Lap Ah Tse

ORCID: 0000-0003-0355-6218
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About
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Research Areas
  • Air Quality and Health Impacts
  • Occupational and environmental lung diseases
  • Nutritional Studies and Diet
  • Nutrition, Genetics, and Disease
  • Climate Change and Health Impacts
  • Cancer Risks and Factors
  • Energy and Environment Impacts
  • Sleep and related disorders
  • Sleep and Work-Related Fatigue
  • Obesity, Physical Activity, Diet
  • Global Cancer Incidence and Screening
  • Noise Effects and Management
  • Global Health Care Issues
  • Occupational exposure and asthma
  • Phytoestrogen effects and research
  • Chronic Obstructive Pulmonary Disease (COPD) Research
  • Effects and risks of endocrine disrupting chemicals
  • Carcinogens and Genotoxicity Assessment
  • Circadian rhythm and melatonin
  • Head and Neck Cancer Studies
  • COVID-19 and Mental Health
  • Occupational Health and Safety Research
  • Diabetes, Cardiovascular Risks, and Lipoproteins
  • Health disparities and outcomes
  • Cardiovascular Health and Risk Factors

Chinese University of Hong Kong
2016-2025

Hong Kong Jockey Club
2016-2025

Chinese University of Hong Kong, Shenzhen
2014-2025

Prince of Wales Hospital
2006-2023

Aarhus University
2023

City University of Hong Kong, Shenzhen Research Institute
2021

University of Hong Kong
2021

Primary Health Care
2020

Nanjing Medical University
2017

Deichmann (Germany)
2016

Evidence concerning the acute health effects of air pollution caused by fine particulate matter (PM2.5) in developing countries is quite limited.To evaluate short-term associations between PM2.5 and daily cause-specific mortality China.A nationwide time-series analysis was performed 272 representative Chinese cities from 2013 to 2015. Two-stage Bayesian hierarchical models were applied estimate regional- national-average concentrations mortality. City-specific estimated using overdispersed...

10.1164/rccm.201609-1862oc article EN American Journal of Respiratory and Critical Care Medicine 2017-03-01

Abstract We examined the correlation between lung cancer incidence/mortality and country-specific socioeconomic development, evaluated its most recent global trends. retrieved age-standardized incidence rates from GLOBOCAN database, temporal patterns were assessed databases. employed simple linear regression analysis to evaluate their correlations with Human Development Index (HDI) Gross Domestic Product (GDP) per capita. The average annual percent changes (AAPC) of trends join-point...

10.1038/s41598-017-14513-7 article EN cc-by Scientific Reports 2017-10-24

To investigate the association of estimated total daily sleep duration and daytime nap with deaths major cardiovascular events.We durations naps based on amount time in bed self-reported napping examined associations between them composite outcome events 116 632 participants from seven regions. After a median follow-up 7.8 years, we recorded 4381 4365 events. It showed both shorter (≤6 h/day) longer (>8 were associated an increased risk when adjusted for age sex. adjustment demographic...

10.1093/eurheartj/ehy695 article EN European Heart Journal 2018-10-06

There is limited information on the relationship between risk of cardiovascular disease and joint effects sleep quality duration, especially from large, prospective, cohort studies. This study to prospectively investigate duration development coronary heart disease.This examined 60,586 adults aged 40 years or older. A self-administered questionnaire was used collect as well a wide range potential confounders. Events were self-reported in subsequent medical examinations. Two types Sleep Score...

10.5664/jcsm.6894 article EN Journal of Clinical Sleep Medicine 2018-01-12

Non-communicable diseases (NCDs) are the leading cause of death globally. In 2014, United Nations committed to reducing premature mortality from NCDs, including by burden healthcare costs. Since Prospective Urban and Rural Epidemiology (PURE) Study has been collecting health expenditure data households with NCDs in 18 countries.Using PURE Study, we estimated risk catastrophic spending impoverishment among at least one person (cardiovascular disease, diabetes, kidney cancer respiratory...

10.1136/bmjgh-2019-002040 article EN cc-by BMJ Global Health 2020-02-01

Most studies of long-term exposure to outdoor fine particulate matter (PM2·5) and cardiovascular disease are from high-income countries with relatively low PM2·5 concentrations. It is unclear whether risks similar in low-income middle-income (LMICs) how contributes the global burden disease. In our analysis Prospective Urban Rural Epidemiology (PURE) study, we aimed investigate association between concentrations a large cohort adults 21 high-income, middle-income, countries.In this...

10.1016/s2542-5196(20)30103-0 article EN cc-by-nc-nd The Lancet Planetary Health 2020-06-01

Abstract Aims To examine the incidence of cardiovascular disease (CVD) and mortality in China key subpopulations, to estimate population-level risks attributable 12 common modifiable risk factors for each outcome. Methods results In this prospective cohort 47 262 middle-aged participants from 115 urban rural communities provinces China, it was examined how CVD rates varied by sex, urban-rural area, region. without prior CVD, population-attributable fractions (PAFs) death related were...

