Wanqing Wen
A5086118402- Genetic Associations and Epidemiology
- Genetic factors in colorectal cancer
- BRCA gene mutations in cancer
- Cancer, Lipids, and Metabolism
- Estrogen and related hormone effects
- Nutrition, Genetics, and Disease
- Cancer Risks and Factors
- Cancer Genomics and Diagnostics
- Nutritional Studies and Diet
- Epigenetics and DNA Methylation
- RNA modifications and cancer
- Colorectal Cancer Screening and Detection
- Molecular Biology Techniques and Applications
- Obesity, Physical Activity, Diet
- Lipoproteins and Cardiovascular Health
- Global Cancer Incidence and Screening
- Glutathione Transferases and Polymorphisms
- Cancer-related molecular mechanisms research
- Gene expression and cancer classification
- Metabolism, Diabetes, and Cancer
- Phytoestrogen effects and research
- Carcinogens and Genotoxicity Assessment
- Ferroptosis and cancer prognosis
- Inflammatory mediators and NSAID effects
- Bioinformatics and Genomic Networks
Vanderbilt University Medical Center
2015-2025
VA Tennessee Valley Healthcare System
2011-2025
Geriatric Research Education and Clinical Center
2004-2025
Jiangxi University of Traditional Chinese Medicine
2025
Vanderbilt University
2015-2024
The University of Western Australia
2024
Vanderbilt-Ingram Cancer Center
2004-2023
Roche (United States)
2023
University of Pittsburgh
2023
Southwest University
2023
Although cancer is a major cause of morbidity and mortality in most nations, the spectrum occurrence varies substantially worldwide. Most previous epidemiologic studies investigating etiology were conducted North American western European countries that are relatively homogenous terms spectrums many lifestyle exposures. These limitations may have hindered these from evaluating some important etiologic hypotheses. From 1996 to 2000, Shanghai Women's Health Study recruited 74,942 adult Chinese...
Substantial progress has been made in cancer diagnosis and treatment, resulting a steady improvement survival. The degree of by age, race, sex remains unclear.To quantify the survival over time United States.Longitudinal analyses follow-up data from 1990 to 2010, 1.02 million patients who had diagnosed as having colon or rectum, breast, prostate, lung, liver, pancreas, ovary 2009 were included 1 9 population-based registries National Cancer Institute Surveillance, Epidemiology, End Results...
The incidence of breast cancer among women in Shanghai, a traditionally low-risk population, has increased substantially over the past 20 years. To evaluate association menstrual and reproductive factors with risk influence these on temporal trend incidence, we analyzed data from Shanghai Breast Cancer Study, population-based case-control study recently completed Chinese urban Shanghai. In-person interviews were for 1,459 newly diagnosed between ages 25 64 1,556 controls frequency-matched to...
Although more than 20 genetic susceptibility loci have been reported for type 2 diabetes (T2D), most variants small to moderate effects and account only a proportion of the heritability T2D, suggesting that majority inter-person variation in this disease remains be determined. We conducted multistage, genome-wide association study (GWAS) within Asian Consortium Diabetes search T2D markers. From 590,887 SNPs genotyped 1,019 cases 1,710 controls selected from Chinese women Shanghai, we top...
Genetic factors play an important role in the etiology of both sporadic and familial breast cancer. We aimed to discover novel genetic susceptibility loci for conducted a four-stage genome-wide association study (GWAS) 19,091 cases 20,606 controls East-Asian descent including Chinese, Korean, Japanese women. After analyzing 690,947 SNPs 2,918 2,324 controls, we evaluated 5,365 replication 3,972 3,852 controls. Ninety-four were further 5,203 5,138 finally top 22 investigated up 17,423...
FTO is the strongest known genetic susceptibility locus for obesity. Experimental studies in animals suggest potential roles of regulating food intake. The interactive relation among variants, dietary intake and body mass index (BMI) complex results from previous often small-scale humans are highly inconsistent. We performed large-scale analyses based on data 177 330 adults (154 439 Whites, 5776 African Americans 17 115 Asians) 40 to examine: (i) association between FTO-rs9939609 variant (or...