A5085654884- Cancer-related molecular mechanisms research
- Blood Pressure and Hypertension Studies
- Neurological Disease Mechanisms and Treatments
- Tuberculosis Research and Epidemiology
- Cardiac Fibrosis and Remodeling
- MicroRNA in disease regulation
- Mycobacterium research and diagnosis
- Circular RNAs in diseases
- Cardiovascular Health and Risk Factors
- Health and Well-being Studies
- Lipoproteins and Cardiovascular Health
- Bone health and treatments
- Dementia and Cognitive Impairment Research
- Nutritional Studies and Diet
- Folate and B Vitamins Research
- Plant Water Relations and Carbon Dynamics
- Health disparities and outcomes
- Irrigation Practices and Water Management
- Signaling Pathways in Disease
- Acute Myocardial Infarction Research
- Cardiac Imaging and Diagnostics
- Multiple Myeloma Research and Treatments
- Monoclonal and Polyclonal Antibodies Research
- Renin-Angiotensin System Studies
- Sodium Intake and Health
Nanjing Medical University
2020-2024
Jiangsu Province Hospital
2020-2024
Capital Medical University
2014-2024
Beijing Chest Hospital
2017-2024
Kunming Medical University
2016-2023
Soochow University
2021-2023
First Affiliated Hospital of Kunming Medical University
2016-2023
Second Affiliated Hospital of Soochow University
2021-2023
Inner Mongolia Electric Power Survey & Design Institute (China)
2023
Chinese Academy of Medical Sciences & Peking Union Medical College
2016-2022
Epidemiologic studies on mild cognitive impairment (MCI) are limited in China.Using a multistage cluster sampling design, total of 10,276 community residents (6096 urban, 4180 rural) aged 65 years or older were evaluated and diagnosed with normal cognition, MCI, dementia. MCI was further categorized by imaging into caused prodromal Alzheimer's disease (MCI-A), resulting from cerebrovascular (MCI-CVD), vascular risk factors (MCI-VRF), other diseases (MCI-O).The prevalences overall MCI-A,...
Investigating the molecular mechanisms of myocardial infarction (MI) and subsequent heart failure have gained considerable attention worldwide. Long noncoding RNA (lncRNA) metastasis-associated lung adenocarcinoma transcript 1 (MALAT1) has been previously demonstrated to regulate proliferation metastasis several tumors. However, little is known about effects MALAT1 in MI regulating cell date after MI. In our study, first, it was shown that expression levels were increased samples compared...
To investigate community synergy of lactic acid bacteria (LAB) and cleaner fermentation oat silage, silages were prepared with or without (control) commercial LAB inoculants LI1 (containing Lactiplantibacillus plantarum, Lentilactobacillus buchneri, Lacticaseibacillus paracasei, Pediococcus acidilactici) LI2 plantarum buchneri). The microbial community, synergy, analyzed at 1, 3, 6, 15, 35, 90 days ensiling. inoculant improved quality, significantly (P < 0.05) lower pH, ammonia nitrogen...
Abstract Introduction The status of dementia diagnosis and treatment neurology outpatients in general hospitals China remains unclear. Methods From at 36 randomly selected hospitals, we first collected baseline data concerning the number doctors, memory clinics, patients diagnosed with dementia. In stage 2, intervened based on drawbacks discovered 1, implementing a initiative program. 3, reinvestigated to determine effects intervention. Results After intervention, all had established clinics...
Packing density has a significant influence on the outcome of ensiling forage. In this study, we aim to investigate effect packing properties, microbiome, and in vitro digestibility barley silages. Barley was ensiled polyethylene drum silos (30 L) with respective densities 600, 650, 700, 750 kg/m3 fresh matter (FM), stored for 60 days. The bacterial communities, fermentation quality, were analyzed. Fresh had low count lactic acid bacteria (LAB, 104 cfu/g FM), Lactobacillus nearly...
Abstract Background Metabolic syndrome (MetS) is characterized by a cluster of signs metabolic disturbance and has caused huge burden on the health system. The study aims to explore prevalence characteristics MetS defined different criteria in Chinese population. Methods Using data China Hypertension Survey (CHS), nationally representative cross-sectional from October 2012 December 2015, total 28,717 participants aged 35 years above were included analysis. definitions International Diabetes...
There is insufficient evidence to show that the guidelines' recommendations of physical activity (PA) are associated with long-term benefits in individuals hypertension.This prospective cohort study included UK Biobank participants hypertension. Time spent on vigorous-intensity PA (VPA), moderate-intensity (MPA), and light-intensity (LPA) measured by wrist-worn accelerometer were extracted. The primary outcomes major adverse cardiovascular events (including death, stroke, myocardial...
Aim: To systematically classify the profile of RNA m6A modification landscape neonatal heart regeneration. Materials and Methods: Cardiomyocyte proliferation markers were detected via immunostaining. The expression regulators was using quantitative real-time PCR (qPCR) Western blotting. Genome-wide profiling methylation-modified transcripts conducted with immunoprecipitation sequencing (m6A-RIP-seq) (RNA-seq). Gene Expression Omnibus database (GEO) dataset used to verify hub genes. Results:...
Abstract Alamandine (Ala) is the newest identified peptide of renin-angiotensin system and has protective effect on myocyte hypertrophy. However, it still unclear whether Ala can alleviate heart failure (HF). The aim this study was to explore effects HF related cardiac fibrosis, probe mechanism. model induced by myocardial infarction (MI) in mice. Four weeks after MI, administrated intraperitoneal injection for two weeks. significantly improved dysfunction MI mice vivo. fibrosis biomarkers...