Ganesh Chauhan

ORCID: 0000-0002-8564-5021
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About
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Research Areas
  • Genetic Associations and Epidemiology
  • Cancer-related molecular mechanisms research
  • Epigenetics and DNA Methylation
  • Bioinformatics and Genomic Networks
  • Birth, Development, and Health
  • Nutrition, Genetics, and Disease
  • Genetics and Neurodevelopmental Disorders
  • Alzheimer's disease research and treatments
  • Adipokines, Inflammation, and Metabolic Diseases
  • Neurological Disease Mechanisms and Treatments
  • Diabetes and associated disorders
  • Cerebrovascular and genetic disorders
  • Blood Coagulation and Thrombosis Mechanisms
  • Folate and B Vitamins Research
  • Cardiovascular Disease and Adiposity
  • Dementia and Cognitive Impairment Research
  • Hormonal Regulation and Hypertension
  • Genomic variations and chromosomal abnormalities
  • RNA regulation and disease
  • Regulation of Appetite and Obesity
  • Cancer-related gene regulation
  • RNA modifications and cancer
  • Health, Environment, Cognitive Aging
  • Nuclear Receptors and Signaling
  • Diet, Metabolism, and Disease

Institute of Genomics and Integrative Biology
2010-2025

Council of Scientific and Industrial Research
2010-2025

Academy of Scientific and Innovative Research
2025

Rajendra Institute of Medical Sciences
2021-2024

University of Michigan
2023

Inserm
2014-2022

Université de Bordeaux
2014-2022

Bordeaux Population Health
2015-2022

North Eastern Indira Gandhi Regional Institute of Health and Medical Sciences
2021

Indian Institute of Science Bangalore
2017-2021

Claudia L. Satizábal Hieab H.H. Adams Derrek P. Hibar Charles C. White Maria J. Knol and 95 more Jason L. Stein Markus Scholz Muralidharan Sargurupremraj Neda Jahanshad Gennady V. Roshchupkin Albert V. Smith Joshua C. Bis Xueqiu Jian Michelle Luciano Edith Hofer Alexander Teumer Sven J. van der Lee Jingyun Yang Lisa R. Yanek Tom V. Lee Shuo Li Yanhui Hu Jia Yu Koh John D. Eicher Sylvane Desrivières Alejandro Arias Väsquez Ganesh Chauhan Lavinia Athanasiu Miguel E. Rentería Sung Eun Kim David Hoehn Nicola J. Armstrong Qiang Chen Avram J. Holmes Anouk den Braber Iwona Kłoszewska Micael Andersson Thomas Espeseth O. Grimm Lucija Abramovic Saud Alhusaini Yuri Milaneschi Martina Papmeyer Tomas Axelsson Stefan Ehrlich Roberto Roiz‐Santiáñez Bernd Kraemer Asta K. Håberg Hannah Jones G. Bruce Pike Dan J. Stein Allison Stevens Janita Bralten Meike W. Vernooij Tamara B. Harris Irina Filippi A. Veronica Witte Tulio Guadalupe Katharina Wittfeld Thomas H. Mosley James T. Becker Nhat Trung Doan Saskia P. Hagenaars Yasaman Saba Gabriel Cuéllar-Partida Najaf Amin Saima Hilal Kwangsik Nho Nazanin Mirza‐Schreiber Konstantinos Arfanakis Diane M. Becker David Ames Aaron L. Goldman Phil Hyu Lee Dorret I. Boomsma Simon Lovestone Sudheer Giddaluru Stéphanie Le Hellard Manuel Mattheisen Marc M. Bohlken Dalia Kasperavičiūtė Lianne Schmaal Stephen M. Lawrie Ingrid Agartz Esther Walton Diana Tordesillas‐Gutiérrez Gareth E. Davies Jean Shin Jonathan Ipser Louis Vinke Martine Hoogman Tianye Jia Ralph Burkhardt Marieke Klein Fabrice Crivello Deborah Janowitz Owen Carmichael Unn K. Haukvik Benjamin S. Aribisala Helena Schmidt

