A5107244129- Forensic and Genetic Research
- Gestational Diabetes Research and Management
- Birth, Development, and Health
- Archaeology and ancient environmental studies
- Pregnancy and preeclampsia studies
- Maternal and Perinatal Health Interventions
- Genetic diversity and population structure
- Bariatric Surgery and Outcomes
- Maternal and fetal healthcare
- Hepatitis B Virus Studies
- Evolution and Paleontology Studies
- Race, Genetics, and Society
- Pacific and Southeast Asian Studies
- Preterm Birth and Chorioamnionitis
- Neonatal Respiratory Health Research
- Pregnancy-related medical research
- Morphological variations and asymmetry
- Bat Biology and Ecology Studies
- Obstructive Sleep Apnea Research
- Hepatitis C virus research
- Identification and Quantification in Food
- Amazonian Archaeology and Ethnohistory
- Global Maternal and Child Health
- Assisted Reproductive Technology and Twin Pregnancy
- Maternal and Neonatal Healthcare
Max Planck Institute for Evolutionary Anthropology
2023
Universidade de São Paulo
2018-2023
Universidade do Porto
2015-2023
Max Planck Institute for the Science of Human History
2018-2021
Hospital de São João
2014-2019
i3S - Instituto de Investigação e Inovação em Saúde, Universidade do Porto
2015-2019
Saad Specialist Hospital
2019
Universidade Federal do Rio Grande do Sul
2018
Highlights•Genome-wide analysis of 49 Central and South Americans up to ∼11,000 years old•Two previously unknown genetic exchanges between North America•Distinct link a Clovis culture-associated genome the oldest Americans•Continent-wide replacement Clovis-associated ancestry beginning at least 9,000 agoSummaryWe report genome-wide ancient DNA from individuals forming four parallel time transects in Belize, Brazil, Andes, Southern Cone, each dating ∼9,000 ago. The common ancestral population...
Modern humans have populated Europe for more than 45,000 years
Ancient DNA traces the history of hepatitis B Hepatitis virus (HBV) infections represent a worldwide human health concern. To study this pathogen, Kocher et al . identified 137 remains with detectable levels dating between 400 and 10,000 years ago. Sequencing analyses these ancient viruses suggested common ancestor 12,000 20,000 There is no evidence indicating that HBV was present in earliest humans as they spread out Africa; however, likely populations before farming. Furthermore, Americas...
Different models have been proposed to elucidate the origins of founding populations America, along with number migratory waves and routes used by these first explorers. Settlements, both Pacific coast on land, evidenced in genetic archeological studies. However, origin immigrants are still controversial topics. Here, we show Australasian signal is present region, indicating a more widespread distribution within South America implicating an ancient contact between Amazonian dwellers. We...
The present study aims to understand what extent obesity is related adverse maternal, obstetrical, and neonatal outcomes in a Portuguese obstetrical population. A retrospective case-control was conducted at the Department of Obstetrics differentiated perinatal care facility. compared 1,183 obese pregnant women with 5,399 normal or underweight for occurrence gestational diabetes, hypertensive pregnancy disorders, preterm birth. Mode delivery, birthweight, intensive unit (ICU) admissions were...
Abstract Sambaqui (shellmound) societies are among the most intriguing archaeological phenomena in pre-colonial South America, extending from approximately 8,000 to 1,000 years before present (yr bp ) across 3,000 km on Atlantic coast. However, little is known about their connection early Holocene hunter-gatherers, how this may have contributed different historical pathways and processes through which late ceramists came rule coast shortly European contact. To contribute our understanding of...
South America is home to one of the most culturally diverse present-day native populations. However, dispersion pattern, genetic substructure, and demographic complexity within are still poorly understood. Based on genome-wide data 58 populations, we provide a comprehensive scenario American indigenous groups considering genomic, environmental, linguistic data. Clear patterns structure were inferred among natives, presenting at least four primary clusters in Amazonian savanna regions three...
Objective: The aim of this study was to describe the effect obesity on duration labor, specifically latent and active phases mode delivery, among nulliparous women with epidural analgesia.Study design: We conducted a retrospective cohort study, comparing sample obese (body mass index ≥30 kg/m2, n = 121) random normal weight (18.5 kg/m2 ≤body ≤25 161). Analysis included all delivered at Department Obstetrics Gynecology Centro Hospitalar, São João, Porto, Portugal between 1 January 31...
Establishing the genetic basis that underlies craniofacial variability in natural populations is one of main topics evolutionary and developmental studies. One genes associated with mammal RUNX2, present study we investigated association between length width RUNX2 across New World bats (Phyllostomidae) primates (Catarrhini Platyrrhini). Our results showed contrasting patterns glutamate/alanine ratios (Q/A ratio) palate shape these highly diverse groups. In phyllostomid bats, found an...
The relation between fertility and longevity has always been a subject of study controversy. Indeed, life expectancy extension is found to be tied late births. This conclusion can drawn from social-observational studies like the Long Life Family Study in New England Centenarian on which was that women whose last birth after 40 years age are more likely live longer. Recently, group Israel published review animal human shed some understanding cellular mechanisms behind association pregnancy...
It has generally been accepted that the current indigenous peoples of Americas are derived from ancestors northeastern Asia. The latter were believed to have spread into American continent by end Last Glacial Maximum. In this sense, a joint and in-depth study earliest settlement East Asia is required elucidate these events accurately. first Americans underwent an adaptation process Americas' vast environmental diversity, mediated biological cultural evolution niche construction, resulting in...
The administration of a single-course antenatal corticosteroid treatment is recommended for pregnant women between 24 and 34 weeks with risk premature birth. maximum effect achieved when corticosteroids are administered 24h 7 days before delivery. objective this study was to evaluate the occurrence birth within seven therapy in major obstetric situations preterm birth.Retrospective cohort including 209 hospitalized delivery, submitted fetal lung maturation. carried out January 2012 March...