Aleksandr Khokhlov
A5066472175- Forensic and Genetic Research
- Forensic Anthropology and Bioarchaeology Studies
- Archaeology and ancient environmental studies
- Ancient and Medieval Archaeology Studies
- Genetic diversity and population structure
- Marine and environmental studies
- Paleopathology and ancient diseases
- Yersinia bacterium, plague, ectoparasites research
- Race, Genetics, and Society
- HIV Research and Treatment
- Cultural, Linguistic, Economic Studies
- Hepatitis B Virus Studies
- Historical and Archaeological Studies
- Folklore, Mythology, and Literature Studies
- Engineering and Environmental Studies
- Dental Trauma and Treatments
- Educational Methods and Teacher Development
- Salmonella and Campylobacter epidemiology
- Genetic and phenotypic traits in livestock
- dental development and anomalies
- Bacillus and Francisella bacterial research
- Psycholinguistics and Behavioral Studies
- Rabies epidemiology and control
- vaccines and immunoinformatics approaches
- Physical Education and Training Studies
Samara State University of Social Sciences and Education
2016-2025
Institute of Anthropology and Ethnography
2016-2024
Russian Academy of Sciences
2016-2024
Kazan Federal University
2023-2024
Romanian Academy
2023
University of Bucharest
2023
Pennsylvania State University
2023
Institute of Archaeology
2018
Samara State Technical University
2016
National Research Tomsk State University
2016
Ancient human movements through Asia DNA has allowed us to begin tracing the history of across globe. Narasimhan et al. identify a complex pattern migrations and admixture events in South Central by performing genetic analysis more than 500 people who lived over past 8000 years (see Perspective Schaefer Shapiro). They establish key phases population prehistory Eurasia, including spread farming peoples from Near East, with both westward eastward. The known as Yamnaya Bronze Age also moved...
Abstract The origin of Yersinia pestis and the early stages its evolution are fundamental subjects investigation given high virulence mortality that resulted from past pandemics. Although earliest evidence Y. infections in humans has been identified Late Neolithic/Bronze Age Eurasia (LNBA 5000–3500y BP), these strains lack key genetic components required for flea adaptation, thus making their mode transmission disease presentation unclear. Here, we reconstruct ancient genomes individuals...
Abstract During the 1 st millennium before Common Era (BCE), nomadic tribes associated with Iron Age Scythian culture spread over Eurasian Steppe, covering a territory of more than 3,500 km in breadth. To understand demographic processes behind culture, we analysed genomic data from eight individuals and mitochondrial dataset 96 originating eastern western parts Steppe. Genomic inference reveals that Scythians east west steppe zone can best be described as mixture Yamnaya-related ancestry an...
Ancient DNA traces the history of hepatitis B Hepatitis virus (HBV) infections represent a worldwide human health concern. To study this pathogen, Kocher et al . identified 137 remains with detectable levels dating between 400 and 10,000 years ago. Sequencing analyses these ancient viruses suggested common ancestor 12,000 20,000 There is no evidence indicating that HBV was present in earliest humans as they spread out Africa; however, likely populations before farming. Furthermore, Americas...
Abstract During the Early Bronze Age, populations of western Eurasian steppe expanded across an immense area northern Eurasia. Combined archaeological and genetic evidence supports widespread Age population movements out Pontic–Caspian that resulted in gene flow vast distances, linking Yamnaya pastoralists Scandinavia with pastoral (known as Afanasievo) far to east Altai Mountains 1,2 Mongolia 3 . Although some models hold this expansion was outcome a newly mobile economy characterized by...
Abstract Archaeological and archaeogenetic evidence points to the Pontic–Caspian steppe zone between Caucasus Black Sea as crucible from which earliest pastoralist societies arose spread, ultimately influencing populations Europe Inner Asia. However, little is known about their economic foundations factors that may have contributed extensive mobility. Here, we investigate dietary proteins within dental calculus proteomes of 45 individuals spanning Neolithic Greco-Roman periods in Steppe...
Malaria-causing protozoa of the genus Plasmodium have exerted one strongest selective pressures on human genome, and resistance alleles provide biomolecular footprints that outline historical reach these species
Abstract The genetic formation of Central and South Asian populations has been unclear because an absence ancient DNA. To address this gap, we generated genome-wide data from 362 individuals, including the first eastern Iran, Turan (Uzbekistan, Turkmenistan, Tajikistan), Bronze Age Kazakhstan, Asia. Our reveal a complex set sources that ultimately combined to form ancestry Asians today. We document southward spread Eurasian Steppe, correlating with archaeologically known expansion...
The Yamnaya archaeological complex appeared around 3300BCE across the steppes north of Black and Caspian Seas, by 3000BCE reached its maximal extent from Hungary in west to Kazakhstan east. To localize ancestral geographical origins among diverse Eneolithic people that preceded them, we studied ancient DNA data 428 individuals which 299 are reported for first time, demonstrating three previously unknown genetic clines. First, a “Caucasus-Lower Volga” (CLV) Cline suffused with Caucasus...
Abstract The genetically attested migrations of the third millennium BC have made origins and nature Yamnaya culture a question broad relevance across northern Eurasia. But none key archaeological sites most important for understanding evolution is published in western languages. These include fifth-millennium Khvalynsk cemetery middle Volga steppes. When first part Eneolithic (Khvalynsk I) was discovered 1977–1979, graves displayed many material ritual traits that were quickly recognized as...
Abstract Most of the early Hungarian tribes originated from Volga-Kama and South-Ural regions, where they were composed a mixed population based on historical, philological archaeological data. We present here uniparental genetic makeup mediaeval era these regions that served as melting pot for ethnic groups with different linguistic historical backgrounds. Representing diverse cultural contexts, new data originate ancient proto-Ob-Ugric people Western Siberia (6th–13th century),...
Abstract The North Eurasian forest and forest-steppe zones have sustained millennia of sociocultural connections among northern peoples. We present genome-wide ancient DNA data for 181 individuals from this region spanning the Mesolithic, Neolithic Bronze Age. find that Early to Mid-Holocene hunter-gatherer populations across southern forest-steppes Northern Eurasia can be characterized by a continuous gradient ancestry remained stable millennia, ranging fully West in Baltic East Asian...
The arrival of farming in Europe around 8,500 years ago necessitated adaptation to new environments, pathogens, diets, and social organizations. While indirect evidence can be detected patterns genetic variation present-day people, ancient DNA makes it possible witness selection directly by analyzing samples from populations before, during after events. Here we report the first genome-wide scan for using DNA, capitalizing on largest dataset yet assembled: 230 West Eurasians dating between...
We generated genome-wide data from 69 Europeans who lived between 8,000-3,000 years ago by enriching ancient DNA libraries for a target set of almost four hundred thousand polymorphisms. Enrichment these positions decreases the sequencing required analysis median around 250-fold, allowing us to study an order magnitude more individuals than previous studies and obtain new insights about past. show that populations western far eastern Europe followed opposite trajectories 8,000-5,000 ago. At...
Abstract The invasion of Russia by the Napoleonic Grande Armée was a complete disaster. French army decimated during retreat from Russia. Thousands victims were buried in mass graves located near several cities retreat. One these discovered centre Kaliningrad (formerly Königsberg), presently most occidental oblast Russian Federation. Some skeletons revealed evidence violence related traumatic injuries. Among them, skeleton C2 belonged to young male, who had suffered serious injury lower...