10.1038/s41588-019-0511-y article EN Nature Genetics 2019-10-21
Hieab H.H. Adams Derrek P. Hibar Vincent Chouraki Jason L. Stein Paul Nyquist and 95 more Miguel E. Rentería Stella Trompet Alejandro Arias Väsquez Sudha Seshadri Sylvane Desrivières Ashley Beecham Neda Jahanshad Katharina Wittfeld Sven J. van der Lee Lucija Abramovic Saud Alhusaini Najaf Amin Micael Andersson Konstantinos Arfanakis Benjamin S. Aribisala Nicola J. Armstrong Lavinia Athanasiu Tomas Axelsson Alexa S. Beiser Manon Bernard Joshua C. Bis Laura M. E. Blanken Susan H. Blanton Marc M. Bohlken Marco P. Boks Janita Bralten Adam M. Brickman Owen Carmichael M. Mallar Chakravarty Ganesh Chauhan Qiang Chen Christopher R. K. Ching Gabriel Cuéllar-Partida Anouk den Braber Nhat Trung Doan Stefan Ehrlich Irina Filippi Tian Ge Sudheer Giddaluru Aaron L. Goldman Rebecca F. Gottesman Corina U. Greven O. Grimm Michael Griswold Tulio Guadalupe Johanna Haß Unn K. Haukvik Saima Hilal Edith Hofer David Hoehn Avram J. Holmes Martine Hoogman Deborah Janowitz Tianye Jia Dalia Kasperavičiūtė Sung Eun Kim Marieke Klein Bernd Kraemer Phil H. Lee Jiemin Liao David C. Liewald Lorna M. Lopez Michelle Luciano Christine Macare André F. Marquand Mar Matarín Karen A. Mather Manuel Mattheisen Bernard Mazoyer David R. McKay Rebekah McWhirter Yuri Milaneschi Nazanin Mirza‐Schreiber Ryan L. Muetzel Susana Muñoz Maniega Kwangsik Nho Allison C. Nugent Loes M. Olde Loohuis Jaap Oosterlaan Martina Papmeyer Irene Pappa Lukas Pirpamer Sara Pudas Benno Pütz Kumar B. Rajan Adaikalavan Ramasamy Jennifer S. Richards Shannon L. Risacher Roberto Roiz‐Santiáñez Nanda Rommelse Emma J. Rose Natalie A. Royle Tatjana Rundek Philipp G. Sämann Claudia L. Satizábal

10.1038/nn.4398 article EN Nature Neuroscience 2016-10-03
Sara L. Pulit Patrick F. McArdle Quenna Wong Rainer Malik Katrina Gwinn and 95 more Sefanja Achterberg Ale Algra Philippe Amouyel Christopher D. Anderson Donna K. Arnett Ethem Murat Arsava John Attia Hakan Ay Traci M. Bartz Thomas W.K. Battey Oscar Benavente Steve Bevan Alessandro Biffi Joshua C. Bis Susan H. Blanton Giorgio B. Boncoraglio Robert D. Brown A I Burgess Caty Carrera Sherita N. Chapman Smith Daniel I. Chasman Ganesh Chauhan Wei‐Min Chen Yu‐Ching Cheng Michael Chong Lisa Cloonan John W. Cole Ioana Cotlarciuc Carlos Cruchaga Elisa Cuadrado‐Godia Tushar Dave Jesse Dawson Stéphanie Debette Hossein Delavaran Cameron Dell Martin Dichgans Kimberly F. Doheny Chuanhui Dong David Duggan Gunnar Engström Michele K. Evans Xavier Estivill Pallejà Jessica D. Faul Israel Fernández‐Cadenas Myriam Fornage Philippe M. Frossard Karen L. Furie Dale M. Gamble Christian Gieger Anne‐Katrin Giese Eva Giralt‐Steinhauer Hector M. González An Goris Sólveig Grétarsdóttir Raji P. Grewal Ulrike Grittner Stefan Gustafsson Buhm Han Graeme J. Hankey Laura Heitsch Peter Higgins Marc C. Hochberg Elizabeth G. Holliday Jemma C. Hopewell Richard B. Horenstein George Howard M. Arfan Ikram Andreea Ilinca Erik Ingelsson Marguerite R. Irvin Rebecca D. Jackson Christina Jern Jordi Jiménez Conde Julie A. Johnson Katarina Jood Muhammad S Kahn Robert C. Kaplan L. Jaap Kappelle Sharon L.R. Kardia Keith L. Keene Brett Kissela Dawn Kleindorfer Simon A. Koblar Daniel L. Labovitz Lenore J. Launer Cathy C. Laurie Cecelia Laurie Jin‐Moo Lee Jin‐Moo Lee Manuel Lehm Robin Lemmens Christopher Levi Didier Leys Cecilia M. Lindgren W. T. Longstreth

10.1016/s1474-4422(15)00338-5 article EN The Lancet Neurology 2015-12-19

OBJECTIVE Common variants in PPARG, KCNJ11, TCF7L2, SLC30A8, HHEX, CDKN2A, IGF2BP2, and CDKAL1 genes have been shown to be associated with type 2 diabetes European populations by genome-wide association studies. We studied the of common these eight related traits Indians combining data from two independent case–control RESEARCH DESIGN AND METHODS genotyped single nucleotide polymorphisms (PPARG-rs1801282, KCNJ11-rs5219, TCF7L2-rs7903146, SLC30A8-rs13266634, HHEX-rs1111875, CDKN2A-rs10811661,...

