A5015099801- Probiotics and Fermented Foods
- Gut microbiota and health
- Biosensors and Analytical Detection
- Microbial Metabolites in Food Biotechnology
- Advanced biosensing and bioanalysis techniques
- Salmonella and Campylobacter epidemiology
- Listeria monocytogenes in Food Safety
- Infant Nutrition and Health
- Autism Spectrum Disorder Research
- Microbial Metabolism and Applications
- Enterobacteriaceae and Cronobacter Research
- Bacteriophages and microbial interactions
- Nanoparticles: synthesis and applications
- Identification and Quantification in Food
- Clostridium difficile and Clostridium perfringens research
- Protein Hydrolysis and Bioactive Peptides
- Advanced Biosensing Techniques and Applications
- Fungal Biology and Applications
- Bacillus and Francisella bacterial research
- Helicobacter pylori-related gastroenterology studies
- Microbial Inactivation Methods
- Mycotoxins in Agriculture and Food
- Meat and Animal Product Quality
- Biochemical Analysis and Sensing Techniques
- Pharmacological Effects and Assays
Chongqing Medical University
2008-2025
Children's Hospital of Chongqing Medical University
2008-2025
Chengdu Second People's Hospital
2025
Northern Jiangsu People's Hospital
2024-2025
Air Force Medical University
2025
State Key Laboratory of Food Science and Technology
2015-2024
Nanchang University
2015-2024
University of Jinan
2022-2024
Ningbo College of Health Sciences
2019-2024
Southeast University
2003-2024
Humans have evolved intimate symbiotic relationships with a consortium of gut microbes (microbiome) and individual variations in the microbiome influence host health, may be implicated disease etiology, affect drug metabolism, toxicity, efficacy. However, molecular basis these microbe-host interactions roles bacterial species are obscure. We now demonstrate a"transgenomic" approach to link metabolic phenotype (metabotype) variation. used combination spectroscopic, microbiomic, multivariate...
Nanoparticles (NPs) size, surface functionalization, and concentration were claimed to contribute distribution toxicity outcomes of NPs in vivo. However, intrinsic chemical compositions caused inconsistent biodistribution toxic profiles which attracted little attention. In this study, silver nanoparticles (AgNPs) gold (AuNPs) used determine the biodistribution, toxickinetic, genotoxicity variances murine animals. The results demonstrated AgNPs AuNPs primarily deposited mononuclear phagocyte...
More and more evidences indicate that diseases of the central nervous system have been seriously affected by fecal microbes. However, little work is done to explore interaction between amyotrophic lateral sclerosis (ALS) In present study, high-throughput sequencing method was used compare intestinal microbial diversity healthy people ALS patients. The principal coordinate analysis, Venn unweighted pair-group using arithmetic averages (UPGMA) showed an obvious changes (group H) patients A),...
Exopolysaccharide (EPS) was extracted and purified from Lactobacillus plantarum WLPL04, which has been confirmed previously as a potential probiotic for its antagonistic immune-modulating activity. It molecular weight of 6.61 × 104 Da, consisting xylose, glucose, galactose in an approximate molar ratio 3.4:1.8:1. Microstructural studies demonstrated that the EPS appeared smooth sheet structure with many homogeneous rod-shaped lumps. The preliminary vitro assays indicated could significantly...
In spite of the immense benefits from iron oxide magnetic nanoparticles (IOMNs), there is scanty information regarding their metabolic activities and toxicity <italic>in vivo</italic>.
<italic>L. plantarum</italic>ZDY04 reduced choline-induced TMAO levels by remodeling the intestinal flora compositions and development of TMAO-induced atherosclerosis.
A Ru(phen)3(2+)-doped silica fluorescent nanoparticle (FN)-based immunochromatographic test strip (ICTS) sensor was developed for rapid, high sensitivity, easy to use, and low cost quantitative detection of enrofloxacin (ENR) residues in chicken meat. The fluorescence signal intensity the FNs at line (FI(T)) control (FI(C)) determined with a prototype portable reader. Unique properties Ru(phen)3(2+) doped nanoparticles (e.g., large Stokes shift, emission quantum yield, long lifetime) were...
Ulcerative colitis (UC) is an inflammatory bowel disease that difficult to cure, with rising incidence in recent decades. Probiotics have become a new strategy for UC treatment. In this study, we chose 2 multisource probiotics, Lactobacillus plantarum ZDY2013 from acid beans and Bifidobacterium bifidum WBIN03 infant feces, mixture of both, investigate the anti-inflammatory antioxidant effect on H2O2-induced oxidative damage HT-29 cell model dextran sodium sulfate (DSS)-induced mice. Compared...
Alpha-lipoic acid (α-LA) was evaluated in this study for its molecular mechanisms against liver oxidative damage and inflammatory responses induced by aflatoxin B1 (AFB1). Birds were randomly allocated into four groups with different diets three weeks: a basal diet, 300 mg/kg α-LA supplementation diet containing 74 μg/kg AFB1, AFB1. In the AFB1 group, expression of GSH-PX mRNA down-regulated (p < 0.05), levels lipid peroxide nitric oxide increased 0.05) chicken livers compared to those...
Sepsis leads to severe acute lung injury/acute respiratory distress syndrome (ALI/ARDS) that is associated with enhanced endoplasmic reticulum (ER) stress. Heme oxygenase-1 (HO-1), an ER-anchored protein, exerts antioxidant and protective functions under ALI. However, the role of HO-1 activation in development stress during sepsis remains unknown.Cecal ligation puncture (CLP) model was created induce septic Lung tissue ER measured 18 hours after CLP. The effects on ALI were investigated vivo...
ABSTRACT Streptococcus pneumoniae and a number of commensal streptococcal species are competent for natural genetic transformation. The habitat these bacteria is multispecies biofilms in the human oral cavity nasopharynx. Studies investigating lateral transfer virulence antibiotic resistance determinants among streptococci have shown that interspecies as well intraspecies gene exchange takes place environments. We previously action competence-specific murein hydrolase termed CbpD strongly...