A5011941570- T-cell and B-cell Immunology
- Immune Cell Function and Interaction
- HIV Research and Treatment
- Vector-borne infectious diseases
- Viral Infections and Vectors
- Insect and Pesticide Research
- Liver Disease Diagnosis and Treatment
- Liver physiology and pathology
- Invertebrate Immune Response Mechanisms
- Liver Disease and Transplantation
- Peroxisome Proliferator-Activated Receptors
- Congenital Anomalies and Fetal Surgery
- Peptidase Inhibition and Analysis
- Metabolism, Diabetes, and Cancer
- Alcohol Consumption and Health Effects
- Interstitial Lung Diseases and Idiopathic Pulmonary Fibrosis
- TGF-β signaling in diseases
- Signaling Pathways in Disease
- Business, Innovation, and Economy
- Allergic Rhinitis and Sensitization
- Celiac Disease Research and Management
- Bird parasitology and diseases
- interferon and immune responses
- Parasitic infections in humans and animals
- Influenza Virus Research Studies
National Institute of Genomic Medicine
2011-2016
Universidad Nacional Autónoma de México
1996-2012
Mayo Clinic
2000-2003
National Institute of Environmental Health Sciences
1993
Instituto Nacional de Cancerología
1993
An important step of innate immune response is the recruitment polymorphonuclear leukocytes (PMN) to injured tissues through chemotactic molecules. Galectins, a family endogenous lectins, participate in numerous functions such as lymphoid cell migration, homing, cell-cell and cell-matrix interactions. Particularly, galectin-3 (Gal-3) -9 have been implicated modulation acute chronic inflammation by inducing directional migration monocytes/macrophages eosinophils, whereas Gal-1 considered...
It has been proposed that lipid peroxidation (LP) might be a modulator of cell division, influencing initiation and cessation mitosis in regenerating liver. However, the understanding participating role this event onset liver proliferation hampered by fact both higher or lower LP have reported after two–thirds partial hepatectomy (PH). Therefore, present study deals with extent main subcellular fractions from rat at early stages regeneration, induced either PH 70% acute CCl4 administration....
We examined the role of cytokines gamma interferon (IFN-gamma) and interleukin-12 (IL-12) in model acute babesiosis with WA1 Babesia. Mice genetically deficient IFN-gamma-mediated responses (IFNGR2KO mice) IL-12-mediated (Stat4KO were infected Babesia, observations made on course infection cytokine responses. Levels IFN-gamma IL-12 serum increased 24 h after parasite inoculation. The augmented susceptibility observed IFNGR2KO Stat-4KO mice suggests that early IL-12- are involved protection...
ABSTRACT Infection of severe combined immunodeficient mice with Babesia sp. strain WA1 was studied to assess the contributions innate and adaptive immunity in resistance acute babesiosis. The scid mutation showed little effect genetically susceptible C3H did not decrease inherent C57BL/6 infection, suggesting that plays a central role determining course infection these strains. In contrast, dramatically impaired moderately BALB/c mice, acquired may play an important secondary role....
Human central memory CD4 T cells are characterized by their capacity of proliferation and differentiation into effector cells. Homeostasis is considered a key factor sustaining the asymptomatic stage Immunodeficiency Virus type 1 (HIV-1) infection, while progression to acquired immunodeficiency syndrome imputed homeostatic failure. We investigated if from patients with HIV-1 infection have gene expression profile impeding survival, despite activated state. Using microarrays, we analyzed mRNA...
There is an important set of cirrhotic and diabetic patients that present both diseases. However, information about metabolic cellular blood markers are altered, in conjunction or distinctively, the 3 pathological conditions scarce. The aim this project was to evaluate several indicators prooxidant reactions membrane composition samples (serum red cells (RBCs)) from clinically classified as (<mml:math xmlns:mml="http://www.w3.org/1998/Math/MathML"...
Human neurocysticercosis (NC) caused by Taenia solium is a parasitic disease of the central nervous system that endemic in many developing countries. In this study, genetic approach using murine intraperitoneal cysticercosis related cestode crassiceps was employed to identify host factors regulate establishment and proliferation parasite. A/J mice are permissive T. infection while C57BL/6J (B6) comparatively restrictive, with 10-fold difference numbers peritoneal cysticerci recovered 30 days...
Lung fibrosis has been postulated to be mediated by the production of macrophage-derived growth factors that are both mitogenic and chemotactic for fibroblasts. In vitro studies from our laboratory demonstrated alveolar interstitial macrophages treated with iron asbestos release platelet-derived factor (PDGF) transforming factor-β (TGF-β) into media. This conditioned media was capable inducing proliferation Chemotaxis primary rat lung fibroblasts (RLF). TGF-β is known present in media, RLF...
It has been proposed that lipid peroxidation (LP) might be a modulator of cell division, influencing initiation and cessation mitosis in regenerating liver. However, the understanding participating role this event onset liver proliferation hampered by fact both higher or lower LP have reported after two-thirds partial hepatectomy (PH). Therefore, present study deals with extent main subcellular fractions from rat at early stages regeneration, induced either PH 70% acute CCl4 administration....
México fue pionero en establecer catálogos para identificar y hacer asequibles insumos médicos la atención de su población, incluyendo medicamentos, instrumental, equipos material curación. Hace medio siglo, 1971, surgió el Instituto Mexicano del Seguro Social iniciativa llamado Cuadro Básico, que se constituyó como una herramienta fun-damental funcionamiento las instituciones públicas salud, con cual establecieron listados probada eficacia seguridad, claves administrativas asignadas...