<b><i>Objective:</i></b> Obesity-related disease risks may vary depending on whether the subject has metabolically healthy obesity (MHO) or unhealthy (MUO). At least 5 definitions/criteria of and metabolic disorders have been documented in literature, yielding uncertainties a reliable international comparison phenotype prevalence. This report aims to compare differences MHO MUO prevalence according most frequently used definitions.<b><i>...

Objectives. To understand declines in chronic disability prevalence the U.S. elderly population, we examined cohort changes active life expectancy, a health measure relating population and longevity dynamics.

The CHA2DS2-VASc score and left atrial epicardial adipose tissue (LA-EAT) volume have been identified as potential risk factors for fibrillation (AF) recurrence after ablation. However, there is currently a lack of research specifically examining the interaction between these two AF factors. This study aims to evaluate predictive combining LA-EAT in predicting patients with who undergo encompassed cohort 507 underwent ablation finally. Follow-up assessments were conducted 1, 3, 6, 12 months...

We assessed the effect of asymptomatic carotid atherosclerosis (CAS) on development cardiovascular diseases (CVDs) in a community-based population aged ≥55 years China. A total 1376 residents underwent CAS assessment by ultrasonography July 2009. New CVD events, including stroke and coronary heart were collected at follow-up survey end 2014. After adjusting for baseline demographic characteristics traditional risk factors, patients with minimal (mean common artery intima–media thickness...

We explored the associations between lipoprotein-associated phospholipase A2 (Lp-PLA2) level and carotid atherosclerosis with all phenotypes cardiovascular disease (CVD) events in Chinese older adults. A total of 1257 adults aged ≥55 years who were free CVD enrolled this cohort study. Lipoprotein-associated was evaluated 3 categories: Lp-PLA2 < 175, 175≤ 223, ≥ 223 ng/mL. The highest independently associated common artery intima-media thickening (≥1.0 mm; odds ratio [OR]: 1.60, 95%...

Background: The association between homocysteine and cardiovascular diseases (CVD) all-cause death was inconclusive. A community-based prospective cohort study carried out in Beijing to evaluate this elderly population for more effective clinical prediction primary prevention of CVD. Patients Methods: Participants were randomly selected from Beijing, China. Questionnaire survey, physical examinations, laboratory tests collect baseline information investigate characteristics. Each participant...

The plasma and tissue pharmacokinetics of marbofloxacin in chickens experimentally infected with Mycoplasma gallisepticum Escherichia coli were studied. Marbofloxacin was given to 66 by oral administration at a dosage 5 mg/kg b.w., once day for three days. Plasma, brain, kidney, liver, lung, muscle trachea collected concentrations analyzed high performance liquid chromatography method. In the chickens, maximal plasma, 1.84, 1.33, 7.35, 5.61, 3.12, 2.98, 4.51 g/mL (g); elimination half‐lives...

We investigated the association between kidney dysfunction and carotid atherosclerosis in community-based older adults. This study consisted of 1257 participants, aged 55 years free cardiovascular disease. Kidney was classified as mild, moderate, severe (estimated glomerular filtration rate, 45-59, 30-44, &lt;30 mL/min/1.73 m 2 , respectively). found that mean common artery intima–media thickness (CCA-IMT) progressively increased with decrement function ( P &lt; .001). Even mild...

To investigate the frailty, as estimated by accumulated health deficits, in association with symptomatic carotid atherosclerosis and relation to five-year cardiovascular (CVD) outcomes.This is a prospective cohort study. Secondary analysis of data from Beijing Longitudinal Study on Aging. Community-dwelling people aged 55+ years (n = 1257) have been followed between 2009 2014, having ultrasonography examinations no CVD events at baseline. Frailty was quantified using deficit...

Objective To explore the association of depression, as well untreated hypertension or diabetes with all-cause death in community-based postmenopausal women Beijing.Methods A cohort 863 no history cardiovascular heart disease (CHD), stroke, cancer, dementia was investigated on 20 July–28 September 2009 at baseline. Depression diagnosed using 30-item Center for Epidemiologic Studies (CES-D) scale CES-D ≥ 11. Meanwhile, data health behavior, physical comorbidity, and social support baseline...

Previous studies on the importance of metabolic syndrome (MS) as a cardiovascular risk factor had not focused older Chinese adults. The present study analyzed association MS with carotid atherosclerosis and events in adults.Data representative cohort 5-year follow-up were used. Community-dwelling people (n=1257) aged ≥55 years without disease (CVD) at baseline followed up from 2009 to 2014. was defined based Diabetes Society criteria under Medical Association. Multiple regression analyses...

