A5080553084- Health disparities and outcomes
- Aging and Gerontology Research
- Mental Health Treatment and Access
- Pancreatic and Hepatic Oncology Research
- Dementia and Cognitive Impairment Research
- Health and Well-being Studies
- Sarcoma Diagnosis and Treatment
- Mental Health and Psychiatry
- Religion, Spirituality, and Psychology
- Substance Abuse Treatment and Outcomes
- Treatment of Major Depression
- Gastric Cancer Management and Outcomes
- Child and Adolescent Psychosocial and Emotional Development
- Schizophrenia research and treatment
- Mental Health Research Topics
- Cardiac Health and Mental Health
- Cholangiocarcinoma and Gallbladder Cancer Studies
- Geriatric Care and Nursing Homes
- Health and Wellbeing Research
- Neuroendocrine Tumor Research Advances
- Health Systems, Economic Evaluations, Quality of Life
- Psychological Well-being and Life Satisfaction
- Gastrointestinal Tumor Research and Treatment
- Health, psychology, and well-being
- Bone Tumor Diagnosis and Treatments
Duke University
2016-2025
Duke University Hospital
2015-2025
Duke Medical Center
2015-2024
Society of Surgical Oncology
2024
Indiana University – Purdue University Indianapolis
2023
National Cancer Registration Service
2023
Institut de Virologie
2020-2022
BlazeTech (United States)
2022
Duke Cancer Institute
2018-2022
RELX Group (Netherlands)
2022
Journal Article A Short Physical Performance Battery Assessing Lower Extremity Function: Association With Self-Reported Disability and Prediction of Mortality Nursing Home Admission Get access Jack M. Guralnik, Guralnik 1Epidemiology, Demography, Biometry Program, National Institutes on Aging, Health, BethesdaMaryland Search for other works by this author on: Oxford Academic PubMed Google Scholar Eleanor Simonsick, Simonsick Luigi Ferrucci, Ferrucci 2Geriatric Department, Hospital I...
Journal Article Loneliness: A Source Book of Current Theory, Research and Therapy Get access Therapy, by L. A. Peplau & D. Perlman. John Wiley Sons, New York, 1982, 430 pp., $37.95 (hardcover) Stressful Life Events, Social Support Networks, Gerontological Health, T. H. Wan. Lexington Books, Lexington, MA, 151 $19.95 (hardcover). Isolated Elders: Health Intervention, E. Rathbone-McCuan J. Hashimi. Aspen Publishing, Rockville, MD, 324 $27.95 Dan Blazer, II, MD Department Psychiatry, Duke...
The frequencies of five common sleep complaints—trouble falling asleep, waking up, awaking too early, needing to nap and not feeling rested—were assessed in over 9,000 participants aged 65 years older the National Institute on Aging's multicentered study entitled "Established Populations for Epidemiologic Studies Elderly" (EPESE). Less than 20% each community rarely or never had any complaints, whereas half reported at least one these complaints as occurring most time. Between 23% 34%...
Major depression is a frequent and disabling psychiatric disorder in the United States. This report examines prevalence risk factor profile of both pure comorbid major according to data from National Comorbidity Survey.To estimate comorbidity States, national sample 8,098 persons 15-54 years age 48 conterminous states was surveyed with modified version Composite International Diagnostic Interview.From survey current (30-day) estimated be 4.9%, relatively higher females, young adults, less...
General population data are presented on the prevalence and correlates of comorbidity between DSM-III-R major depressive disorder (MDD) other disorders. The come from US National Comorbidity Survey, a large general survey persons aged 15-54 years in non-institutionalised civilian population. Diagnoses based modified version Composite International Diagnostic Interview (CIDI). analysis shows that most cases lifetime MDD secondary. In sense they occur people with prior history another...
A community sample made in the fall of 1972 Durham County, North Carolina, and that consisted 331 persons 65 years age older was assessed for adequacy social support along three parameters: roles available attachments, perceived support, frequency interaction. This approach to assessment complements previous approaches measurement which have not compared with various components construct. Mortality status, outcome variable, determined 30 months after initial assessment. The crude relative...
To help adapt cardiovascular disease risk prediction approaches to low-income and middle-income countries, WHO has convened an effort develop, evaluate, illustrate revised models. Here, we report the derivation, validation, illustration of charts that have been adapted circumstances 21 global regions.
Objective: The authors' goal was to characterize the clinical and demographic features of vascular depression.Method: They classified 89 depressed patients into two groups-those with (N=32) nonvascular (N=57) depression-on basis examination brain magnetic resonance images.All were enrolled in National Institute Mental Health Clinical Research Center for Study Depression Later Life, located at Duke University.The depression compared on several risk factors.Results: Bivariate analyses a fully...
