Thomas A. Gaziano

ORCID: 0000-0002-5985-345X
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About
Contact & Profiles
Research Areas
  • Global Public Health Policies and Epidemiology
  • Health Systems, Economic Evaluations, Quality of Life
  • Blood Pressure and Hypertension Studies
  • Obesity, Physical Activity, Diet
  • Nutritional Studies and Diet
  • Cardiovascular Health and Risk Factors
  • Health Promotion and Cardiovascular Prevention
  • Diabetes, Cardiovascular Risks, and Lipoproteins
  • Global Health Care Issues
  • Chronic Disease Management Strategies
  • Lipoproteins and Cardiovascular Health
  • Medication Adherence and Compliance
  • Heart Failure Treatment and Management
  • Cardiac Health and Mental Health
  • Pharmaceutical Economics and Policy
  • Healthcare Systems and Reforms
  • Global Health and Epidemiology
  • Cardiovascular Function and Risk Factors
  • Cardiac pacing and defibrillation studies
  • Health disparities and outcomes
  • Clinical practice guidelines implementation
  • Streptococcal Infections and Treatments
  • Mobile Health and mHealth Applications
  • Sodium Intake and Health
  • Healthcare Policy and Management

Brigham and Women's Hospital
2016-2025

Harvard University
2016-2025

Mass General Brigham
2024

University of the Witwatersrand
2017-2023

University of London
2023

London School of Hygiene & Tropical Medicine
2023

Harvard University Press
2010-2023

ORCID
2022

Boston University
2010-2022

Tufts University
2016-2018

Stephen Kaptoge Lisa Pennells Dirk De Bacquer Marie Therese Cooney Maryam Kavousi and 95 more Gretchen A Stevens Leanne M Riley Stefan Savin Taskeen Khan Servet Altay Philippe Amouyel Gerd Assmann Steven Bell Yoav Ben‐Shlomo Lisa Berkman Joline W. J. Beulens Cecilia Björkelund Michael J. Blaha Dan G. Blazer Thomas Bolton R. Beaglehole Hermann Brenner Eric J. Brunner Edoardo Casiglia Parinya Chamnan Yeun-Hyang Choi Rajiv Chowdry Sean Coady Carlos J. Crespo Mary Cushman Gilles R. Dagenais Ralph B. D’Agostino Makoto Daimon Karina W. Davidson Gunnar Engström Ian Ford John Gallacher Ron T. Gansevoort Thomas A. Gaziano Simona Giampaoli Greg Grandits Sameline Grimsgaard Diederick E. Grobbee Vilmundur Guðnason Qi Guo Hanna Tolonen Steve E. Humphries Hiroyasu Iso J. Wouter Jukema Jussi Kauhanen André Pascal Kengne Davood Khalili Wolfgang Köenig Daan Kromhout Harlan M. Krumholz TH Lam Gail A. Laughlin Alejandro Marín Ibañez Tom Meade Karel G.M. Moons Paul J. Nietert Toshiharu Ninomiya Børge G. Nordestgaard Christopher J. O’Donnell Luigi Palmieri Anushka Patel Pablo Perel Jackie F. Price Rui Providência Paul M. Ridker Beatriz L. Rodríguez Annika Rosengren Ronan Roussel Masaru Sakurai Veikko Salomaa Shinichi Sato Ben Schöttker Nawar Shara Jonathan E Shaw Hee-Choon Shin Leon A. Simons Eleni Sofianopoulou Johan Sundström Henry Völzke Robert B. Wallace Nicholas J. Wareham Peter Willeit David A. Wood Angela Wood Dong Zhao Mark Woodward Goodarz Danaei Gregory A. Roth Shanthi Mendis Oyere Onuma Cherian Varghese Majid Ezzati Ian Graham Rod Jackson John Danesh

To help adapt cardiovascular disease risk prediction approaches to low-income and middle-income countries, WHO has convened an effort develop, evaluate, illustrate revised models. Here, we report the derivation, validation, illustration of charts that have been adapted circumstances 21 global regions.

10.1016/s2214-109x(19)30318-3 article EN cc-by The Lancet Global Health 2019-09-02

Cardiovascular disease (CVD) has become the number-one cause of death in developing world. This epidemic potential to place a large social and economic burden on countries, where CVD tends strike those their prime working years. Since resources for managing are limited, it is important that interventions be guided by cost-effectiveness results low- middle-income countries. Despite burden, cost-effective strategies exist at population individual levels reducing CVD. Integral all personal...

10.1377/hlthaff.26.1.13 article EN Health Affairs 2007-01-01

Suboptimal blood pressure including established nonoptimal has been shown to have significant economic consequences in developed countries. However, no exhaustive study done evaluate its potential costs, globally. We, therefore, set out estimate the global cost of pressure.Estimates for healthcare costs attributed suboptimal those over age 30 were made all World Bank regions. Annual and 10-year estimates using Markov models treating main sequelae: stroke myocardial infarction.Suboptimal...

10.1097/hjh.0b013e32832a9ba3 article EN Journal of Hypertension 2009-06-18

To estimate individual and household economic impact of cardiovascular disease (CVD) in selected low- middle-income countries (LMIC).Empirical evidence on the microeconomic consequences CVD LMIC is scarce.We surveyed 1,657 recently hospitalized patients (66% male; mean age 55.8 years) from Argentina, China, India, Tanzania to evaluate functional/productivity hospitalization. Respondents were stratified into three income groups. Median out-of-pocket expenditures for treatment over 15 month...

