Honor Bixby
- Obesity, Physical Activity, Diet
- Child Nutrition and Water Access
- Diabetes, Cardiovascular Risks, and Lipoproteins
- Urban and Rural Development Challenges
- Birth, Development, and Health
- Blood Pressure and Hypertension Studies
- Global Public Health Policies and Epidemiology
- Urban Transport and Accessibility
- Land Use and Ecosystem Services
- Nutritional Studies and Diet
- Healthcare cost, quality, practices
- Global Maternal and Child Health
- Cardiovascular Health and Risk Factors
- Chronic Disease Management Strategies
- Urban Agriculture and Sustainability
- Diabetes Management and Research
- Climate Change and Health Impacts
- Sodium Intake and Health
- Health Promotion and Cardiovascular Prevention
- Urban Green Space and Health
- Energy and Environment Impacts
- Health Systems, Economic Evaluations, Quality of Life
- Diabetes Management and Education
- Healthcare Policy and Management
- Lipoproteins and Cardiovascular Health
University of Essex
2023-2025
Imperial College London
2014-2024
McGill University
2021-2023
McGill University Health Centre
2021-2023
City Of Hope National Medical Center
1991
<h2>Summary</h2><h3>Background</h3> One of the global targets for non-communicable diseases is to halt, by 2025, rise in age-standardised adult prevalence diabetes at its 2010 levels. We aimed estimate worldwide trends diabetes, how likely it countries achieve target, and changes prevalence, together with population growth ageing, are affecting number adults diabetes. <h3>Methods</h3> pooled data from population-based studies that had collected on through measurement biomarkers. used a...
Abstract Body-mass index (BMI) has increased steadily in most countries parallel with a rise the proportion of population who live cities 1,2 . This led to widely reported view that urbanization is one important drivers global obesity 3–6 Here we use 2,009 population-based studies, measurements height and weight more than 112 million adults, report national, regional trends mean BMI segregated by place residence (a rural or urban area) from 1985 2017. We show that, contrary dominant...
<h2>Summary</h2><h3>Background</h3> Underweight and obesity are associated with adverse health outcomes throughout the life course. We estimated individual combined prevalence of underweight or thinness obesity, their changes, from 1990 to 2022 for adults school-aged children adolescents in 200 countries territories. <h3>Methods</h3> used data 3663 population-based studies 222 million participants that measured height weight representative samples general population. a Bayesian hierarchical...
BackgroundComparable global data on health and nutrition of school-aged children adolescents are scarce. We aimed to estimate age trajectories time trends in mean height body-mass index (BMI), which measures weight gain beyond what is expected from gain, for adolescents.MethodsFor this pooled analysis, we used a database cardiometabolic risk factors collated by the Non-Communicable Disease Risk Factor Collaboration. applied Bayesian hierarchical model 1985 2019 BMI 1-year groups ages 5–19...
BackgroundThe 2016 Dar Es Salaam Call to Action on Diabetes and Other non-communicable diseases (NCDs) advocates national multi-sectoral NCD strategies action plans based available data information from countries of sub-Saharan Africa beyond. We estimated trends 1980 2014 in age-standardized mean body mass index (BMI) diabetes prevalence these countries, order assess the co-progression assist policy formulation.
Abstract High blood cholesterol is typically considered a feature of wealthy western countries 1,2 . However, dietary and behavioural determinants are changing rapidly throughout the world 3 using lipid-lowering medications at varying rates. These changes can have distinct effects on levels high-density lipoprotein (HDL) non-HDL cholesterol, which different human health 4,5 trends HDL over time not been previously reported in global analysis. Here we pooled 1,127 population-based studies...
Cardiovascular diseases (CVDs) are the leading cause of mortality globally.Of 20.5 million CVD-related deaths in 2021, approximately 80% occurred low-and middleincome countries.Using data from Global Burden Disease Study, NCD Risk Factor Collaboration, Countdown initiative, WHO Health Observatory, and Expenditure database, we present burden CVDs, associated risk factors, their association with national health expenditures, an index critical policy implementation.The Central Europe, Eastern...
Diabetes has been defined on the basis of different biomarkers, including fasting plasma glucose (FPG), 2-h in an oral tolerance test (2hOGTT), and HbA1c. We assessed effect diagnostic definitions both population prevalence diabetes classification previously undiagnosed individuals as having versus not a pooled analysis data from population-based health examination surveys regions.We used 96 that had measured at least two biomarkers for defining diabetes. was using HbA1c (HbA1c ≥6·5% or...
Describing the prevalence and trends of cardiometabolic risk factors that are associated with non-communicable diseases (NCDs) is crucial for monitoring progress, planning prevention, providing evidence to support policy efforts. We aimed analyse transition in body-mass index (BMI), obesity, blood pressure, raised diabetes Americas, between 1980 2014.
