A5027895986- Folate and B Vitamins Research
- Bone health and osteoporosis research
- Nutritional Studies and Diet
- Hip and Femur Fractures
- Obesity, Physical Activity, Diet
- Lipoproteins and Cardiovascular Health
- Chronic Disease Management Strategies
- Acute Myocardial Infarction Research
- Nutrition and Health in Aging
- Birth, Development, and Health
- Cardiovascular Health and Disease Prevention
- Diabetes, Cardiovascular Risks, and Lipoproteins
- Blood Pressure and Hypertension Studies
- Diet and metabolism studies
- Health Promotion and Cardiovascular Prevention
- Esophageal and GI Pathology
- Tryptophan and brain disorders
- Health disparities and outcomes
- Pregnancy and preeclampsia studies
- Metabolism and Genetic Disorders
- Heart Failure Treatment and Management
- Cardiovascular Health and Risk Factors
- Diabetes Management and Education
- Cerebrovascular and Carotid Artery Diseases
- Atrial Fibrillation Management and Outcomes
University of Bergen
2015-2024
Norwegian Institute of Public Health
2013-2022
Norwegian Food Safety Authority
2015-2020
Massachusetts General Hospital
2020
Norwegian Medical Association
2019
Nasjonalforeningen for Folkehelsen
2019
Haukeland University Hospital
2001-2016
University of Oslo
1981-2016
Oslo University Hospital
2007-2016
Bevital (Norway)
2016
Air pollution has wide-ranging and deleterious effects on human health is a major issue for the global community. The Global Burden of Disease study described worldwide impact air with as many 3.1 million 52.8 all-cause all-age deaths being attributable to ambient in year 2010.1 Moreover, ranked ninth among modifiable disease risk factors, listed above other commonly recognized such low physical activity, high-sodium diet, high cholesterol, drug use. Finally, accounts 3.1%...
The purpose of the present study was to assess prevalence orthostatic hypotension and its associations with demographic characteristics, cardiovascular risk factors symptomatology, prevalent disease, selected clinical measurements in Cardiovascular Health Study, a multicenter, observational, longitudinal enrolling 5,201 men women aged 65 years older at initial examination. Blood pressure were obtained subjects supine position after they had been standing for 3 minutes. asymptomatic...
The aim was to study the prognostic value of plasma ceramides (Cer) as cardiovascular death (CV death) markers in three independent coronary artery disease (CAD) cohorts.Corogene is a prospective Finnish cohort including stable CAD patients (n = 160). Multiple lipid biomarkers and C-reactive protein were measured addition Cer(d18:1/16:0), Cer(d18:1/18:0), Cer(d18:1/24:0), Cer(d18:1/24:1). Subsequently, association between high-risk CV mortality investigated Special Program University...
Abstract Aims The aim of this study was to derive and validate the SCORE2-Older Persons (SCORE2-OP) risk model estimate 5- 10-year cardiovascular disease (CVD) in individuals aged over 70 years four geographical regions. Methods results Sex-specific competing risk-adjusted models for estimating CVD (CVD mortality, myocardial infarction, or stroke) were derived 65 without pre-existing atherosclerotic from Cohort Norway (28 503 individuals, 10 089 events). Models included age, smoking status,...
Recent evidence suggests a role for diet quality in the common mental disorders depression and anxiety. We aimed to investigate association between quality, dietary patterns, Norwegian adults.This cross-sectional study included 5731 population-based men women aged 46 49 70 74 years. Habitual was assessed using validated food frequency questionnaire, health measured Hospital Anxiety Depression Scale.After adjustments variables including age, education, income, physical activity, smoking,...
Abstract Aims Distinct ceramide lipids have been shown to predict the risk for cardiovascular disease (CVD) events, especially death. As phospholipids also linked with CVD risk, we investigated whether combination of ceramides phosphatidylcholines (PCs) would be synergistic in prediction events patients atherosclerotic coronary heart three independent cohort studies. Methods and results Ceramides PCs were analysed using liquid chromatography–mass spectrometry (LC-MS) studies: WECAC (The...
