A5007796760- Parasites and Host Interactions
- Parasite Biology and Host Interactions
- Helminth infection and control
- Parasitic Diseases Research and Treatment
- Malaria Research and Control
- Mosquito-borne diseases and control
- Parasitic infections in humans and animals
- Global Maternal and Child Health
- Parasitic Infections and Diagnostics
- Research on Leishmaniasis Studies
- Trypanosoma species research and implications
- Amoebic Infections and Treatments
- COVID-19 Clinical Research Studies
- Travel-related health issues
- SARS-CoV-2 and COVID-19 Research
- Global Health and Surgery
- Child Nutrition and Water Access
- Viral Infections and Vectors
- Global Health Workforce Issues
- Tuberculosis Research and Epidemiology
- COVID-19 diagnosis using AI
- Congenital Anomalies and Fetal Surgery
- SARS-CoV-2 detection and testing
- Fungal Infections and Studies
- Dermatological diseases and infestations
Ospedale Sacro Cuore Don Calabria
2016-2025
Istituti di Ricovero e Cura a Carattere Scientifico
2018-2025
National Institute of Infectious Diseases
2023
Nagoya University
2023
University of Modena and Reggio Emilia
2023
Azienda Ospedaliero-Universitaria di Modena
2023
Tokai University
2023
Renji Hospital
2022
Shanghai Jiao Tong University
2022
Universidad de Las Américas
2022
Strongyloidiasis is a common neglected tropical disease in and sub-tropical climatic zones. At the worldwide level, there high uncertainty about strongyloidiasis burden. This represents an important knowledge gap since it affects planning of interventions to reduce burden endemic countries. study aimed estimate global prevalence. A literature review was performed obtain prevalence data from countries at level 1990 2016. For each study, true population calculated by accounting for specificity...
Background The diagnosis of Strongyloides stercoralis (S. stercoralis) infection is hampered by the suboptimal sensitivity fecal-based tests. Serological methods are believed to be more sensitive, although assessing their accuracy difficult because lack a reference ("gold") standard. Methods and specificity 5 serologic tests for S. (in-house IFAT, NIE-ELISA NIE-LIPS commercially available Bordier-ELISA IVD-ELISA) were assessed on 399 cryopreserved serum samples. Accuracy was measured using...
Soil-transmitted helminth (STH) infections are the most widespread of neglected tropical diseases, primarily affecting marginalized populations in low- and middle-income countries. More than one billion people currently infected with STHs. For control these infections, World Health Organization (WHO) recommends an integrated approach, which includes access to appropriate sanitation, hygiene education, preventive chemotherapy (i.e., large-scale, periodic distribution anthelmintic drugs)....
Although antibody levels progressively decrease following SARS-CoV-2 infection, the immune memory persists for months. Thus, individuals who naturally contracted are expected to develop a more rapid and sustained response COVID-19 vaccines than naïve individuals. In this study, we analyzed dynamics of BNT162b2 mRNA vaccine in six healthcare workers March 2020, comparison nine control subjects without previous infection. The was well tolerated by both groups, with no significant difference...
Few population-based studies provide epidemiological data on infective endocarditis (IE). Aim of the study is to analyze incidence and outcomes IE in Veneto Region (North-Eastern Italy). Residents with a first hospitalization for 2000-2008 were extracted from discharge linked mortality records estimate 365-days survival. Etiology was retrieved subsets this cohort by codes linkage microbiological database. Risk factors assessed through logistic regression. 1,863 subjects hospitalized IE,...
Background Traditional faecal-based methods have poor sensitivity for the detection of S. stercoralis, therefore are inadequate post-treatment evaluation infected patients who should be carefully monitored to exclude persistence infection. In a previous study, we demonstrated high accuracy five serology tests screening and diagnosis strongyloidiasis. Aim this study is evaluate performance same follow up with stercoralis. Methods Retrospective on anonymized, cryo-preserved samples available...
Schistosomiasis is a neglected infection affecting millions of people, mostly living in sub-Saharan Africa. Morbidity and mortality due to chronic are relevant, although schistosomiasis often clinically silent. Different diagnostic tests have been implemented order improve screening diagnosis, that traditionally rely on parasitological with low sensitivity. Aim this study was evaluate the accuracy different for African migrants, non endemic setting.A retrospective conducted 373 patients...
High concentrations of ivermectin demonstrated antiviral activity against SARS-CoV-2 in vitro. The aim this study was to assess the safety and efficacy high-dose reducing viral load individuals with early infection. This a randomised, double-blind, multicentre, phase II, dose-finding, proof-of-concept clinical trial. Participants were adults recently diagnosed asymptomatic/oligosymptomatic Exclusion criteria were: pregnant or lactating women; CNS disease; dialysis; severe medical condition...
Background Strongyloidiasis may cause a life-threatening disease in immunosuppressed patients. This can only be prevented by effective cure of chronic infections. Direct parasitologic exams are not sensitive enough to prove if negative. We used an indirect immune fluorescent antibody test (IFAT) along with direct methods for patient inclusion and efficacy assessment. Methodology/Principal Findings Prospective, randomized, open label, phase III trial conducted at the Centre Tropical Diseases...
Strongyloidiasis is a disease caused by an infection with soil-transmitted helminth that affects, according to largely varying estimates, between 30 million and 370 people worldwide [1,2]. Not officially listed as neglected tropical (NTD), strongyloidiasis stands out particularly overlooked [3]. Indeed, there paucity of research public health efforts pertaining strongyloidiasis. Hence, clinical, diagnostic, epidemiologic, treatment, control aspects are not adequately addressed allow for...
Strongyloidiasis is a neglected tropical disease caused by the human infective nematodes Strongyloides stercoralis, fuelleborni and kellyi. Previous large-scale studies exploring genetic diversity of this important genus have focused on Southeast Asia, with small number isolates from USA, Switzerland, Australia several African countries having been genotyped. Consequently, little known about global distribution geographic sub-variants these that exists within generally. We extracted DNA...