A5086695835- Oceanographic and Atmospheric Processes
- Forensic Anthropology and Bioarchaeology Studies
- Climate variability and models
- Forensic and Genetic Research
- Archaeology and ancient environmental studies
- Cleft Lip and Palate Research
- Arctic and Antarctic ice dynamics
- Methane Hydrates and Related Phenomena
- Atmospheric and Environmental Gas Dynamics
- Marine and coastal ecosystems
- Endometrial and Cervical Cancer Treatments
- Cholinesterase and Neurodegenerative Diseases
- Pesticide Exposure and Toxicity
- Tracheal and airway disorders
- Yersinia bacterium, plague, ectoparasites research
- Cancer-related gene regulation
- Marine Biology and Ecology Research
- Genomics and Chromatin Dynamics
- Geological Studies and Exploration
- Paleopathology and ancient diseases
- Uterine Myomas and Treatments
- Analytical Methods in Pharmaceuticals
- Ocean Waves and Remote Sensing
- Kruppel-like factors research
- Genetic diversity and population structure
Romanian Academy
2023
University of Bucharest
2023
Pennsylvania State University
2023
University of California, Davis
2015-2020
GEOMAR Helmholtz Centre for Ocean Research Kiel
2011-2019
Johannes Gutenberg University Mainz
2013-2017
National Oceanography Centre
2016
University of California Davis Medical Center
2015
Charité - Universitätsmedizin Berlin
2007
Institut Pasteur
2006
The processes that shaped modern European mitochondrial DNA (mtDNA) variation remain unclear. initial peopling by Palaeolithic hunter-gatherers ~42,000 years ago and the immigration of Neolithic farmers into Europe ~8000 appear to have played important roles but do not explain present-day mtDNA diversity. We generated profiles 364 individuals from prehistoric cultures in Central perform a chronological study, spanning Early Bronze Age (5500 1550 calibrated before common era). used this...
published or not.The documents may come from teaching and research institutions in France abroad, public private centers.
Expression of AP-2 transcription factors has been detected previously in embryonic renal tissues. We show here that AP-2β −/− mice complete development and die at postnatal days 1 2 because polycystic kidney disease. Analyses revealed induction epithelial conversion, mesenchyme condensation, further glomerular tubular differentiation occur normally AP-2β-deficient mice. At the end expression bcl-X L , bcl-w, bcl-2 is down-regulated parallel to massive apoptotic death collecting duct distal...
In this paper we compare the simulated Arctic Ocean in 15 global ocean–sea ice models framework of Coordinated Ocean-ice Reference Experiments, phase II (CORE-II). Most these are ocean and sea-ice components coupled climate used Coupled Model Intercomparison Project Phase 5 (CMIP5) experiments. We mainly focus on hydrography interior, state Atlantic Water layer heat volume transports at gateways Davis Strait, Bering Fram Strait Barents Sea Opening. found that there is a large spread...
In 2005 to 2007 45 skeletons of adults and subadults were excavated at the Lombard period cemetery Szólád (6th century A.D.), Hungary. Embedded into well-recorded historical context, article presents results obtained by an integrative investigation including anthropological, molecular genetic isotopic (δ15N, δ13C, 87Sr/86Sr) analyses. Skeletal stress markers as well traces interpersonal violence found occur frequently. The mitochondrial DNA profiles revealed a heterogeneous spectrum lineages...
The analysis of the human remains from megalithic tomb at Alto de Reinoso represents widest integrative study a Neolithic collective burial in Spain. Combining archaeology, osteology, molecular genetics and stable isotope (87Sr/86Sr, δ15N, δ13C) it provides wealth information on minimum number individuals, age, sex, body height, pathologies, mitochondrial DNA profiles, kinship relations, mobility, diet. grave was use for approximately one hundred years around 3700 cal BC, thus dating Late...
Abstract. The Agulhas Current, the western boundary current of South Indian Ocean, has been shown to play an important role in connectivity between and Atlantic oceans. greater Current system is highly dominated by mesoscale dynamics. To investigate their influence on regional global circulations, a family high-resolution ocean general circulation model configurations based NEMO code developed. Horizontal resolution refinement achieved embedding “nests” covering oceans at 1/10∘ (INALT10)...
Abstract Agriculture first reached the Iberian Peninsula around 5700 BCE. However, little is known about genetic structure and changes of prehistoric populations in different geographic areas Iberia. In our study, we focus on maternal makeup Neolithic (~ 5500–3000 BCE), Chalcolithic 3000–2200 BCE) Early Bronze Age 2200–1500 BCE). We report ancient mitochondrial DNA results 213 individuals (151 HVS-I sequences) from northeast, central, southeast southwest regions thus largest archaeogenetic...
Patients with cleft palate and other causes of velopharyngeal insufficiency (VPI) suffer adverse effects on social interactions communication. Measurement these patient-reported outcomes is needed to help guide surgical nonsurgical care.
AP-2 transcription factors have been suggested to exert key regulatory functions in vertebrate embryonic development, tumorigenicity of various cancer cell types, and controlling cycle apoptotic effector genes. In this study, we investigated transcriptional regulation the AP-2α gene promoter mediated by an autoregulatory element (referred as A32) with a core consensus binding site at position −336 relative mRNA initiation site. multiple different nuclear proteins HeLa Neuro2A extracts form...
Velopharyngeal insufficiency in children with cleft palate (and other causes) contributes to difficulty communication and quality of life. The pharyngeal flap is a workhorse address hypernasality nasal air escape. However, there paucity literature on the characteristics cases that require revision.To measure revision rate flaps, compare preperceptual postperceptual speech scores, identify those patients who required revision.A retrospective medical record review was completed for underwent...
We generated genome-wide data from 69 Europeans who lived between 8,000-3,000 years ago by enriching ancient DNA libraries for a target set of almost four hundred thousand polymorphisms. Enrichment these positions decreases the sequencing required analysis median around 250-fold, allowing us to study an order magnitude more individuals than previous studies and obtain new insights about past. show that populations western far eastern Europe followed opposite trajectories 8,000-5,000 ago. At...
Abstract Recent evidence from mooring data in the equatorial Atlantic reveals that semiannual and longer time scale ocean current variability is close to being resonant with basin modes. Here we show intraseasonal variability, scales of tens days, provides energy maintain these modes against dissipation. The mechanism analogous by which storm systems atmosphere act atmospheric jet stream. We demonstrate using an idealized model setup exhibits deep jets. results are supported direct analysis...
Abstract. The Agulhas Current, the western boundary current of South Indian Ocean, has been shown to play an important role in connectivity between and Atlantic oceans. greater Current system is highly dominated by mesoscale dynamics. To investigate their influence onto regional global circulations, a family high-resolution ocean general circulation model configurations based on NEMO code developed. Horizontal resolution refinement achieved embedding nests covering oceans at 1/10° (INALT10)...
Quality of life (QOL) assessments are useful tools that measure a patient's health status and monitor patient-reported outcome measures. This study highlights the process linguistic validation QOL assessment to serve Spanish-speaking families ultimately help decrease language barriers in treatment velopharyngeal insufficiency (VPI).The standardized included forward backward translation, reconciliation, cognitive interviews with patients families. Preliminary instrument test-retest...