<h3>Background</h3> An association between depression and folate status has been demonstrated in clinical studies, whereas data are sparse on the relationship other components of 1-carbon metabolism such as vitamin B<sub>12</sub>, homocysteine, methylenetetrahydrofolate reductase<i>677C→T</i>polymorphism. The anxiety these is less well known. This study examined associations folate, total reductase<i>677C→T</i>polymorphism, a large population-based study. <h3>Methods</h3> Anxiety depression,...
The primary aim of the present study was to determine relation between measures subclinical cardiovascular disease and incidence clinical among 5201 adults 65 years age or older who were participating in Cardiovascular Health Study.A new method classifying at baseline examination Study included ankle-brachial blood pressure, carotid artery stenosis wall thickness, ECG echocardiographic abnormalities, positive response Rose Angina Claudication Questionnaire. Participants followed for an...
<h3>Objectives</h3> To examine tracking of body mass index (BMI) (weight in kilograms divided by the square height meters) from age 15 to 33 years, effect adolescent and adult health-related behavior parents' BMI education on BMI; changes lifestyle factors as predictors overweight obesity. <h3>Methods</h3> A longitudinal study with 18 20 years follow-up a cohort Oslo, Norway (N = 485); mean was at baseline. Weight, height, physical fitness, leisure time activity (LTPA), smoking, were...
To compare mortality rates for individuals with diabetes and without a history of foot ulcer (HFU) that the nondiabetic population.This population-based study included 155 diabetic an HFU, 1,339 63,632 who were all followed 10 years as end point.During follow-up period, total 49.0% HFU died, compared 35.2% 10.5% those diabetes. In Cox regression analyses adjusted age, sex, education, current smoking, waist circumference, having was associated more than twofold (2.29 [95% CI 1.82-2.88])...
To test the strain/iso-strain, interaction and buffer hypotheses of Job Demand-Control-Support model in relation to anxiety depression.Five thousand five hundred sixty-two workers with valid Questionnaire (DCSQ) scores were examined sub-scales Hospital Anxiety Depression Scale as outcomes. Multiple statistical methods applied.The strain iso-strain confirmed. Generally, additive non-interaction effects found between psychological demands, control social support. The refuted. Results from...
How did the study come about?A number of large population-based cardiovascular surveys have been conducted in Norway since beginning 1970s.The were carried out by National Health Screening Service cooperation with universities and local health authorities.All comprised a common set questions, standardized anthropometric blood pressure measurements non-fasting samples that analysed for serum lipids at Ulleva ˚l Hospital Laboratory.These provided considerable experience conducting large-scale...
<h3>Background:</h3> Active cigarette smoking has been established as a potent risk factor for carotid atherosclerosis in clinical populations; however, neither the role of active general populations nor impact environmental tobacco smoke well described. <h3>Methods:</h3> The association between artery wall thickness and was studied 12 953 black white men women, aged 45 to 65 years, examined Atherosclerosis Risk Communities Study. Participants were classified current smokers (n=3525), past...
Background Evidence that dietary antioxidants may prevent atherosclerotic disease is growing. The relationship between the intake of and supplemental vitamin C, α-tocopherol, provitamin A carotenoids average carotid artery wall thickness was studied in 6318 female 4989 male participants 45 to 64 years old Atherosclerosis Risk Communities Study. Methods Results Intake assessed by use a 66-item semiquantitative food-frequency questionnaire. Carotid intima-media measured as an indicator...
AimsEstimation of cardiovascular disease risk, using SCORE (Systematic COronary Risk Evaluation) is recommended by European guidelines on prevention. estimation inaccurate in older people. We hypothesized that this may be due to the assumption, inherent current risk systems, factors function similarly all age groups. aimed derive and validate a function, O.P., solely from data individuals aged 65 years older.
Abstract Homocysteine and related factors were evaluated as risk for subsequent hip fractures among 4766 elderly men women. High levels of homocysteine low folate predicted fracture, whereas vitamin B12 genotypes not to fracture risk. may be a modifiable factor fracture. Introduction: Elevated plasma total (tHcy) deficiencies are associated with osteoporosis We examined whether tHcy, folate, the methylenetetrahydrofolate reductase (MTHFR) 677C→T 1298C→T polymorphisms Materials Methods: This...