricovero e Cura a Carattere Scientifico
2023-2025
The European Academy of Gynaecological Surgery
2022-2024
Department of Medical Sciences
2018-2022
Temple Street Children's University Hospital
2019-2021
Azienda Ospedaliero Universitaria Maggiore della Carita
2019
Università degli Studi del Piemonte Orientale “Amedeo Avogadro”
2019
Stony Brook University
2019
Azienda Ospedaliero-Universitaria Careggi
2017
Introduction: Human Bocavirus (HBoV) is mainly associated with respiratory tract infections. However, its role as pathogen not fully understood for a high co-infection rate in symptomatic patients and significant HBoV detection asymptomatic subjects. This study aimed to describe large cohort of children infection compare mono-infection co-infections. Methods: We retrospectively reviewed data from 165 admitted Meyer Children’s Hospital IRCCS March 2022 2023 the diagnosis infection, detected...
Sevoflurane sample data in a standard single patient ICU room, VieCuri Medical Centre. Physical of the room: 52 m3, air refreshing rate minimum 6/hr
Influenza is the most frequent cause of acute upper respiratory tract infections during winter season. Although rare, neurological manifestations are known to occur influenza infection and approximatively three-quarters cases in children. In this study, we aimed characterize burden clinical spectrum influenza-associated encephalopathy encephalitis children admitted at a tertiary pediatric hospital Italy over two seasons (2017-2019).We retrospectively analyzed clinical, laboratory,...
The first pediatric study demonstrating significantly higher positivity rate of nasal (mid-turbinate) swab testing over oropharyngeal in detecting SARS-CoV-2 (Fisher exact test 0.046, Cohen K 0.43, confidence interval 95%, 0.014–0.855). Benefits might include lower collection-related hazard for healthcare workers. We recommend it as preferred choice swab-based children.
Benign acute childhood myositis (BACM) is a self-limited illness, and viral infections mainly cause it. Clinical laboratory alterations usually normalize rapidly; generally, the only medical intervention required supportive (hydration analgesic medication). The low awareness about BACM often led to delayed diagnosis unneeded ancillary investigations. This study aims better characterize clinical features of improve diagnostic process inpatient outpatient management. We conducted retrospective...
Introduction Avoiding over-investigation and overtreatment in health care is a challenge for clinicians across the world, prompting international Choosing Wisely campaign. Lists of recommendations regarding medical overactivity are helpful tools to guide quality improvement initiatives. We aimed identify most frequent important clinical challenges related pediatric Europe Japan. Based on results, we aim establish (European) list recommendations. Methods In an online survey, responsible child...
BackgroundVery few studies describe factors associated with COVID-19 diagnosis in children.AimWe here characteristics and risk for children tested 20 paediatric centres across Italy.MethodsWe included cases aged 0-18 years between 23 February 24 May 2020. Our primary analysis focused on because of symptoms/signs suggestive COVID-19.ResultsAmong 2,494 tested, 2,148 (86.1%) had symptoms COVID-19. Clinical presentation confirmed besides fever (82.4%) respiratory signs or (60.4%) also...
Few data are currently available for Kawasaki disease (KD) below 12 months especially in Caucasians. This study aims to analyze clinical and laboratory features of KD among an Italian cohort infants. A retrospective chart review children aged less than 1 year at time onset between January 2008–December 2017 was performed. Clinical data, parameters, instrumental findings, treatment outcome were collected a customized database. Among 113 patients, 32 (28.3%) younger year. Nineteen patients 6...
This study aimed to evaluate the type and severity of neurological involvement in children with SARS-CoV-2 infection or multisystem inflammatory syndrome (MIS-C) compare these findings between two groups. Children hospitalized diagnosis COVID-19 MIS-C at Meyer Children's Hospital February 2020 June 2022 were retrospectively studied. One hundred twenty-two patients enrolled, 95 group 27 group. In group, impairment consciousness was found 67.4% patients, headache 18.9% about 16.8% experienced...
A recombinant vaccine is approved to prevent herpes zoster (HZ) in adults ≥50 years and immunocompromised individuals ≥19 years. However, children, the live attenuated remains only prevention strategy against varicella virus (VZV), with one trial evaluating safety immunogenicity of GlaxoSmithKline's HZ subunit candidate children. To estimate VZV burden our third level pediatric hospital identify high-risk groups for its occurrence complications explore need an inactivated vaccine. We...
<title>Abstract</title> Background Acute mastoiditis (AM) is the most common complication of acute otitis media (AOM) and could lead to serious complications if not diagnosed early treated appropriately. Nowadays, there no definitive consensus about diagnostic algorithm optimal therapeutic management for patients with AM. The purpose this study analyze children admitted AM complicated (CAM) in a referral children's hospital, evaluating differences clinical presentation outline pathway....
To investigate the prevalence and features of asymptomatic pulmonary involvement in juvenile dermatomyositis (JDM).Twelve JDM patients underwent function tests at baseline, 12 24 months. Disease activity, duration, serum lactate dehydrogenase (LDH) values antinuclear antibody (ANA) titres were also evaluated.Five showed lung impairment baseline four Forced expiratory volume 1s, forced vital capacity (FVC), carbon monoxide diffusing (DLCO) alveolar most frequently altered variables,...
Pleuro-pulmonary involvement has been well recognized in adults affected with systemic lupus erythematosus (SLE), but few studies have carried out children. A longitudinal study on a group of 15 children juvenile SLE (JSLE), asymptomatic for lung disease, was performed, and the prevalence features respiratory function alterations, over period 12 months, were analysed. Moreover, possible correlation between any pulmonary test (PFT) disease duration, activity, visceral immunological pattern...