Abstract Optimal growth and development in childhood adolescence is crucial for lifelong health well-being 1–6 . Here we used data from 2,325 population-based studies, with measurements of height weight 71 million participants, to report the body-mass index (BMI) children adolescents aged 5–19 years on basis rural urban place residence 200 countries territories 1990 2020. In 1990, residing cities were taller than their counterparts all but a few high-income countries. By 2020, advantage...
Green space has been identified as a modifiable feature of the urban environment and associations with physiological psychological health have reported at local level. This study aims to assess whether these between green are transferable larger scale, English cities unit analysis. We used an ecological, cross-sectional design. classified satellite-based land cover data quantify coverage for 50 largest in England. assessed city risk death from all causes, cardiovascular disease, lung cancer...
Change in the prevalence of raised blood pressure could be due to both shifts entire distribution (representing combined effects public health interventions and secular trends) changes its high-blood-pressure tail successful clinical control hypertensive population). Our aim was quantify contributions these two phenomena worldwide trends pressure. We pooled 1018 population-based studies with measurements on 88.6 million participants from 1985 2016. first calculated mean systolic (SBP),...
Abstract Background Although high-density lipoprotein (HDL) and non-HDL cholesterol have opposite associations with coronary heart disease, multi-country reports of lipid trends only use total (TC). Our aim was to compare in total, HDL the total-to-HDL ratio Asian Western countries. Methods We pooled 458 population-based studies 82.1 million participants 23 estimated changes mean by country, sex age group. Results Since ∼1980, TC increased In Japan South Korea, rise due rising cholesterol,...
Principles of dense, mixed-use environments and pedestrianisation are influential in urban planning practice worldwide. A key outcome espoused by these principles is generating "urban vitality", the continuous use street sidewalk infrastructure throughout day, to promote safety, economic viability attractiveness city neighbourhoods. Vitality hypothesised arise from a nearby mixture primary uses, short blocks, density buildings population diversity age condition surrounding buildings. To...
The consumption of packaged water in Ghana has grown significantly recent years. By 2017, “sachet water”—machine-sealed 500ml plastic bags drinking water—was consumed by 33% Ghanaian households. Reliance on sachet previously been associated with the urban poor, yet evidence suggests a customer base which crosses socioeconomic lines. Here, we conduct repeated cross-sectional analysis three nationally representative datasets to examine changing demography consumers between 2010 and 2017. Our...
Universal access to safe drinking water is essential population health and well-being, as recognized in the Sustainable Development Goals (SDG). To develop targeted policies which improve urban improved ensure equity, there need understand spatial heterogeneity sources factors underlying these patterns. Using Shannon Entropy Index of Concentration at Extremes enumeration area level, we analyzed census data examine neighborhood income Greater Accra Metropolitan Area (GAMA), largest...
Identifying urban deprived areas, including slums, can facilitate more targeted planning and development policies in cities to reduce socio-economic health inequities, but methods identify them are often ad-hoc, resource intensive, cannot keep pace with rapidly urbanizing communities.
The pressure to contain health expenditures is unprecedented. In England a flattening of the budget but increasing demand led National Health Service (NHS) seek reductions in 17 percent over four years. spending cuts were be achieved through improvements service quality and efficiency, including reducing use ineffective, overused, or inappropriate procedures. However, NHS left it local commissioning (or funding) organizations, known as primary care trusts, determine what steps take reduce...
Countries in sub-Saharan Africa suffer the highest rates of child mortality worldwide. Urban areas tend to have lower than rural areas, but these comparisons likely mask large within-city inequalities. We aimed estimate under-five (U5M) at neighbourhood level for Ghana's Greater Accra Metropolitan Area (GAMA) and measure extent intraurban accessed data on >700 000 women aged 25-49 years living GAMA using most recent Ghana census (2010). summarised counts births deaths by five-year age group...
Acute myocardial infarction (AMI) poses a serious disease burden in China, but studies on small-area characteristics of AMI incidence are lacking. We therefore examined temporal trends and geographic variations at the township level Beijing. In this cross-sectional analysis, 259,830 events during 2007–2018 from Beijing Cardiovascular Disease Surveillance System were included. estimated for 307 consistent townships consecutive 3-year periods with Bayesian spatial model. From 2007 to 2018,...
In 25 patients with chronic renal failure undergoing hemodialysis the level of epidermal growth factor (EGF) was significantly increased in plasma (61 ± 10 vs. 36 12 pM 23 age-matched controls; p < 0.0001) and serum (189 51 138 69 pM, 0.006) slightly platelets (391 134 308 87 aM/106 0.0582). those 15 who produced urine, EGF absent or close to low limit sensitivity method (17 pM). Thus, kidneys are not delivering blood but their role removal is possible. Urinary virtually disappears severe failure.