- Dermatology and Skin Diseases
- Acne and Rosacea Treatments and Effects
- Nonmelanoma Skin Cancer Studies
- Nail Diseases and Treatments
- Asthma and respiratory diseases
- Cutaneous Melanoma Detection and Management
- Climate Change and Health Impacts
- Cutaneous lymphoproliferative disorders research
- Global Health Care Issues
- Wound Healing and Treatments
- Allergic Rhinitis and Sensitization
- Pharmacological Effects of Natural Compounds
- Contact Dermatitis and Allergies
- Urticaria and Related Conditions
- Health disparities and outcomes
- Global Maternal and Child Health
- Dermatological diseases and infestations
- Child Nutrition and Water Access
- Food Allergy and Anaphylaxis Research
- Skin Protection and Aging
- Psoriasis: Treatment and Pathogenesis
- Gut microbiota and health
- Hair Growth and Disorders
- Global Public Health Policies and Epidemiology
- Diabetic Foot Ulcer Assessment and Management
Case Western Reserve University
2022-2025
University School
2022-2025
AbbVie (United States)
2023-2024
University Hospitals of Cleveland
2024
Institute for Health Metrics and Evaluation
2018-2024
University of Washington
2018-2024
Boston University
2013-2022
Almirall (Spain)
2020-2022
Icahn School of Medicine at Mount Sinai
2022
Baylor University Medical Center
2021-2022
Background: Psoriasis is a common, chronic, inflammatory, debilitating, systemic disease with great impact on healthcare systems worldwide. As targeted therapies have transformed the therapeutic landscape, updated estimates of Global Burden Disease (GBD) imposed by psoriasis are necessary in order to evaluate effects past health care policies and orient inform new national international strategies. Methods: Data were extracted from GBD 2019 study, which collates systematic review relevant...
Masks are essential for COVID-19 prevention, but recently they were suggested to modify cutaneous facial microenvironment and trigger dermatoses. To evaluate mask-related rosacea acne (maskne) in untreated patients during lockdown. In this multi-center, real-life, observational prospective study, we enrolled stable, that wore masks lockdown at least 6 h/day. They underwent two teledermatological consultations, the baseline after weeks. Clinical, pharmacological, psychological data recorded....
Sustainable Development Goal (SDG) 3 aims to "ensure healthy lives and promote well-being for all at ages". While a substantial effort has been made quantify progress towards SDG3, less research focused on tracking spending this goal. We used estimates measure in financing the priority areas of examine association between outcomes financing, identify where resource gains are most needed achieve SDG3 indicators which data available.We estimated domestic health spending, disaggregated by...
The epidemiological transition of non-communicable diseases replacing infectious as the main contributors to disease burden has been well documented in global health literature. Less focus, however, given relationship between sociodemographic changes and injury. aim this study was examine association disability-adjusted life years (DALYs) from injury for 195 countries territories at different levels along development spectrum 1990 2017 based on Global Burden Disease (GBD) estimates.Injury...
<h3>Importance</h3> Skin and subcutaneous diseases affect the health of millions individuals in US. Data are needed that highlight geographic trends variations skin disease burden across country to guide care decision-making. <h3>Objective</h3> To characterize tissue US from 1990 2017. <h3>Design, Setting, Participants</h3> For this cohort study, data were obtained Global Burden Disease (GBD), a study with an online database incorporates current previous epidemiological studies burden, GBD...
Atopic dermatitis is a chronic inflammatory disease characterized by increased itch, skin pain, poor sleep quality, and other symptoms that negatively affect patient quality of life. Upadacitinib, an oral selective Janus kinase (JAK) inhibitor with greater inhibitory potency for JAK1 than JAK2, JAK3, or tyrosine 2, approved to treat moderate-to-severe atopic dermatitis. We aimed evaluate the effect upadacitinib on patient-reported outcomes over 52 weeks in adults adolescents Data from two...
Achieving the United Nations' Sustainable Development Goals remains challenging for many low- and middle-income countries (LMICs). Generative artificial intelligence (AI) offers potential to improve health care delivery access quality in LMICs. AI applications include individualizing decision support systems personalized diagnosis treatment, predicting managing epidemics, improving medical image interpretation, enhancing telemedicine, accelerating drug discovery. In addition, generative can...
Treatment for moderate-to-severe acne vulgaris relies on prolonged use of oral tetracycline-class antibiotics; however, these broad-spectrum antibiotics are often associated with off-target effects and negative gastrointestinal sequelae. Sarecycline is a narrow-spectrum antibiotic treatment option. Here, we investigated the effect sarecycline exposure, compared tetracyclines (doxycycline minocycline) upon colonic microbiota. Three in vitro models human colon were instilled either...
Minimal erythema dose (MED) remains a parameter of paramount importance to orient narrow-band (NB)-UVB phototherapy in psoriatic (PsO) patients. Recently, circadian rhythm and diet were recognized as potential MED modulators, but their mutual interaction understudied. Thus, we aimed evaluate the modulation oscillations. In first phase, cohort study was performed comparing oscillations (morning, afternoon, evening) among omnivorous patients before after cycle healthy controls. The two groups...
Vegans and vegetarians often consume foods containing photosensitizers capable of triggering phytophotodermatitis. The potential effect vegan vegetarian diets on the response psoriatic patients undergoing phototherapy is not well characterized. We assessed clinical outcomes vegan, omnivore adult band ultraviolet B (NB-UVB). In this multicenter prospective observational study, we enrolled 119 adult, patients, whom 40 were omnivores, 41 38 vegans, with indication. After determining minimum...
Alopecia areata (AA) has been associated with multiple comorbidities, yet information regarding the timing of comorbidity development after AA diagnosis is limited.