Alessandra C. Goulart
- Nutritional Studies and Diet
- Acute Ischemic Stroke Management
- Blood Pressure and Hypertension Studies
- Migraine and Headache Studies
- Cardiovascular Health and Disease Prevention
- Thyroid Disorders and Treatments
- Obesity, Physical Activity, Diet
- Cardiovascular Health and Risk Factors
- Health disparities and outcomes
- Global Public Health Policies and Epidemiology
- Diabetes, Cardiovascular Risks, and Lipoproteins
- Heart Rate Variability and Autonomic Control
- Liver Disease Diagnosis and Treatment
- Cardiovascular Disease and Adiposity
- Climate Change and Health Impacts
- Global Health Care Issues
- Global Maternal and Child Health
- Health Systems, Economic Evaluations, Quality of Life
- Cerebrovascular and Carotid Artery Diseases
- Stroke Rehabilitation and Recovery
- Vitamin D Research Studies
- Acute Myocardial Infarction Research
- Cardiac Health and Mental Health
- Diet, Metabolism, and Disease
- Coffee research and impacts
Hospital Universitário da Universidade de São Paulo
2016-2025
Universidade de São Paulo
2016-2025
Hospital das Clínicas da Faculdade de Medicina da Universidade de São Paulo
2011-2024
Departamento de Epidemiología
2024
Instituto de Saúde
2024
Universidade Cidade de São Paulo
2014-2024
Universidade Brasil
2011-2023
Hospital Sírio-Libanês
2020-2023
Institute for Health Metrics and Evaluation
2017-2023
Hospital de Clínicas
2011-2023
<h2>Summary</h2><h3>Background</h3> Suboptimal diet is an important preventable risk factor for non-communicable diseases (NCDs); however, its impact on the burden of NCDs has not been systematically evaluated. This study aimed to evaluate consumption major foods and nutrients across 195 countries quantify their suboptimal intake NCD mortality morbidity. <h3>Methods</h3> By use a comparative assessment approach, we estimated proportion disease-specific attributable each dietary (also...
Stroke is a leading cause of mortality and disability worldwide the economic costs treatment post-stroke care are substantial. The Global Burden Diseases, Injuries, Risk Factors Study (GBD) provides systematic, comparable method quantifying health loss by disease, age, sex, year, location to provide information systems policy makers on more than 300 causes disease injury, including stroke. results presented here estimates burden due overall stroke ischaemic haemorrhagic from GBD 2016.
Comparable data on the global and country-specific burden of neurological disorders their trends are crucial for health-care planning resource allocation. The Global Burden Diseases, Injuries, Risk Factors (GBD) Study provides such information but does not routinely aggregate results that interest to clinicians specialising in conditions. In this systematic analysis, we quantified disease due 2015 its relationship with country development level.We estimated prevalence, mortality,...
<h2>Summary</h2><h3>Background</h3> Through the Global Burden of Diseases, Injuries, and Risk Factors (GBD) studies, headache has emerged as a major global public health concern. We aimed to use data from GBD 2016 study provide new estimates for prevalence years life lived with disability (YLDs) migraine tension-type present methods results in an accessible way clinicians researchers disorders. <h3>Methods</h3> Data were derived population-based cross-sectional surveys on headache....
Transcranial direct current stimulation (tDCS) trials for major depressive disorder (MDD) have shown positive but mixed results.To assess the combined safety and efficacy of tDCS vs a common pharmacological treatment (sertraline hydrochloride, 50 mg/d).Double-blind, controlled trial. Participants were randomized using 2 × factorial design to sertraline/placebo active/sham tDCS.Outpatient, single-center academic setting in São Paulo, Brazil.One hundred twenty antidepressant-free patients with...
BackgroundAlthough the burden of influenza is often discussed in context historical pandemics and threat future pandemics, every year a substantial lower respiratory tract infections (LRTIs) other conditions (like chronic obstructive pulmonary disease) are attributable to seasonal influenza. The Global Burden Disease Study (GBD) 2017 systematic scientific effort quantify health loss associated with comprehensive set diseases disabilities. In this Article, we focus on LRTIs that can be...
Political, economic, and epidemiological changes in Brazil have affected health the system. We used Global Burden of Disease Study 2016 (GBD 2016) results to understand changing patterns inform policy responses.
There is scarce data about prevalence of stroke in Brazil. The National Health Survey (PNS) a community-based epidemiological survey, with nationally representative sample to assess the absolute numbers respective rates and post-stroke disabilities. It was estimated 2,231.000 568,000 cases severe point prevalences 1.6% 1.4% men women, respectively. disabilities were 29.5% for 21.5% women. Stroke increased aging, low education level, among people living urban areas no difference according...