10.1093/eurheartj/ehac268 article EN European Heart Journal 2022-05-11

Metabolic syndrome (MetS) is a common metabolic disorder that results from the increasing prevalence of obesity, which has been an concern in recent years. Previous evidence indicated MetS was associated with mortality; however, different definitions were used. In 2005, National Cholesterol Education Program (NCEP) Adult Treatment Panel (ATP) III updated definition MetS, since widely adopted. Therefore, it necessary to conduct novel study among other populations and countries larger sample...

10.2196/44073 article EN cc-by JMIR Public Health and Surveillance 2023-09-05

Many epidemiological studies have linked daily counts of hospital admissions to particulate matter (PM) with an aerodynamic diameter ≤ 10 μm (PM10) and 2.5 (PM2.5), but relatively few investigated the relationship coarse PM (PMc; 2.5-10 diameter).We conducted this study estimate health effects PMc on emergency for respiratory diseases in Hong Kong after controlling PM2.5 gaseous pollutants.We a time-series analysis associations between from January 2000 December 2005 concentrations. We...

10.1289/ehp.1104002 article EN public-domain Environmental Health Perspectives 2012-01-20

Background:Previous reports suggested that female breast cancer is associated with earlier ages at onset among Asian than Western populations. However, most studies utilized cross-sectional analyses may be confounded by calendar-period and/or birth cohort effects. We, therefore, considered a longitudinal (forward-looking) approach adjusted for changes and conditioned upon cohort.

10.1093/jnci/djv107 article EN public-domain JNCI Journal of the National Cancer Institute 2015-04-13

Background: Household air pollution (HAP) from solid fuel use for cooking affects 2.5 billion individuals globally and may contribute substantially to disease burden. However, few prospective studies have assessed the impact of HAP on mortality cardiorespiratory disease. Objectives: Our goal was evaluate associations between mortality, cardiovascular (CVD), respiratory in urban rural epidemiology (PURE) study. Methods: We studied 91,350 adults 35–70 y age 467 communities 11 countries...

10.1289/ehp3915 article EN public-domain Environmental Health Perspectives 2019-05-01

BackgroundApproximately 2·8 billion people are exposed to household air pollution from cooking with polluting fuels. Few monitoring studies have systematically measured health-damaging pollutant (ie, fine particulate matter [PM2·5] and black carbon) concentrations a wide range of fuels across diverse populations. This multinational study aimed assess the magnitude kitchen personal exposures PM2·5 carbon in rural communities environments.MethodsAs part Prospective Urban Rural Epidemiological...

10.1016/s2542-5196(20)30197-2 article EN cc-by The Lancet Planetary Health 2020-10-01

<b><i>Objective:</i></b> Obesity-related disease risks may vary depending on whether the subject has metabolically healthy obesity (MHO) or unhealthy (MUO). At least 5 definitions/criteria of and metabolic disorders have been documented in literature, yielding uncertainties a reliable international comparison phenotype prevalence. This report aims to compare differences MHO MUO prevalence according most frequently used definitions.<b><i>...

10.1159/000495852 article EN cc-by-nc-nd Obesity Facts 2019-01-01

Background The predictive value of adiposity indices and the newly developed index for cardiometabolic risk factors cardiovascular diseases ( CVD s) remains unclear in Chinese population. This study aimed to compare A Body Shape Index with other 5 conventional obesity‐related anthropometric (body mass index, waist circumference, hip waist‐to‐hip ratio, waist‐to‐height ratio) Methods Results total 44 048 participants were derived from baseline data PURE ‐China (Prospective Urban Rural...

10.1161/jaha.118.010870 article EN cc-by-nc-nd Journal of the American Heart Association 2019-08-09

Although socioeconomic inequality in cardiovascular health has long been a public focus, the differences cardiovascular-disease burden and mortality between people with different statuses yet to be adequately addressed. We aimed assess effects of status, measured via three socioeconomic-status indicators (ie, education, occupation, household wealth composite disparity index, on incidence, mortality, admission hospital) China.For this analysis, we used data from Prospective Urban Rural...

10.1016/s2468-2667(23)00244-x article EN cc-by-nc-nd The Lancet Public Health 2023-11-22

Abstract Background An inverse relationship between physical activity (PA) and depression among adolescents has been reported in developed communities without consideration of sedentary behaviors (SB, including sitting for course study, viewing TV, sleeping). We explored the association recreational PA time (hr/wk) after adjustment with SB other possible confounders Chinese adolescents. Methods A population-based cross-sectional study was conducted Nanjing municipality China 2004 using a...

10.1186/1471-2458-9-148 article EN cc-by BMC Public Health 2009-05-20
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