10.1371/journal.pone.0020821 article EN cc-by PLoS ONE 2011-06-14

The American College of Cardiology and the Heart Association (ACC/AHA) cholesterol treatment guidelines have wide-scale implications for treating adults without history atherosclerotic cardiovascular disease (ASCVD) with statins.To estimate cost-effectiveness various 10-year ASCVD risk thresholds that could be used in ACC/AHA guidelines.Microsimulation model, including lifetime time horizon, US societal perspective, 3% discount rate costs, health outcomes. In hypothetical individuals from a...

10.1001/jama.2015.6822 article EN JAMA 2015-07-14
Katherine Wilemon Jasmine Patel Carlos A. Aguilar‐Salinas Catherine D. Ahmed Mutaz Al-Khnifsawi and 84 more Wael Almahmeed Rodrigo Alonso Khalid Al‐Rasadi Lina Badimón Luz Mery Bernal Martin P. Bogsrud Lynne T. Braun Liam R. Brunham Alberico L. Catapano Kristýna Cillíková Pablo Corral Regina Cuevas Joep C. Defesche Olivier Descamps Sarah D. de Ferranti Jean-Luc Eiselé Gerardo Elikir Emanuela Folco Tomáš Freiberger Francesco Fuggetta Isabel Gaspar Ákos G. Gesztes Urh Grošelj Ian Hamilton‐Craig Gabriele Hanauer-Mader Mariko Harada‐Shiba G. E. Hastings G. Kees Hovingh Maria Cristina de Oliveira Izar Allison Jamison Gunnar N. Karlsson Meral Kayıkçıoğlu Sue Koob Masahiro Koseki Stacey Lane Marcos M. Lima-Martínez Greizy López Tânia Leme da Rocha Martinez David Marais Letrillart Marion Pedro Mata Inese Maurina Diana Maxwell Roopa Mehta George A. Mensah André R. Miserez Dermot Neely Stephen J. Nicholls Atsushi Nohara Børge G. Nordestgaard Leiv Ose Athanasios Pallidis Jing Pang Jules Payne Amy L. Peterson Monica P. Popescu Raman Puri Kausik K. Ray Ashraf Reda Tiziana Sampietro Raúl D. Santos Inge Schalkers Laura Schreier Michael D. Shapiro Eric J.G. Sijbrands Daniel Soffer Claudia Stefanutti Mario Stoll Rody G. Sy Marta Lucía Tamayo Myra Tilney Lâle Tokgözoğlu Brian Tomlinson Antonio J. Vallejo‐Vaz Alejandra Vázquez-Cárdenas Patrícia Vieira de Luca David S Wald Gerald F. Watts Nanette K. Wenger M. Allison Wolf David A. Wood Aram Zegerius Thomas A. Gaziano Samuel S. Gidding

<h3>Importance</h3> Familial hypercholesterolemia (FH) is an underdiagnosed and undertreated genetic disorder that leads to premature morbidity mortality due atherosclerotic cardiovascular disease. affects 1 in 200 250 people around the world of every race ethnicity. The lack general awareness FH among public medical community has resulted only 10% population being diagnosed adequately treated. World Health Organization recognized as a health priority 1998 during consultation meeting Geneva,...

10.1001/jamacardio.2019.5173 article EN JAMA Cardiology 2020-01-02

In 2011, the United Nations set key targets to reach by 2025 reduce risk of premature noncommunicable disease death 25% 2025. With cardiovascular being largest contributor global mortality, accounting for nearly half 36 million annual deaths, achieving goal requires that and its factors be aggressively addressed. The Global Cardiovascular Disease Taskforce, comprising World Heart Federation, American Association, College Cardiology Foundation, European Network, Society Cardiology, with...

10.1161/cir.0000000000000395 article EN Circulation 2016-05-10

Hypertension is a major cause of cardiovascular disease and deaths worldwide especially in low- middle-income countries. Despite the availability safe, well-tolerated, cost-effective blood pressure (BP)-lowering therapies, &lt;14% adults with hypertension have BP controlled to systolic/diastolic &lt;140/90 mm Hg. We report new treatment guidelines, developed accordance World Health Organization Handbook for Guideline Development. Overviews reviews evidence were conducted summary tables...

10.1161/hypertensionaha.121.18192 article EN cc-by Hypertension 2021-11-15

Cardiovascular diseases (CVDs) are the leading cause of mortality globally.Of 20.5 million CVD-related deaths in 2021, approximately 80% occurred low-and middleincome countries.Using data from Global Burden Disease Study, NCD Risk Factor Collaboration, Countdown initiative, WHO Health Observatory, and Expenditure database, we present burden CVDs, associated risk factors, their association with national health expenditures, an index critical policy implementation.The Central Europe, Eastern...

10.5334/gh.1288 article EN cc-by Global Heart 2024-01-01

Objectives To determine the prevalence and treatment status of hypertension in South Africa. Design National cross-sectional survey. Setting 13 802 randomly selected Africans, 15 years older, were visited their homes 1998. Methods Trained fieldworkers completed questionnaires on lifestyle chronic diseases, measured blood pressure with an Omron manometer recorded drug utilization. Drugs classified using Anatomical Therapeutic Chemical index. Results The mean systolic for men women was 123...

10.1097/00004872-200110000-00004 article EN Journal of Hypertension 2001-10-01
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