Heming Wang
- Genetic Associations and Epidemiology
- Genomics and Rare Diseases
- Obstructive Sleep Apnea Research
- Sleep and related disorders
- Obesity, Physical Activity, Diet
- Epigenetics and DNA Methylation
- Cancer Genomics and Diagnostics
- Pancreatic function and diabetes
- Diet, Metabolism, and Disease
- Congenital heart defects research
- CO2 Reduction Techniques and Catalysts
- Advanced Photocatalysis Techniques
- Advanced Materials and Mechanics
- ATP Synthase and ATPases Research
- Tracheal and airway disorders
- Birth, Development, and Health
- Pickering emulsions and particle stabilization
- Lipoproteins and Cardiovascular Health
- Micro and Nano Robotics
- Diabetes and associated disorders
- Acute Myeloid Leukemia Research
- Sleep and Work-Related Fatigue
- Kruppel-like factors research
- Genomic variations and chromosomal abnormalities
- Electrocatalysts for Energy Conversion
Circadian (United States)
2019-2025
Harvard University
2019-2025
Brigham and Women's Hospital
2019-2025
Hainan University
2025
Mass General Brigham
2021-2025
Guangxi Normal University
2024
University of Science and Technology of China
2024
Broad Institute
2021
Case Western Reserve University
2018
Abstract Microbot collectives can cooperate to accomplish complex tasks that are difficult for a single individual. However, various force-induced microbot maintained by weak magnetic, light, and electric fields still face challenges such as unstable connections, the need continuous external stimuli source, imprecise individual control. Here, we construct magnetic light-driven ant capable of reconfiguring multiple assembled architectures with robustness. This methodology utilizes flexible...
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Abstract Background Sleep-disordered breathing is a common disorder associated with significant morbidity. The genetic architecture of sleep-disordered remains poorly understood. Through the NHLBI Trans-Omics for Precision Medicine (TOPMed) program, we performed first whole-genome sequence analysis breathing. Methods study sample was comprised 7988 individuals diverse ancestry. Common-variant and pathway analyses included an additional 13,257 individuals. We examined five complementary...
We performed large-scale genome-wide gene-sleep interaction analyses of lipid levels to identify novel genetic variants underpinning the biomolecular pathways sleep-associated disturbances and suggest possible druggable targets. collected data from 55 cohorts with a combined sample size 732,564 participants (87% European ancestry) on traits (high-density lipoprotein [HDL-c] low-density [LDL-c] cholesterol triglycerides [TG]). Short (STST) long (LTST) total sleep time were defined by extreme...
Abstract Background Alcohol intake influences plasma lipid levels and such effects may be modulated by genetic variants. Objective We aimed to characterize the role of aggregated rare low-frequency variants in gene alcohol consumption interactions associated with fasting levels. Design In Cohorts for Heart Aging Research Genomic Epidemiology (CHARGE) consortium, triglycerides (TG), high- low-density lipoprotein cholesterol (HDL-c LDL-c) were measured 34,153 European Americans from five...