Many countries have shown marked declines in diarrhoeal disease mortality among children younger than 5 years. With this analysis, we provide updated results on years from the Global Burden of Diseases, Injuries, and Risk Factors Study 2017 (GBD 2017) use study's comparative risk assessment to quantify trends effects factors, interventions, broader sociodemographic development changes 195 territories 1990 2017.This analysis for GBD had three main components. Diarrhoea was modelled using...
Este artigo descreve os exames clínicos realizados no Estudo Longitudinal de Saúde do Adulto (ELSA-Brasil). Alguns deles (antropometria, pressão arterial e índice tornozelo-braquial) já têm uso clínico consolidado. Outros, como a velocidade onda pulso, variabilidade da frequência cardíaca medida espessura médio-intimal carótidas, carecem valor referência na população brasileira não doente podem constituir preditores importantes desfechos cardiovasculares. A após manobra postural foi incluída...
Decreased heart rate variability (HRV) is a cardiovascular predictor of mortality. Recent debate has focused on whether reductions in HRV major depressive disorder (MDD) are consequence the or pharmacotherapy. Here we report impact transcranial direct current stimulation (tDCS), non-pharmacological intervention, vs. sertraline to further investigate this issue. The employed design was double-blind, randomized, factorial, placebo-controlled trial. One hundred and eighteen moderate-to-severe,...
O Estudo Longitudinal de Saúde do Adulto (ELSA-Brasil) é um estudo coorte composto 15.105 adultos acompanhados para avaliar o desenvolvimento doenças crônicas, especialmente diabetes e doença cardiovascular. Seu porte, natureza multicêntrica diversidade medidas exigiram mecanismos ágeis efetivos garantia controle qualidade. Entre as atividades qualidade (aquelas desenvolvidas antes iniciar a coleta dados), destacam-se: seleção criteriosa dos instrumentos pesquisa, treinamento certificação...
<h3>Background</h3> Post-stroke depression is a disabling condition occurring in about one-third of patients with stroke. Pharmacological treatments have limited efficacy and important side effects. Recently, transcranial direct current stimulation (tDCS) has shown treating depression. This study aimed to assess the safety tDCS for post-stroke <h3>Methods</h3> 48 antidepressant-free were randomised into two groups (active sham tDCS). 12 30 min sessions 2 mA anodal left/cathodal right...
The epidemiological transition of non-communicable diseases replacing infectious as the main contributors to disease burden has been well documented in global health literature. Less focus, however, given relationship between sociodemographic changes and injury. aim this study was examine association disability-adjusted life years (DALYs) from injury for 195 countries territories at different levels along development spectrum 1990 2017 based on Global Burden Disease (GBD) estimates.Injury...
The EAT-Lancet Commission has proposed a model diet to improve the health of human beings and that planet. Recently, we Planetary Health Diet Index (PHDI) assess adherence population this diet. In study, aimed evaluate PHDI obesity outcomes using baseline data from 14,515 participants in Brazilian Longitudinal Study Adult (ELSA-Brasil). dietary were assessed 114-item FFQ. Body mass index (BMI) waist circumference (WC) both used continuously categorized. Linear multinomial regression models...
Post-stroke depression (PSD) affects approximately 40% of stroke survivors, with cognitive deficits being frequently observed. Transcranial Direct Current Stimulation (tDCS) has shown promise in improving performance patients. We explored the effects tDCS on PSD. An exploratory analysis was conducted 48 patients from a double-blinded, sham-controlled, randomized clinical trial that investigated for treating A neuropsychological battery applied at baseline and endpoint. assessed three key...
Background Transcranial direct current stimulation (tDCS) is a promising nonpharmacological therapy for major depression. In the Sertraline versus Electrical Current Therapy Treating Depression Clinical Trial (SELECT-TDCS) trial, phase-I (Brunoni et al., JAMA Psychiatry, 2013) we found that tDCS effective acute episode. Here, describe effects during phases II (crossover) and III (follow-up) of this trial (NCTs: 01149889 01149213). Methods Phase (n = 25) was open-label, crossover phase in...
Objective— There is little information about how much traditional cardiovascular risk factors explain common carotid artery intima-media thickness (CCA-IMT) variance. We aimed to study which extent CCA-IMT values are determined by and commonly used measurements of blood pressure, glucose metabolism, lipid profile, adiposity contribute the most this determination in Brazilian Longitudinal Study Adult Health (ELSA-Brasil) cohort baseline. Approach Results— analyzed 9792 individuals with...