10.2337/db09-1386 article EN cc-by-nc-nd Diabetes 2010-04-27
Benjamin F.J. Verhaaren Stéphanie Debette Joshua C. Bis Jennifer A. Smith M. Kamran Ikram and 95 more Hieab H.H. Adams Ashley Beecham Kumar B. Rajan Lorna M. Lopez Sandra Barral Mark A. van Buchem Jeroen van der Grond Albert V. Smith Katrin Hegenscheid Neelum T. Aggarwal Mariza de Andrade Elizabeth J. Atkinson Marian Beekman Alexa S. Beiser Susan H. Blanton Eric Boerwinkle Adam M. Brickman R. Nick Bryan Ganesh Chauhan Christopher Chen Vincent Chouraki Anton J. M. de Craen Fabrice Crivello Ian J. Deary Joris Deelen Philip L. De Jager Carole Dufouil Mitchell S.V. Elkind Denis A. Evans Paul Freudenberger Rebecca F. Gottesman Vilmundur Guðnason Mohamad Habes Susan R. Heckbert Gerardo Heiss Saima Hilal Edith Hofer Albert Hofman Carla A. Ibrahim‐Verbaas David S. Knopman Cora E. Lewis Jiemin Liao David C. Liewald Michelle Luciano Aad van der Lugt Oliver Martinez Richard Mayeux Bernard Mazoyer Mike A. Nalls Matthias Nauck Wiro J. Niessen Ben A. Oostra Bruce M. Psaty Kenneth Rice Jerome I. Rotter Bettina von Sarnowski Helena Schmidt Pamela J. Schreiner Maaike Schuur Stephen Sidney Sigurður Sigurðsson P. Eline Slagboom David J.M. Stott John C. van Swieten Alexander Teumer Anna Maria Töglhofer Matthew Traylor Stella Trompet Stephen T. Turner Christophe Tzourio Hae‐Won Uh André G. Uitterlinden Meike W. Vernooij Jing Jing Wang Tien Yin Wong Joanna M. Wardlaw B. Gwen Windham Katharina Wittfeld Christiane Wolf Clinton B. Wright Qiong Yang Wei Zhao Alex Zijdenbos J. Wouter Jukema Ralph L. Sacco Sharon L. R. Kardia Philippe Amouyel Thomas H. Mosley W. T. Longstreth Charles DeCarli Cornelia M. van Duijn Reinhold Schmidt Lenore J. Launer Hans J. Grabe Sudha Seshadri

Background— The burden of cerebral white matter hyperintensities (WMH) is associated with an increased risk stroke, dementia, and death. WMH are highly heritable, but their genetic underpinnings incompletely characterized. To identify novel variants influencing burden, we conducted a meta-analysis multiethnic genome-wide association studies. Methods Results— We included 21 079 middle-aged to elderly individuals from 29 population-based cohorts, who were free dementia stroke European (n=17...

10.1161/circgenetics.114.000858 article EN Circulation Cardiovascular Genetics 2015-02-09
Louise V. Wain Ahmad Vaez Rick Jansen Roby Joehanes Peter J. van der Most and 95 more A. Mesut Erzurumluoglu Paul F. O’Reilly Claudia P. Cabrera Helen R. Warren Lynda M. Rose Germaine C. Verwoert Jouke‐Jan Hottenga Rona J. Strawbridge Tõnu Esko Dan E. Arking Shih-Jen Hwang Xiuqing Guo Zoltán Kutalik Stella Trompet Nick Shrine Alexander Teumer Janina S. Ried Joshua C. Bis Albert V. Smith Najaf Amin Ilja M. Nolte Leo‐Pekka Lyytikäinen Anubha Mahajan Nicholas J. Wareham Edith Hofer Peter K. Joshi Kati Kristiansson Michela Traglia Aki S. Havulinna Anuj Goel Mike A. Nalls Siim Sõber Dragana Vuckovic Jian’an Luan Fabiola Del Greco M Kristin L. Ayers Jaume Marrugat Daniela Ruggiero Lorna M. Lopez Teemu Niiranen Stefan Enroth Anne Jackson Christopher P. Nelson Jennifer E. Huffman Weihua Zhang Jonathan Marten Ilaria Gandin Sarah E. Harris Tatijana Zemunik Yingchang Lu Εvangelos Εvangelou Nabi Shah Martin H. de Borst Massimo Mangino Bram P. Prins Archie Campbell Ruifang Li‐Gao Ganesh Chauhan Christopher Oldmeadow Gonçalo Abecasis Maryam Abedi Caterina Barbieri Michael R. Barnes Chiara Batini John Beilby Tineka Blake Michael Boehnke Erwin P. Böttinger Peter S. Braund Morris J. Brown Marco Brumat Harry Campbell John C. Chambers Massimiliano Cocca Francis S. Collins John Connell Heather J. Cordell Jeffrey Damman Gail Davies Eco J. C. de Geus Renée de Mutsert Joris Deelen Yusuf Demirkale Alex S. F. Doney Marcus Dörr Martin Farrall Teresa Ferreira Mattias Frånberg He Gao Vilmantas Giedraitis Christian Gieger Franco Giulianini Alan J. Gow Anders Hamsten Tamara B. Harris

