Massimo Franchini

ORCID: 0000-0002-8795-0580
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About
Contact & Profiles
Research Areas
  • Hemophilia Treatment and Research
  • Platelet Disorders and Treatments
  • Blood Coagulation and Thrombosis Mechanisms
  • Blood groups and transfusion
  • Venous Thromboembolism Diagnosis and Management
  • COVID-19 Clinical Research Studies
  • SARS-CoV-2 and COVID-19 Research
  • Coagulation, Bradykinin, Polyphosphates, and Angioedema
  • Hemostasis and retained surgical items
  • Hemoglobinopathies and Related Disorders
  • Blood transfusion and management
  • Atrial Fibrillation Management and Outcomes
  • Iron Metabolism and Disorders
  • Antiplatelet Therapy and Cardiovascular Diseases
  • Heparin-Induced Thrombocytopenia and Thrombosis
  • COVID-19 Impact on Reproduction
  • Trauma, Hemostasis, Coagulopathy, Resuscitation
  • Long-Term Effects of COVID-19
  • Blood donation and transfusion practices
  • Erythrocyte Function and Pathophysiology
  • Chronic Myeloid Leukemia Treatments
  • Myeloproliferative Neoplasms: Diagnosis and Treatment
  • Blood properties and coagulation
  • Air Quality and Health Impacts
  • Blood disorders and treatments

Azienda Ospedaliera Carlo Poma
2016-2025

Fondazione IRCCS Ca' Granda Ospedale Maggiore Policlinico
2013-2018

University of Verona
2002-2018

University of Milan
2018

GTx (United States)
2006-2017

Westmead Hospital
2011-2015

Faculty of 1000 (United States)
2015

University of Insubria
2013

Ospedale Maggiore
2013

University of Parma
2008-2012

Air pollution has wide-ranging and deleterious effects on human health is a major issue for the global community. The Global Burden of Disease study described worldwide impact air with as many 3.1 million 52.8 all-cause all-age deaths being attributable to ambient in year 2010.1 Moreover, ranked ninth among modifiable disease risk factors, listed above other commonly recognized such low physical activity, high-sodium diet, high cholesterol, drug use. Finally, accounts 3.1%...

10.1093/eurheartj/ehu458 article EN European Heart Journal 2014-12-09

Hyperimmune plasma from Covid-19 convalescent is a potential treatment for severe Covid-19. We conducted multicenter one arm proof of concept interventional study. Patients with disease moderate-to-severe Acute Respiratory Distress Syndrome, elevated C-reactive Protein and need mechanical ventilation and/or CPAP were enrolled. One to three 250-300 ml unit hyperimmune (neutralizing antibodies titer ≥1:160) administered. Primary outcome was 7-days hospital mortality. Secondary outcomes...

10.3324/haematol.2020.261784 article EN cc-by-nc Haematologica 2020-07-23

Within 6 months of infection with the Petaluma isolate feline immunodeficiency virus, specific-pathogen-free domestic cats exhibited a decrease in percentage and number circulating CD4+ lymphocytes CD4+/CD8+ T-cell ratio, along marginally significant depression pokeweed mitogen-induced lymphocyte proliferation vitro. There was no loss responsiveness to concanavalin A during this stage, were capable mounting satisfactory antibody response T-dependent, synthetic polypeptide immunogen. The...

10.1128/jvi.65.5.2225-2230.1991 article EN Journal of Virology 1991-05-01

It is unknown whether chronic kidney disease (CKD) associated with nonalcoholic fatty liver among patients type 2 diabetes. We followed 1760 outpatients diabetes and normal or near-normal function without overt proteinuria for 6.5 yr the occurrence of CKD (defined as and/or estimated GFR <60 ml/min per 1.73 m(2)). During follow-up, 547 participants developed incident CKD. Nonalcoholic disease, diagnosed by ultrasound exclusion other common causes was a moderately increased risk (hazard ratio...

10.1681/asn.2007101155 article EN Journal of the American Society of Nephrology 2008-04-03

Although a number of studies have demonstrated the influence ABO blood group on plasma levels von Willebrand factor (VWF), nature this association and its clinical importance is still largely unknown. In review, most recent advances in our understanding mechanisms by which determines VWF their impact will be discussed.

10.1186/1477-9560-5-14 article EN cc-by Thrombosis Journal 2007-01-01
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