A5059081185- Healthcare Systems and Practices
- Health and Medical Studies
- Health Systems, Economic Evaluations, Quality of Life
- Global Health Care Issues
- Nutritional Studies and Diet
- Health disparities and outcomes
- Global Public Health Policies and Epidemiology
- Insurance, Mortality, Demography, Risk Management
- Clinical practice guidelines implementation
- Birth, Development, and Health
- Health, Medicine and Society
- Obesity, Physical Activity, Diet
- Chronic Disease Management Strategies
- Healthcare Policy and Management
- HIV/AIDS Research and Interventions
- Health Promotion and Cardiovascular Prevention
- Sodium Intake and Health
- Diet and metabolism studies
- Primary Care and Health Outcomes
- Blood Pressure and Hypertension Studies
- Global Cancer Incidence and Screening
- Nutrition, Genetics, and Disease
- Aging, Elder Care, and Social Issues
- School Health and Nursing Education
- Cardiovascular Health and Risk Factors
University of Lausanne
2010-2023
Centre universitaire de médecine générale et santé publique, Lausanne
2020-2023
University Hospital of Lausanne
1998-2020
Institute of Social and Preventive Medicine
2008-2019
l'Assurance Maladie
2014
Université de Sherbrooke
2014
University of Zurich
2014
Conservatoire National des Arts et Métiers
2014
Swiss School of Public Health
2010-2013
University of Duisburg-Essen
2013
Patel M (Route de Saint-Loup 4, 1290 Versoix, Switzerland), Gutzwiller F, Paccaud F and Marazzi A. A meta-analysis of acupuncture for chronic pain. International Journal Epidemiology 1989, 18: 900–906. Results 14 randomized controlled trials pain were pooled in a analysed three subgroups according to site pain; two each type trial, treatment, control, 'blindness' participating agents, trial size, journal which results published. While few individual had statistically significant results,...
Background: In humans, low socioeconomic status (SES) across the life course is associated with greater diurnal cortisol production, increased inflammatory activity and higher circulating antibodies for several pathogens, all suggesting a dampened immune response. Recent evidence suggests that DNA methylation of pro-inflammatory genes may be implicated in biological embedding social environment. Methods: The present study examines association between life-course SES candidate genes, selected...
<h3>Abstract</h3> <h3>Objective</h3> To assess the association of low socioeconomic status and risk factors for non-communicable diseases (diabetes, high alcohol intake, blood pressure, obesity, physical inactivity, smoking) with loss functioning at older ages. <h3>Design</h3> Multi-cohort population based study. <h3>Setting</h3> 37 cohort studies from 24 countries in Europe, United States, Latin America, Africa, Asia, 1990-2017. <h3>Participants</h3> 109 107 men women aged 45-90 years....
Increased renal resistive index (RRI) has been recently associated with target organ damage and cardiovascular or outcomes in patients hypertension diabetes mellitus. However, reference values the general population information on familial aggregation are largely lacking. We determined distribution of RRI, factors, heritability a population-based study. Families European ancestry were randomly selected 3 Swiss cities. Anthropometric parameters risk factors assessed. A Doppler ultrasound was...
Switzerland is a multilingual country located between Germany, France and Italy, which differ by dietary habits related outcomes. We explored differences in food consumption as well compliance to the Swiss food-based guidelines (FBDG) across German-, French-, Italian-speaking regions. The 2014-2015 nationwide cross-sectional survey was conducted among stratified random sample of 2057 adults aged 18 75 years. Trained dietitians assessed via two non-consecutive 24-h recalls using international...
Objectives. The purpose of this study was to assess the adequacy three widely used models-Lognormal, Weibull, and Gamma-for describing distribution length stay. This is a fundamental step in development outliers resistant (robust) methods for statistical analysis kind data, where main objective determine measures average total resource consumption groups patients. Current practice uses several types trimming rules, many which are based on Lognormal model, although theoretical experimental...
The enormous variation in human lifespan is part due to a myriad of sequence variants, only few which have been revealed date. Since many life-shortening events are related diseases, we developed Mendelian randomization-based method combining 58 disease-related GWA studies derive longevity priors for all HapMap SNPs. A Bayesian association scan, informed by these priors, parental age death the UK Biobank study (n=116,279) 16 independent SNPs with significant Bayes factor at 5% false...
Eighty percent of the global 17 million deaths due to cardiovascular disease (CVD) occur in low and middle income countries (LMICs). The burden CVD other noncommunicable diseases (NCDs) is expected markedly increase because aging population increasing exposure detrimental lifestyle-related risk LMICs. Interventions reduce four main risks related modifiable behaviors (tobacco use, unhealthy diet, physical activity excess alcohol consumption) are key elements for effective primary prevention...
Arginine vasopressin (AVP) has a key role in osmoregulation by facilitating water transport the collecting duct. Recent evidence suggests that AVP may have additional effects on renal function and favor cyst growth polycystic kidney disease. Whether also affects structure general population is unknown. We analyzed association of copeptin, an established surrogate for AVP, with parameters morphology multicentric population-based cohort. Participants from families European ancestry were...
To estimate the incremental cost-effectiveness of first-line pharmacotherapies (nicotine gum, patch, spray, inhaler, and bupropion) for smoking cessation across six Western countries-Canada, France, Spain, Switzerland, United States, Kingdom.A Markov-chain cohort model to simulate two cohorts smokers: (1) a reference given brief counselling by general practitioner (GP); (2) treatment plus pharmacotherapy. Effectiveness expressed as odds ratios quitting associated with pharmacotherapies....
Frailty prevalence in older adults has been reported but is largely unknown middle-aged adults. We determined the of frailty indicators among and from a general Swiss population characterized by universal health insurance coverage assessed determinants with special focus on socioeconomic status. Participants aged 50 more population-based 2006–2010 Bus Santé study were included (<mml:math xmlns:mml="http://www.w3.org/1998/Math/MathML"...
Background. Although acquired immune deficiency syndrome-associated morbidity has diminished due to excellent viral control, multimorbidity may be increasing among human immunodeficiency virus (HIV)-infected persons compared with the general population. Methods. We assessed prevalence of comorbidities and in participants Swiss HIV Cohort Study (SHCS) population-based CoLaus study primary care-based FIRE (Family Medicine ICPC-Research using Electronic Medical Records) records. The incidence...
OBJECTIVES: This study is part of a continuous evaluation the Swiss AIDS prevention strategy from 1987 through 1994. METHODS: Annual telephone surveys samples representative general population aged 17 45 years have been conducted since to monitor behavioral change. RESULTS: No major changes in level sexual activity (lifetime number partners, frequency encounters past week) or potential exposure risk HIV transmission (acquisition new steady partner during year casual partners last 6 months)...
This paper aims to examine changes in common longevity and variability of the adult life span, attempts answer whether or not compression mortality continues Switzerland years 1876-2005. The results show that negative relati
Abstract Objective To assess the iodine status of Swiss population groups and to evaluate influence iodized salt as a vector for fortification. Design The relationship between 24 h urinary Na excretions was assessed in general after correcting confounders. Single-day intakes were estimated assuming that 92 % dietary excreted urine. Usual intake distributions derived male female adjustment within-subject variability. average requirement (EAR) cut-point method applied guidance inadequacy...
Global health has attracted growing attention from academic institutions. Its emergence corresponds to the increasing interdependence that characterizes our time and provides a new worldview address challenges globally. There is still large potential better delineate limits of field, drawing on wide perspective across sciences geographical areas. As an implementation integration science, global aims primarily respond societal needs through research, education, practice. From five...