А. П. Деревянко
A5010051113- Pleistocene-Era Hominins and Archaeology
- Archaeology and ancient environmental studies
- Forensic Anthropology and Bioarchaeology Studies
- Marine and environmental studies
- Forensic and Genetic Research
- Indigenous Studies and Ecology
- Geology and Paleoclimatology Research
- Ancient and Medieval Archaeology Studies
- Evolution and Paleontology Studies
- Image Processing and 3D Reconstruction
- Paleopathology and ancient diseases
- Pacific and Southeast Asian Studies
- Geological Studies and Exploration
- Rangeland Management and Livestock Ecology
- Yersinia bacterium, plague, ectoparasites research
- Animal Diversity and Health Studies
- Genetic diversity and population structure
- Soil and Environmental Studies
- Linguistics and Cultural Studies
- Archaeology and Rock Art Studies
- Geological and Geophysical Studies
- Geological and Geochemical Analysis
- Eurasian Exchange Networks
- European Politics and Security
- Race, Genetics, and Society
Institute of Archaeology and Ethnography
2016-2025
Altai State University
2015-2025
Russian Academy of Sciences
2012-2024
Institute of Archaeology
2010-2024
Google (United States)
2022
Siberian Branch of the Russian Academy of Sciences
2004-2021
Institute of Archeology and Ethnography
2017-2019
Novosibirsk State University
2015-2018
Institute of History
2002
We present a DNA library preparation method that has allowed us to reconstruct high-coverage (30×) genome sequence of Denisovan, an extinct relative Neandertals. The quality this allows direct estimation Denisovan heterozygosity indicating genetic diversity in these archaic hominins was extremely low. It also tentative dating the specimen on basis "missing evolution" its genome, detailed measurements and Neandertal admixture into present-day human populations, generation near-complete...
Using DNA extracted from a finger bone found in Denisova Cave southern Siberia, we have sequenced the genome of an archaic hominin to about 1.9-fold coverage. This individual is group that shares common origin with Neanderthals. population was not involved putative gene flow Neanderthals into Eurasians; however, data suggest it contributed 4–6% its genetic material genomes present-day Melanesians. We designate this 'Denisovans' and may been widespread Asia during Late Pleistocene epoch. A...
With the exception of Neanderthals, from which DNA sequences numerous individuals have now been determined, number and genetic relationships other hominin lineages are largely unknown. Here we report a complete mitochondrial (mt) sequence retrieved bone excavated in 2008 Denisova Cave Altai Mountains southern Siberia. It represents hitherto unknown type mtDNA that shares common ancestor with anatomically modern human Neanderthal mtDNAs about 1.0 million years ago. This indicates it derives...
Ancient human movements through Asia DNA has allowed us to begin tracing the history of across globe. Narasimhan et al. identify a complex pattern migrations and admixture events in South Central by performing genetic analysis more than 500 people who lived over past 8000 years (see Perspective Schaefer Shapiro). They establish key phases population prehistory Eurasia, including spread farming peoples from Near East, with both westward eastward. The known as Yamnaya Bronze Age also moved...
Significance Strict laboratory precautions against present day human DNA contamination are standard in ancient studies, but is already inside many fossils from previous handling without specific precautions. We designed a statistical framework to isolate endogenous sequences contaminating using postmortem degradation patterns and were able reduce high-contamination fractions negligible levels. captured contaminated Neandertal bone Okladnikov Cave Siberia used our method assemble its...
Although a rich record of Pleistocene human-associated archaeological assemblages exists, the scarcity hominin fossils often impedes understanding which hominins occupied site. Using targeted enrichment mitochondrial DNA, we show that cave sediments represent source ancient mammalian DNA includes traces even at sites and in layers where no remains have been discovered. By automation-assisted screening numerous sediment samples, detected Neandertal eight from four caves Eurasia. In Denisova...
Significance We use a hybridization approach to enrich the DNA from protein-coding fraction of genomes two Neandertal individuals Spain and Croatia. By analyzing these exomes together with genome sequence Siberia we show that genetic diversity Neandertals was lower than present-day humans pattern coding variation suggests populations were small isolated one another. also genes involved in skeletal morphology have changed more expected on evolutionary lineage whereas pigmentation behavior...
