- Global Public Health Policies and Epidemiology
- Health Systems, Economic Evaluations, Quality of Life
- Blood Pressure and Hypertension Studies
- Obesity, Physical Activity, Diet
- Nutritional Studies and Diet
- Cardiovascular Health and Risk Factors
- Health Promotion and Cardiovascular Prevention
- Diabetes, Cardiovascular Risks, and Lipoproteins
- Global Health Care Issues
- Chronic Disease Management Strategies
- Lipoproteins and Cardiovascular Health
- Medication Adherence and Compliance
- Heart Failure Treatment and Management
- Cardiac Health and Mental Health
- Pharmaceutical Economics and Policy
- Healthcare Systems and Reforms
- Global Health and Epidemiology
- Cardiovascular Function and Risk Factors
- Cardiac pacing and defibrillation studies
- Health disparities and outcomes
- Clinical practice guidelines implementation
- Streptococcal Infections and Treatments
- Mobile Health and mHealth Applications
- Sodium Intake and Health
- Healthcare Policy and Management
Brigham and Women's Hospital
2016-2025
Harvard University
2016-2025
Mass General Brigham
2024
University of the Witwatersrand
2017-2023
University of London
2023
London School of Hygiene & Tropical Medicine
2023
Harvard University Press
2010-2023
ORCID
2022
Boston University
2010-2022
Tufts University
2016-2018
To help adapt cardiovascular disease risk prediction approaches to low-income and middle-income countries, WHO has convened an effort develop, evaluate, illustrate revised models. Here, we report the derivation, validation, illustration of charts that have been adapted circumstances 21 global regions.
Cardiovascular disease (CVD) has become the number-one cause of death in developing world. This epidemic potential to place a large social and economic burden on countries, where CVD tends strike those their prime working years. Since resources for managing are limited, it is important that interventions be guided by cost-effectiveness results low- middle-income countries. Despite burden, cost-effective strategies exist at population individual levels reducing CVD. Integral all personal...
Suboptimal blood pressure including established nonoptimal has been shown to have significant economic consequences in developed countries. However, no exhaustive study done evaluate its potential costs, globally. We, therefore, set out estimate the global cost of pressure.Estimates for healthcare costs attributed suboptimal those over age 30 were made all World Bank regions. Annual and 10-year estimates using Markov models treating main sequelae: stroke myocardial infarction.Suboptimal...
To estimate individual and household economic impact of cardiovascular disease (CVD) in selected low- middle-income countries (LMIC).Empirical evidence on the microeconomic consequences CVD LMIC is scarce.We surveyed 1,657 recently hospitalized patients (66% male; mean age 55.8 years) from Argentina, China, India, Tanzania to evaluate functional/productivity hospitalization. Respondents were stratified into three income groups. Median out-of-pocket expenditures for treatment over 15 month...
The American College of Cardiology and the Heart Association (ACC/AHA) cholesterol treatment guidelines have wide-scale implications for treating adults without history atherosclerotic cardiovascular disease (ASCVD) with statins.To estimate cost-effectiveness various 10-year ASCVD risk thresholds that could be used in ACC/AHA guidelines.Microsimulation model, including lifetime time horizon, US societal perspective, 3% discount rate costs, health outcomes. In hypothetical individuals from a...
<h3>Importance</h3> Familial hypercholesterolemia (FH) is an underdiagnosed and undertreated genetic disorder that leads to premature morbidity mortality due atherosclerotic cardiovascular disease. affects 1 in 200 250 people around the world of every race ethnicity. The lack general awareness FH among public medical community has resulted only 10% population being diagnosed adequately treated. World Health Organization recognized as a health priority 1998 during consultation meeting Geneva,...
In 2011, the United Nations set key targets to reach by 2025 reduce risk of premature noncommunicable disease death 25% 2025. With cardiovascular being largest contributor global mortality, accounting for nearly half 36 million annual deaths, achieving goal requires that and its factors be aggressively addressed. The Global Cardiovascular Disease Taskforce, comprising World Heart Federation, American Association, College Cardiology Foundation, European Network, Society Cardiology, with...
Cohort Profile : Health and Ageing in Africa: A Longitudinal Study of an INDEPTH Community South Africa (HAALSI)
Hypertension is a major cause of cardiovascular disease and deaths worldwide especially in low- middle-income countries. Despite the availability safe, well-tolerated, cost-effective blood pressure (BP)-lowering therapies, <14% adults with hypertension have BP controlled to systolic/diastolic <140/90 mm Hg. We report new treatment guidelines, developed accordance World Health Organization Handbook for Guideline Development. Overviews reviews evidence were conducted summary tables...
Cardiovascular diseases (CVDs) are the leading cause of mortality globally.Of 20.5 million CVD-related deaths in 2021, approximately 80% occurred low-and middleincome countries.Using data from Global Burden Disease Study, NCD Risk Factor Collaboration, Countdown initiative, WHO Health Observatory, and Expenditure database, we present burden CVDs, associated risk factors, their association with national health expenditures, an index critical policy implementation.The Central Europe, Eastern...
Objectives To determine the prevalence and treatment status of hypertension in South Africa. Design National cross-sectional survey. Setting 13 802 randomly selected Africans, 15 years older, were visited their homes 1998. Methods Trained fieldworkers completed questionnaires on lifestyle chronic diseases, measured blood pressure with an Omron manometer recorded drug utilization. Drugs classified using Anatomical Therapeutic Chemical index. Results The mean systolic for men women was 123...