Tien Yin Wong

ORCID: 0000-0002-8448-1264
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About
Contact & Profiles
Research Areas
  • Retinal Imaging and Analysis
  • Retinal Diseases and Treatments
  • Glaucoma and retinal disorders
  • Retinal and Optic Conditions
  • Ophthalmology and Visual Impairment Studies
  • Corneal surgery and disorders
  • Genetic Associations and Epidemiology
  • Blood Pressure and Hypertension Studies
  • Cardiovascular Health and Disease Prevention
  • Chronic Kidney Disease and Diabetes
  • Intraocular Surgery and Lenses
  • Ocular Diseases and Behçet’s Syndrome
  • Retinopathy of Prematurity Studies
  • Renal and Vascular Pathologies
  • Acute Ischemic Stroke Management
  • Diabetes, Cardiovascular Risks, and Lipoproteins
  • Ophthalmology and Visual Health Research
  • Birth, Development, and Health
  • Pregnancy and preeclampsia studies
  • Dialysis and Renal Disease Management
  • Digital Imaging for Blood Diseases
  • Dementia and Cognitive Impairment Research
  • Cerebral Venous Sinus Thrombosis
  • Cerebrovascular and Carotid Artery Diseases
  • Metabolomics and Mass Spectrometry Studies

National University of Singapore
2016-2025

Singapore National Eye Center
2016-2025

Singapore Eye Research Institute
2016-2025

Tsinghua University
2022-2025

Duke-NUS Medical School
2016-2025

Beijing Tsinghua Chang Gung Hospital
2023-2025

SingHealth
2014-2025

Tung Wah Hospital
2025

Tianjin Medical University
2025

Tianjin Medical University Eye Hospital
2025

<h3>Importance</h3> A deep learning system (DLS) is a machine technology with potential for screening diabetic retinopathy and related eye diseases. <h3>Objective</h3> To evaluate the performance of DLS in detecting referable retinopathy, vision-threatening possible glaucoma, age-related macular degeneration (AMD) community clinic-based multiethnic populations diabetes. <h3>Design, Setting, Participants</h3> Diagnostic diseases was evaluated using 494 661 retinal images. trained (using 76...

10.1001/jama.2017.18152 article EN JAMA 2017-12-12

The past decade has allowed the development of a multitude digital tools. Now they can be used to remediate COVID-19 outbreak.

10.1038/s41591-020-0824-5 article EN other-oa Nature Medicine 2020-03-27

AbstractBackground/Purpose. Recent findings suggest that an objective assessment of retinal vessel caliber from fundus photographs provide information about the association microvascular characteristics with macrovascular disease. Current methods used to quantify caliber, introduced by Parr and Hubbard, are not independent scale affected number vessels. To improve upon these we introduce revised formulas for quantifying caliber. Methods. Revised were estimated using measurements 44 young...

10.1076/ceyr.27.3.143.16049 article EN Current Eye Research 2003-01-01

OF microvascular and macrovascular processes to the risk of coronary heart disease (CHD) is unknown, but its elucidation important from etiological, preventive, therapeutic perspectives. 1,2Coronary may explain occurrence myocardial ischemia without overt artery blockage, [3][4][5][6][7] as well failure 8,9 mortality 9 after infarction (MI).Because women with chest pain are more likely have normal arteries, 1-4,7 higher rates an MI, 10,11 poorer outcomes bypass graft surgery, 12 it has been...

10.1001/jama.287.9.1153 article EN JAMA 2002-03-06

Background Mild retinopathy (microaneurysms or dot-blot hemorrhages) is observed in persons without diabetes hypertension and may reflect microvascular disease other organs. We conducted a genome-wide association study (GWAS) of mild diabetes. Methods A working group agreed on phenotype harmonization, covariate selection analytic plans for within-cohort GWAS. An inverse-variance weighted fixed effects meta-analysis was performed with GWAS results from six cohorts 19,411 Caucasians. The...

10.1371/journal.pone.0054232 article EN cc-by PLoS ONE 2013-02-05

Background— Diabetes mellitus increases the risk of cardiovascular disease (CVD) and all-cause mortality. The relationship between milder elevations blood glucose mortality is less clear. This study investigated whether impaired fasting tolerance, as well diabetes mellitus, increase CVD Methods Results— In 1999 to 2000, tolerance status was determined in 10 428 participants Australian Diabetes, Obesity, Lifestyle Study (AusDiab). After a median follow-up 5.2 years, 298 deaths occurred (88...

10.1161/circulationaha.106.685628 article EN Circulation 2007-06-19
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