BackgroundLow-risk limits recommended for alcohol consumption vary substantially across different national guidelines. To define thresholds associated with lowest risk all-cause mortality and cardiovascular disease, we studied individual-participant data from 599 912 current drinkers without previous disease.MethodsWe did a combined analysis of three large-scale sources in 19 high-income countries (the Emerging Risk Factors Collaboration, EPIC-CVD, the UK Biobank). We characterised...
Advanced age among the elderly has been hypothesized to be a risk factor for depression, yet extant data do not uniformly support this hypothesis. The paucity of sufficiently large and representative samples both young-old old-old failure control critical variables known confound association between advanced depression have prevented testing duke EPESE (Establishment Of A Population For Epidemiologic Studies Elderly) assessed 3,998 community-dwelling elders (65+)for depressive symptoms using...
Journal Article The Epidemiology of Depression in an Elderly Community Population Get access Dan Blazer, MD, PhD, PhD 2Department Psychiatry and Center for the Study AgingBox 3215Duke University Medical CenterDurham, NC 27710 Search other works by this author on: Oxford Academic PubMed Google Scholar Dana C. Hughes, Linda K. George, Gerontologist, Volume 27, Issue 3, June 1987, Pages 281–287, https://doi.org/10.1093/geront/27.3.281 Published: 01 1987
Results on the age/sex specific prevalence of DSM-III affective disorders from NIMH Epidemiologic Catchment Area Study (ECA), a probability sample over 18,000 adults five United States communities, are presented. The cross-site means for bipolar disorder ranged 0.7/100 (2 weeks) to 1.2/100 (lifetime), with mean age onset 21 years and no sex difference in rates. major depression 1.5/100 4.4/100 27 higher rates women. dysthymia, chronic condition, was 3.1/100 rate There reasonable consistency...
Background: Several sets of diagnostic criteria have been published for vascular dementia since the 1960s. The continuing ambiguity in definition warrants a critical reexamination. Methods: Participants at special symposium International Society Vascular Behavioral and Cognitive Disorders (VASCOG) 2009 critiqued current criteria. They drafted proposal new set criteria, later reviewed through multiple drafts by group, including additional experts members Neurocognitive Work Group fifth...
The authors surveyed 997 elderly people living in the community and found that rate of significant dysphoric symptomatology was 14.7%. Forty-five (4.5%) these individuals suffered from symptoms only, 37 (3.7%) had a major depressive disorder. Eighteen (1.8%) primary disorder 19 (1.9%) secondary Sixty-five (6.5%) associated with impaired physical health. frequency widowhood, impairment social resources, economic resources greater for entire sample used psychiatric services at very low rate.
The primary goal of this study was to evaluate whether pathologic response chemotherapy predicts patient survival after preoperative and resection colorectal liver metastases (CLM). secondary the identify clinical predictors response.A retrospective review performed 305 patients who underwent irinotecan- or oxaliplatin-based chemotherapy, followed by CLM. Pathologic systematically evaluated reported as mean percentage cancer cells remaining within each tumor. Univariate multivariate analyses...
OBJECTIVES. The purpose of these analyses was to test the hypothesis that depressive symptomatology affects risk onset physical disability in high-functioning elderly adults. METHODS. data come from MacArthur Study Successful Aging, a community-based cohort adults aged 70 through 79 years who were assessed twice at 2.5-year interval. Physical and cognitive status by performance as well self-report measures. RESULTS. In gender-stratified logistic regression models, high symptoms measured...
The investigators examined the frequency of religious coping among older medical inpatients, characteristics those who use it, and relation between this behavior depression.The subjects were 850 men aged 65 years over, without psychiatric diagnoses, consecutively admitted to or neurological services a southern Veterans Administration center. Religious was assessed with three-item index. Depressive symptoms by self-rating (the Geriatric Depression Scale) observer rating Hamilton Rating Scale...
Performance-based measures of physical performance were examined for an older cohort relatively high-functioning men and women. Relationships between baseline sociodemographic health status characteristics also examined. Three-year pattern changes in are described, predictors change investigated A women, aged 70–79, was identified 1988 by subsampling from three community-based studies on the basis cognitive function. Baseline in-home assessments included tests measurement status. summary...
Persons of low socioeconomic status are known to have reduced life expectancy. In a study the relation disability-free or active expectancy among older persons, we analyzed prospectively gathered data on 2219 blacks and 1838 whites who were 65 years age in Piedmont region North Carolina. We defined disability as inability perform independently one more basic functional activities such walking, bathing, dressing, eating, using toilet. For subgroups by sex, race, education, statistical models...