We sequenced the genome of a Neandertal from Chagyrskaya Cave in Altai Mountains, Russia, to 27-fold genomic coverage. show that this was female and she more related Neandertals western Eurasia [Prüfer et al., Science 358, 655–658 (2017); Hajdinjak Nature 555, 652–656 (2018)] than who lived earlier Denisova 505, 43–49 (2014)], which is located about 100 km away. About 12.9% spanned by homozygous regions are between 2.5 10 centiMorgans (cM) long. This consistent with fact Siberian relatively...
Significance Denisovans are a sister group of Neandertals that were identified on the basis nuclear genome sequence from bone Denisova Cave (Siberia). The only other Denisovan specimen described to date is molar same site. We present here DNA sequences this and morphological description, as well mitochondrial another Cave, thus extending number individuals known three. diversity among higher than Neandertals, but lower present-day humans. mtDNA one has accumulated fewer substitutions mtDNAs...
The value of dirty DNA Environmental can identify the presence species, even from distant past. Surveying three cave sites in western Europe and southern Siberia, Vernot et al. identified nuclear confirmed that it is close relatives anatomically modern humans—Neanderthal Denisovan individuals. A phylogenetic analysis modeling show sediment samples several layers corresponds to previously studied skeletal remains. These results demonstrate environmental data be applied study population...
Denisova Cave in southern Siberia is the type locality of Denisovans, an archaic hominin group who were related to Neanderthals1-4. The dozen remains recovered from deposits also include Neanderthals5,6 and child a Neanderthal Denisovan7, which suggests that was contact zone between these hominins. However, uncertainties persist about order groups appeared at site, timing environmental context occupation, association particular with archaeological assemblages5,8-11. Here we report analysis...
Abstract Genomic analyses of Neanderthals have previously provided insights into their population history and relationship to modern humans 1–8 , but the social organization Neanderthal communities remains poorly understood. Here we present genetic data for 13 from two Middle Palaeolithic sites in Altai Mountains southern Siberia: 11 Chagyrskaya Cave 9,10 2 Okladnikov —making this one largest studies a date. We used hybridization capture obtain genome-wide nuclear data, as well mitochondrial...
Abstract DNA sequencing has revolutionised our understanding of archaic humans during the Middle and Upper Palaeolithic. Unfortunately, while many Palaeolithic sites contain large numbers bones, majority these lack diagnostic features necessary for traditional morphological identification. As a result recovery Pleistocene-age human remains is extremely rare. To circumvent this problem we have applied method collagen fingerprinting to more than 2000 fragmented bones from site Denisova Cave,...
Y chromosome evolution in Neanderthals The genomes of archaic hominins have been sequenced and compared with that modern humans. However, most individuals high-quality sequences available female. Petr et al. performed targeted sequencing the paternally inherited chromosomes from three two Denisovans (see Perspective by Schierup). Comparisons diverse human indicated that, similar to maternally mitochondria, Neanderthal were more closely related each other Denisovan chromosome. This result...
DNA retrieved from a tooth discovered deep in Denisova Cave allows us to assign it the Denisovans, group of archaic hominins.
Significance Neanderthals once inhabited Europe and western Asia, spreading as far east the Altai Mountains in southern Siberia, but geographical origin time of arrival populations remain unresolved. Excavations at Chagyrskaya Cave foothills have yielded 90,000 stone artifacts, numerous bone tools, 74 Neanderthal fossils, animal plant remains recovered from 59,000- to 49,000-year-old deposits. The made distinctive tools that closely resemble Micoquian artifacts eastern Europe, whereas other...
Significance DNA preserved in sediments has emerged as an important source of information about past ecosystems, independent the discovery skeletal remains. However, little is known sources sediment DNA, factors affecting its long-term preservation, and extent to which it may be translocated after deposition. Here, we show that impregnated blocks intact are excellent archives DNA. distribution highly heterogeneous at microscale cave studied, suggesting postdepositional movement unlikely a...