A5043966926- Cancer Risks and Factors
- Global Cancer Incidence and Screening
- Cancer survivorship and care
- Nutritional Studies and Diet
- BRCA gene mutations in cancer
- Cardiovascular Health and Risk Factors
- Metabolism, Diabetes, and Cancer
- Nutrition and Health in Aging
- Nutrition, Genetics, and Disease
- Chemotherapy-induced cardiotoxicity and mitigation
- Family Support in Illness
- Estrogen and related hormone effects
- Breast Cancer Treatment Studies
- Cancer, Stress, Anesthesia, and Immune Response
- Colorectal Cancer Screening and Detection
- Alcohol Consumption and Health Effects
- Childhood Cancer Survivors' Quality of Life
- Multiple and Secondary Primary Cancers
- Economic and Financial Impacts of Cancer
- Palliative Care and End-of-Life Issues
- Adipose Tissue and Metabolism
- Physical Activity and Health
- Cancer-related cognitive impairment studies
- Epigenetics and DNA Methylation
- Diet and metabolism studies
Johns Hopkins University
2016-2025
Sidney Kimmel Cancer Center
2020-2025
Bloomberg (United States)
2023-2025
Sidney Kimmel Comprehensive Cancer Center
2015-2024
WellSpan Health
2024
University of Wisconsin Health
2024
University of Wisconsin–Madison
2024
Johns Hopkins Medicine
2020-2023
Harvard University
2023
University of Baltimore
2017-2022
The association between increasing body mass index (BMI; calculated as weight in kilograms divided by height meters squared) and risk of breast cancer is unique epidemiology that a crossover effect exists, with reduction before increase after menopause. inverse premenopausal poorly characterized but might be important the understanding causation.
There is growing evidence that breast cancer survivors have higher cardiovascular disease (CVD) mortality relative to the general population. Information on temporal patterns for all-cause and CVD among cancer-free women limited.All-cause CVD-related were compared in 628 with 3140 age-matched within CLUE II, a prospective cohort. We calculated adjusted hazard ratios (HRs) 95% confidence intervals (CIs) using Cox proportional hazards regression mortality, Fine Gray models account competing...
Abstract Background Excess body weight is an established cause of postmenopausal breast cancer, but it unknown if loss reduces risk. Methods Associations between change and risk cancer were examined among women aged 50 years older in the Pooling Project Prospective Studies Diet Cancer. In 10 cohorts, assessed on three surveys was used to examine patterns over approximately (interval 1 median = 5.2 years; interval 2 4.0 years). Sustained defined as no less than kg lost that not regained 2....
Abstract Associations between anthropometric factors and breast cancer (BC) risk have varied inconsistently by estrogen and/or progesterone receptor (ER/PR) status. prediagnostic of premenopausal postmenopausal BC overall ER/PR status subtypes were investigated in a pooled analysis 20 prospective cohorts, including 36,297 cases among 1,061,915 women, using multivariable Cox regression analyses, controlling for reproductive factors, diet other factors. We estimated dose–response relationships...
BACKGROUND Women who have coexisting comorbidities at the time of breast cancer diagnosis an increased risk and overall mortality. However, associations between newly diagnosed cardiovascular disease (CVD) mortality among these patients not been examined. METHODS The authors compared CVD, type 2 diabetes, hypertension CVD with identified in Missouri Cancer Registry. In total, 33,099 women had incident invasive inpatient outpatient hospital discharge data within years after were included:...
Background With the increasing number of cancer survivors in US, survivorship care plans (SCP) have been promoted to improve outcomes for patients. Few studies assessed if receipt SCPs differs by race/ethnicity. This study evaluated racial/ethnic disparities exist SCP among female living Maryland. Methods Survey data were analyzed 1,353 non-Hispanic white (NHW) and 280 Black (NHB) women with a self-reported history Maryland who completed Behavioral Risk Factor Surveillance (BRFSS) between...
Obesity is reported to be associated with poorer survival in women breast cancer, regardless of menopausal status. Our purpose was determine if the associations obesity cancer-specific, all-cause, and non-breast cancer mortality differ between Hispanic non-Hispanic white (NHW) cancer. Data on lifestyle medical history were collected for incident primary cases (298 NHW, 279 Hispanic) New Mexico Women's Health Study. Mortality ascertained through National Death Index Tumor Registry over 13...
