A5029444442- Advanced Radiotherapy Techniques
- Head and Neck Cancer Studies
- Glioma Diagnosis and Treatment
- Lung Cancer Treatments and Mutations
- Lung Cancer Diagnosis and Treatment
- Medical Imaging Techniques and Applications
- Radiomics and Machine Learning in Medical Imaging
- Brain Metastases and Treatment
- Prostate Cancer Diagnosis and Treatment
- Sarcoma Diagnosis and Treatment
- Prostate Cancer Treatment and Research
- Management of metastatic bone disease
- Cancer Diagnosis and Treatment
- Colorectal and Anal Carcinomas
- Cancer Genomics and Diagnostics
- Ultrasound and Hyperthermia Applications
- Head and Neck Surgical Oncology
- Radiation Therapy and Dosimetry
- Endometrial and Cervical Cancer Treatments
- Cancer, Hypoxia, and Metabolism
- Lung Cancer Research Studies
- Radiopharmaceutical Chemistry and Applications
- Meningioma and schwannoma management
- Gastric Cancer Management and Outcomes
- Salivary Gland Tumors Diagnosis and Treatment
Charité - Universitätsmedizin Berlin
2015-2024
Humboldt-Universität zu Berlin
2002-2024
Freie Universität Berlin
2017-2024
Heidelberg University
2014-2023
DKFZ-ZMBH Alliance
2023
Ihre-Radiologen
2023
European Organisation for Research and Treatment of Cancer
2009-2022
Klinik und Poliklinik für Strahlentherapie und Radioonkologie
1989-2022
Deutschen Konsortium für Translationale Krebsforschung
2014-2022
German Cancer Research Center
2014-2022
Therapy options at the time of recurrence glioblastoma multiforme are often limited. We investigated whether treatment with a new intratumoral thermotherapy procedure using magnetic nanoparticles improves survival outcome. In single-arm study in two centers, 66 patients (59 recurrent glioblastoma) received neuronavigationally controlled instillation an aqueous dispersion iron-oxide (magnetite) and subsequent heating particles alternating field. Treatment was combined fractionated...
The effect of internal mammary and medial supraclavicular lymph-node irradiation (regional nodal irradiation) added to whole-breast or thoracic-wall after surgery on survival among women with early-stage breast cancer is unknown.We randomly assigned who had a centrally medially located primary tumor, irrespective axillary involvement, an externally tumor involvement undergo either in addition regional (nodal-irradiation group) alone (control group). end point was overall survival. Secondary...
The role of adjuvant chemoradiotherapy (CRT) in resectable pancreatic cancer is still debated. This randomized phase II intergroup study explores the feasibility and tolerability a gemcitabine-based CRT regimen after R0 resection head cancer.Within 8 weeks surgery, patients were randomly assigned to receive either four cycles gemcitabine (control arm) or for two followed by weekly with concurrent radiation (50.4 Gy; arm). primary objective was exclude < 60% treatment completion > 40% rate...
Bei diesem Dokument handelt es sich um die aktualisierte Fassung der 2006 erstmals erstellten S3-Leitlinie zum exokrinen Pankreaskarzinom.
Hyperthermia has been shown to improve the effectiveness of chemotherapy and radiotherapy in treatment cancer. This paper summarises all recent clinical trials registered ClinicalTrials.gov registry.The records 175,538 at were downloaded on 29 September 2014 a database was established. We searched this for hyperthermia or equivalent words.A total 109 identified which part regimen. Of these, 49 (45%) had hyperthermic intraperitoneal after cytoreductive surgery (HIPEC) as primary intervention,...
We examined the prognostic value of tumour-infiltrating lymphocytes (TILs) in patients with squamous cell carcinoma head and neck (SCCHN) after surgery postoperative cisplatin-based chemoradiotherapy. FFPE-tissue originating from 161 treated 8 DKTK partner sites was immunohistochemically stained for CD3 CD8. Their expression correlated clinicopathological characteristics as well overall survival (OS), local progression-free (LPFS) distant metastases free-survival (DMFS), also context...
Radiomics applies machine learning algorithms to quantitative imaging data characterise the tumour phenotype and predict clinical outcome. For development of radiomics risk models, a variety different is available it not clear which one gives optimal results. Therefore, we assessed performance 11 combined with 12 feature selection methods by concordance index (C-Index), loco-regional control (LRC) overall survival for patients head neck squamous cell carcinoma. The considered are able deal...
PURPOSE To evaluate the feasibility and efficacy of an intensive multimodality approach with combination chemotherapy, hyperfractionated accelerated chemoradiotherapy, definitive surgery in prognostically unfavorable subgroups locally advanced non-small-cell lung cancer stages IIIA IIIB (LAD-NSCLC). PATIENTS AND METHODS Following staging, including mediastinoscopy, 94 patients inoperable LAD-NSCLC were treated preoperatively chemotherapy (three courses split-dose cisplatin etoposide [PE])...
To report the results and corresponding acute late reactions of a prospective, randomized, clinical study in locally advanced head neck cancer comparing concurrent fluorouracil (FU) mitomycin (MMC) chemotherapy hyperfractionated accelerated radiation therapy (C-HART; 70.6 Gy) to alone (HART; 77.6 Gy).Three hundred eighty-four stage III (6%) IV (94%) oropharyngeal (59.4%), hypopharyngeal (32.3%), oral cavity (8.3%) patients were randomly assigned receive either 30 Gy (2 every day) followed by...
PURPOSE: Relapse pattern and late toxicities in long-term survivors were analyzed after the introduction of prophylactic cranial irradiation (PCI) into a phase II trial on trimodality treatment locally advanced (LAD) non–small-cell lung cancer (NSCLC). PATIENTS AND METHODS: Seventy-five patients with stage IIIA(N2)/IIIB NSCLC treated induction chemotherapy, preoperative radiochemotherapy, surgery. PCI was routinely offered during second period study accrual. Patients given total radiation...