Elevated blood pressure is a major risk factor for cardiovascular disease and has substantial genetic contribution. Genetic variation influencing the potential to identify new pharmacological targets treatment of hypertension. To discover additional novel loci, we used 1000 Genomes Project–based imputation in 150 134 European ancestry individuals sought significant evidence independent replication further 228 245 individuals. We report 6 signals association or near HSPB7 , TNXB LRP12...

10.1161/hypertensionaha.117.09438 article EN Hypertension 2017-07-25
Yun Ju Sung Thomas W. Winkler Lisa de las Fuentes Amy R. Bentley Michael R. Brown and 95 more Aldi T. Kraja Karen Schwander Ιωάννα Ντάλλα Xiuqing Guo Nora Franceschini Yingchang Lu Ching‐Yu Cheng Xueling Sim Dina Vojinović Jonathan Marten Solomon K. Musani Changwei Li Mary F. Feitosa Tuomas O. Kilpeläinen Melissa A. Richard Raymond Noordam Stella Aslibekyan Hugues Aschard Traci M. Bartz Rajkumar Dorajoo Yongmei Liu Alisa K. Manning Tuomo Rankinen Albert V. Smith Salman M. Tajuddin Bamidele O. Tayo Helen R. Warren Wei Zhao Yanhua Zhou Nana Matoba Tamar Sofer Maris Alver Marzyeh Amini Mathilde Boissel Jin Fang Chai Xu Chen Jasmin Divers Ilaria Gandin Chuan Gao Franco Giulianini Anuj Goel Sarah E. Harris Fernando Pires Hartwig A.R.V.R. Horimoto Fang‐Chi Hsu Anne Jackson Mika Kähönen Anuradhani Kasturiratne Brigitte Kühnel Karin Leander Wen‐Jane Lee Keng‐Hung Lin Jian ’an Luan Colin A. McKenzie He Meian Christopher P. Nelson Rainer Rauramaa Nicole Schupf Robert A. Scott Wayne H.-H. Sheu Alena Stančáková Fumihiko Takeuchi Peter J. van der Most Tibor V. Varga Heming Wang Yajuan Wang Erin B. Ware Stefan Weiß Wanqing Wen Lisa R. Yanek Weihua Zhang Jing Hua Zhao Saima Afaq Tamuno Alfred Najaf Amin Dan E. Arking Tin Aung R. Graham Barr Lawrence F. Bielak Eric Boerwinkle Erwin P. Böttinger Peter S. Braund Jennifer A. Brody Ulrich Broeckel Claudia P. Cabrera Brian E. Cade Yu Caizheng A.M. Campbell Mickaël Canouil Aravinda Chakravarti Ganesh Chauhan Kaare Christensen Massimiliano Cocca Francis S. Collins John Connell