Early-adulthood body size is strongly inversely associated with risk of premenopausal breast cancer. It unclear whether subsequent changes in weight affect risk. We pooled individual-level data from 17 prospective studies to investigate the association change cancer risk, considering strata initial weight, timing change, other factors and subtype. Hazard ratios (HR) 95% confidence intervals (CI) were obtained using Cox regression. Among 628,463 women, 10,886 diagnosed before menopause....
Chronic inflammation is suggested to be associated with specific cancer sites, including breast cancer. Recent research has focused on the roles of genes involved in leukotriene/lipoxygenase and prostaglandin/cyclooxygenase pathways etiology. We hypothesized that ALOX / COX CRP polymorphisms would risk mortality our sample Hispanic/Native American (NA) (1430 cases, 1599 controls) non‐Hispanic white (NHW) (2093 2610 women. A total 104 Ancestral Informative Markers was used distinguish...
Purpose Our objective is to pilot an advertisement-driven sampling procedure among African American (AA) breast cancer survivors living in Maryland. These study methods will inform a future population-based of AA at high risk poor outcomes due biological differences and social inequities. Methods This cross-sectional utilizes innovative, media-based advertisement campaign with associated media page recruit 100 survivors. Participants are biologically female, aged 18 older, identify as...
Background The incidence rate of breast cancer has been increasing over time across race/ethnicity in the United States. It is unclear whether these trends differ among stage, poverty, and geography subgroups. Methods Using data from North American Association Central Cancer Registries, this study estimated age‐adjusted rates women aged 50 to 84 years 1999 2017 by (non‐Hispanic Black, non‐Hispanic White, Hispanic) subgroups (stage, county‐level county urban/rural status, geographic region...
Background Although racial disparities in breast cancer (BC) mortality have been well documented the United States, little is known about impact of coexisting cardiovascular disease (CVD) and other clinical factors on Black‐White survival after diagnosis BC. This study examined associations race, CVD, at with hazard BC CVD‐related among patients identified from Maryland Cancer Registry. Methods A total 36,088 women (25,181 Whites 10,907 Blacks) diagnosed incident invasive between 2007 2017...
OBJECTIVE: We use the person-centered Pathway to Treatment framework assess scope of evidence on disparities in endometrial cancer stage at diagnosis. This report is intended facilitate interventions, research, and advocacy that reduce disparities. DATA SOURCES: completed a structured search electronic databases: PubMed, EMBASE, Scopus, ClinicalTrials.gov, Cochrane Central Register Controlled Trials databases. Included studies were published between January 2000 2023 addressed marginalized...
Our objective was to determine the association between racialized economic segregation and hazard of breast cancer mortality in Maryland.
Abstract Background Health advances due to developments in genomic medicine are unequally experienced the USA; racial differences uptake of genetic testing one factor this disparity. In collaboration with Black patients and diverse health care providers, we developing a patient-centered video intervention increase cancer among eligible Americans. The objective pilot work is explore acceptability support for key content components. Methods order create prototype, conducted targeted, secondary...
Few epidemiological studies have included Hispanics with the evaluation of effects cigarette smoking and breast cancer. We examined relationship between smoking, ethnicity, cancer risk using data from Breast Cancer Health Disparities Study (BCHDS).The BCHDS is a consortium three population-based case-control studies, including U.S. non-Hispanic whites (NHWs) (1,525 cases; 1,593 controls), Hispanics/Native Americans (1,265 1,495 Mexican women (990 1,049 controls). Multivariable logistic...
Abstract Physical activity is recommended for most cancer patients as a nonpharmacological therapy to improve prognosis. Few studies have investigated the association between physical and breast prognosis by ethnicity, biological, modifiable risk factors mortality. We long-term survival among survivors. A total of 397 survivors (96 Hispanic 301 non-Hispanic White (NHW)) from New Mexico HEAL study contributed baseline biological data approximately 6 months after diagnosis. Study outcomes...