A5031029583- Forensic and Genetic Research
- Forensic Anthropology and Bioarchaeology Studies
- Archaeology and ancient environmental studies
- Race, Genetics, and Society
- Genetic diversity and population structure
- Genomics and Phylogenetic Studies
- Metabolomics and Mass Spectrometry Studies
- Environmental DNA in Biodiversity Studies
- Indigenous Studies and Ecology
- Korean Peninsula Historical and Political Studies
- HIV Research and Treatment
- Image Processing and 3D Reconstruction
- vaccines and immunoinformatics approaches
- Pacific and Southeast Asian Studies
- Geology and Paleoclimatology Research
- Maritime and Coastal Archaeology
- Nutrition, Genetics, and Disease
- Yersinia bacterium, plague, ectoparasites research
- Malaria Research and Control
- Amazonian Archaeology and Ethnohistory
Max Planck Institute for Evolutionary Anthropology
2021-2024
Max Planck Institute for the Science of Human History
2017-2021
Max Planck Society
2020
Highlights•Genome-wide analysis of 49 Central and South Americans up to ∼11,000 years old•Two previously unknown genetic exchanges between North America•Distinct link a Clovis culture-associated genome the oldest Americans•Continent-wide replacement Clovis-associated ancestry beginning at least 9,000 agoSummaryWe report genome-wide ancient DNA from individuals forming four parallel time transects in Belize, Brazil, Andes, Southern Cone, each dating ∼9,000 ago. The common ancestral population...
European population history has been shaped by migrations of people, and their subsequent admixture. Recently, ancient DNA brought new insights into migration events linked to the advent agriculture, possibly spread Indo-European languages. However, little is known about north-eastern Europe, in particular populations speaking Uralic languages, such as Finns Saami. Here we analyse genomic data from 11 individuals Finland north-western Russia. We show that genetic makeup northern Europe was...
The broadening utilisation of ancient DNA to address archaeological, palaeontological, and biological questions is resulting in a rising diversity the size laboratories scale analyses being performed. In context this heterogeneous landscape, we present an advanced, entirely redesigned extended version EAGER pipeline for analysis genomic data. This Nextflow aims three main themes: accessibility adaptability different computing configurations, reproducibility ensure robust analytical...
Malaria-causing protozoa of the genus Plasmodium have exerted one strongest selective pressures on human genome, and resistance alleles provide biomolecular footprints that outline historical reach these species
Genetic studies of Neolithic and Bronze Age skeletons from Europe have provided evidence for strong population genetic changes at the beginning end period. To further understand implications these in Southern Central Europe, we analyze 96 ancient genomes Switzerland, Germany, Alsace region France, covering Middle/Late to Early Age. Similar previously described other parts early 3rd millennium BCE, detect an arrival ancestry related Late pastoralists Pontic-Caspian steppe Switzerland as...
A complex dispersal into the Caribbean The settlement of and genetic relationships among pre-European people remain a mystery. After examining 93 ancient genomes dating to range from about 3200 400 years ago, Nägele et al. suggest that at least three separate colonization events, including previously unknown wave, were connected radiation events in North America. two more lineages coexisted Cuba but fully genetically, with later movement region third group South study not only informs on...
The early Iron Age (800 to 450 BCE) in France, Germany and Switzerland, known as the 'West-Hallstattkreis', stands out featuring earliest evidence for supra-regional organization north of Alps. Often referred 'early Celtic', suggesting tentative connections later cultural phenomena, its societal population structure remain enigmatic. Here we present genomic isotope data from 31 individuals this context southern Germany, dating between 616 200 BCE. We identify multiple biologically related...
The study of ancient human genomes, archaeo- or palaeogenetics, has accelerated in the last ten years, with now thousands new genomes being released each year. Operating at interface genetics, anthro-pology and archaeology, this data includes features from all three fields, including rich meta- context-data, for example regarding spatiotemporal provenience. While archives standards genetic sequencing al-ready exist, no such infrastructure exists combined meta-data that could ensure FAIR...
Abstract Paleo-Eskimos were the first people to settle vast regions of American Arctic around 5,000 years ago, and subsequently joined largely displaced 1,000 ago by ancestors present-day Inuit Yupik. The genetic relationship between Native populations remains uncertain. We analyze ancient genome-wide data from Americas Siberia, including new Alaskan Iñupiat West Siberian populations, DNA Aleutian Islanders, northern Athabaskans, a 4,250-year-old individual Chukotkan Ust'-Belaya culture....
Tiwanaku civilization flourished in the Lake Titicaca basin between 500 and 1000 CE at its apogee influenced wide areas across southern Andes. Despite a considerable amount of archaeological data, little is known about population. We analyzed 17 low-coverage genomes from individuals dated 300 1500 demonstrated genetic continuity throughout this period, which indicates that substantial cultural political changes region were not accompanied by large-scale population movements. Conversely,...
1 Abstract The study of ancient human genomes, archaeo- or palaeogenetics, has accelerated in the last ten years, with now thousands new genomes being released each year. Operating at interface genetics, anthro-pology and archaeology, this data includes features from all three fields, including rich meta- context-data, for example regarding spatiotemporal provenience. While archives standards genetic sequencing al-ready exist, no such infrastructure exists combined meta-data that could...
Abstract Archaeological and archaeogenetic studies have highlighted the pivotal role of Caucasus region throughout prehistory, serving as a central hub for cultural, technological, linguistic innovations. However, despite its dynamic history, critical area between Greater Lesser mountain ranges, mainly corresponding to modern-day Georgia, has received limited attention. Here, we generated an ancient DNA time transect consisting 219 individuals with genome-wide data from 47 sites in this...
Abstract The broadening utilisation of ancient DNA to address archaeological, palaeontological, and biological questions is resulting in a rising diversity the size laboratories scale analyses being performed. In context this heterogeneous landscape, we present nf-core/eager, an advanced entirely redesigned extended version EAGER pipeline for analysis genomic data. This Nextflow aims three main themes: accessibility adaptability different computing configurations, reproducibility ensure...
Abstract European history has been shaped by migrations of people, and their subsequent admixture. Recently, evidence from ancient DNA brought new insights into migration events that could be linked to the advent agriculture, possibly spread Indo-European languages. However, little is known so far about population north-eastern Europe, in particular populations speaking Uralic languages, such as Finns Saami. Here we analyse genomic data 11 individuals Finland Northwest Russia. We show...
The study of ancient human genomes, archaeo- or palaeogenetics, has accelerated in the last ten years, with now thousands new genomes being released each year. Operating at interface genetics, anthro-pology and archaeology, this data includes features from all three fields, including rich meta- context-data, for example regarding spatiotemporal provenience. While archives standards genetic sequencing al-ready exist, no such infrastructure exists combined meta-data that could ensure FAIR...