10.1016/j.ajhg.2018.01.015 article EN publisher-specific-oa The American Journal of Human Genetics 2018-02-15
Céline Bellenguez Camille Charbonnier Benjamin Grenier‐Boley Olivier Quenez Kilan Le Guennec and 84 more Gaël Nicolas Ganesh Chauhan David Wallon Stéphane Rousseau Anne Richard Anne Boland Guillaume Bourque Hans Markus Münter Robert Olaso Vincent Meyer Adeline Rollin‐Sillaire Florence Pasquier Luc Letenneur Richard Redon Jean‐François Dartigues Christophe Tzourio Thierry Frébourg Mark Lathrop Jean‐François Deleuze Didier Hannequin Emmanuelle Génin Philippe Amouyel Stéphanie Debette Jean‐Charles Lambert Dominique Campion Didier Hannequin Dominique Campion David Wallon Olivier Martinaud Aline Zaréa Gaël Nicolas Adeline Rollin‐Sillaire Stéphanie Bombois Marie-Anne Mackowiak Vincent Deramecourt Florence Pasquier Agnès Michon Isabelle Le Ber Bruno Dubois Olivier Godefroy Frédérique Etcharry‐Bouyx Valérie Chauviré Ludivine Chamard Eric Berger Éloi Magnin Jean‐François Dartigues Sophie Auriacombe François Tison Vincent de la Sayette Dominique Castan Elsa Dionet François Sellal Olivier Rouaud Christel Thauvin Olivier Moreaud Mathilde Sauvée Maïté Formaglio Hélène Mollion Isabelle Roullet‐Solignac Alain Vighetto Bernard Croisile Mira Didic Olivier Félician Lejla Koric Mathieu Ceccaldi Audrey Gabelle Cecilia Marelli Pierre Labauge Thérèse Jonveaux Martine Vercelletto Claire Boutoleau‐Bretonnière Giovanni Castelnovo Claire Paquet Julien Dumurgier Jacques Hugon Foucauld De Boisgueheneuc Serge Belliard Serge Bakchine Marie Sarazin Marie‐Odile Barrellon Bernard Laurent Frédéric Blanc Jérémie Pariente Snejana Jurici

10.1016/j.neurobiolaging.2017.07.001 article EN Neurobiology of Aging 2017-07-15

Objective Genome‐wide association studies (GWAS) have been successful at identifying associations with stroke and subtypes, but not yet identified any solely small vessel (SVS). SVS comprises one quarter of all ischemic is a major manifestation cerebral disease, the primary cause vascular cognitive impairment. Studies across neurological traits shown that younger‐onset cases an increased genetic burden. We leveraged this burden by performing age‐at‐onset informed GWAS meta‐analysis,...

10.1002/ana.24840 article EN cc-by Annals of Neurology 2016-12-20

The genetic contribution to dilated perivascular space (dPVS) burden-an emerging MRI marker of cerebral small vessel disease-is unknown. We measured the heritability dPVS burden and its shared with other markers disease.The study sample comprised 1597 participants from population-based Three City (3C) Dijon Study, brain genome-wide genotyping (mean age, 72.8±4.1 years; 61% women). lacunar infarcts were rated on a semiquantitative scale, whereas an automated algorithm generated white matter...

10.1161/strokeaha.117.019309 article EN Stroke 2018-01-08
Stéphanie Debette Carla A. Ibrahim Verbaas Jan Bressler Maaike Schuur Albert V. Smith and 95 more Joshua C. Bis Gail Davies Christiane Wolf Vilmundur Guðnason Lori B. Chibnik Qiong Yang Anita L. DeStefano Dominique J.‐F. de Quervain Velandai Srikanth Jari Lahti Hans J. Grabe Jennifer A. Smith Lutz Priebe Lei Yu Nazanin Karbalai Caroline Hayward James F. Wilson Harry Campbell Katja Petrovic Myriam Fornage Ganesh Chauhan Robin W. Yeo Ruth Boxall James T. Becker Oliver Stegle Karen A. Mather Vincent Chouraki Qi Sun Lynda M. Rose Susan M. Resnick Christopher Oldmeadow Mirna Kirin Alan F. Wright Marıá K. Jónsdóttir Rhoda Au Albert J. Becker Najaf Amin Mike A. Nalls Stephen T. Turner Sharon L. R. Kardia Ben A. Oostra Gwen Windham Laura H. Coker Wei Zhao David S. Knopman Gerardo Heiss Michael Griswold Rebecca F. Gottesman Véronique Vitart Nicholas D. Hastie Lina Zgaga Igor Rudan Ozren Polašek Elizabeth G. Holliday Peter R. Schofield Seung Hoan Choi Toshiko Tanaka Yang An Rodney T. Perry Richard Kennedy Michèle M. Sale Jing Wang Virginia G. Wadley David C. Liewald Paul M. Ridker Alan J. Gow Alison Pattie John M. Starr David J. Porteous Xuan Liu Russell Thomson Nicola J. Armstrong Gudny Eiriksdottir Arezoo Assareh Nicole A. Kochan Elisabeth Widén Aarno Palotie Yi‐Chen Hsieh Johan G. Eriksson Christian Vogler John C. van Swieten Joshua Shulman Alexa S. Beiser Jerome I. Rotter Carsten Oliver Schmidt Wolfgang Hoffmann Markus M. Nöthen Luigi Ferrucci John Attia André G. Uitterlinden Philippe Amouyel Jean‐François Dartigues Hélène Amieva Katri Räikkönen Melissa García

10.1016/j.biopsych.2014.08.027 article EN Biological Psychiatry 2014-11-25
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