Increased homocysteine levels are associated with the risk of cardiovascular disease (CVD) and death. However, their prevention has not been effective in decreasing CVD risk. This study investigated individual combined associations hyperhomocysteinemia hypertension incident events all-cause death Chinese elderly population without a history CVD.This prospective was conducted among 1,257 participants (mean age: 69 years). A questionnaire survey, physical examinations, laboratory tests were to...

Abstract Background Frailty can be operationalized based on the accumulation of deficits using a frailty index (FI) and is associated with an increased risk adverse health outcomes. Here, we aim to compare validity FI from laboratory data that common clinical for prediction mortality in adults aged 55 + years, also examine whether combined could improve identification years at death. Methods Data this analysis were obtained Beijing Longitudinal Study Aging involved 1,257 community-dwelling...

The purpose of this study was to investigate the curative effect 1α-hydroxyvitamin D3 on benign paroxysmal positional vertigo (BPPV). Fifty BPPV patients diagnosed in ENT Department Anzhen Hospital from October 2015 December 2016 were randomly selected as treatment group, and treated with 0.25 µg once per day, addition routine diagnosis treatment. Moreover, 50 same period control received detection results bone mineral density (BMD) t-value, vitamin metabolic markers before after compared,...

To evaluate the association between kidney dysfunction and cardiovascular disease (CVD) events in a middle-aged elderly population China.In July 2009, baseline survey of health status was performed adults aged 55 years older from Beijing, China. Occurrence CVD mortality subjects free at recorded 5-year follow-up period until December 2014. The mild (eGFRCKD-EPI 45 - 59 mL/min/1.73m2) moderate to severe < with adverse outcomes were analyzed Cox regression analysis.A total 1,257 included final...

A stroke prediction model based on the Prediction for Atherosclerotic Cardiovascular Disease Risk in China (China-PAR) project was developed. We compared its predictive ability with revised Framingham Stroke Score (R-FSRS) 5-year incidence a community cohort of Chinese adults, namely Beijing Longitudinal Study Aging (BLSA). Calibration, discrimination, and recalibration were used to compare between two models. Category-less net reclassification improvement (NRI) integrated discrimination...

Abstract Background ApoE gene polymorphism and serum total homocysteine (tHcy) has been reportedly associated with cognition. In this study, we assessed the association of combined tHcy cognition in Chinese elder adults. Methods A cross- sectional study was carried out by recruiting 1458 community-dwelling people aged 55+ above Beijing 2009. All participants were interviewed using a standard questionnaire underwent physical examination. The mini-mental scale examination (MMSE) score used...

Abstract The associations of blood pressure components with cardiovascular risks and death remain unclear, the definition wide pulse (PP) is still controversial. Using data from 1257 participants without a history disease, who were followed for 4.84 years, we performed multivariable Cox regression analyses to assess how systolic (SBP), diastolic (DBP), PP contribute events all‐cause death. Among all participants, SBP significantly associated (all p &lt; .05). DBP was not risk death; rather,...

To evaluate the efficacy and safety of subthreshold micropulse laser (SMPL) combined with ranibizumab in treating diabetic macular edema (DME).

Since the chronic kidney disease (CKD) and end-stage renal (ESRD) can cause serious burden consume huge amounts of health resources to human life, research on CKD received increasing attention. For particularity elderly, whether current definition, stages function assessment should be distinguished from adults has been controversial. We conducted a comprehensive review these issues. Furthermore, studies epidemiologic status, trends, characteristics for elderly were summarized, possible...

The prevalence and risk factors of intracranial atherosclerotic stenosis (ICAS) located in the anterior circulation (AC) posterior (PC) has been scarcely noted general population. We aimed to determine ICAS factor profile AC PC a representative Data were from China Hypertension Survey Beijing. In total, 4800 people aged 35 years or older enrolled this subsurvey for ICAS, 3954 participants eligible analysis. was assessed by transcranial Doppler. much greater than that (11.9% vs. 4.2%),...

A 32-year-old women had a first baby. Both parents are healthy, and both them have not genetic disease history. In the following pregnancy, trimester ultrasound second biochemical screening were normal. However, at 30 weeks 39 ultrasonography showed respectively 8 mm 10 diameter thick middle of fetal ventricular septal on four-chamber view, other structure heart was no abnormal. Color Doppler imaging abnormal flow signals obviously. After birth baby referred with cardiac examination one...