Na Na

ORCID: 0000-0002-9394-8209
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About
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Research Areas
  • Advanced biosensing and bioanalysis techniques
  • Advanced Chemical Sensor Technologies
  • Ruminant Nutrition and Digestive Physiology
  • Melanoma and MAPK Pathways
  • Gas Sensing Nanomaterials and Sensors
  • Nanocluster Synthesis and Applications
  • Analytical Chemistry and Chromatography
  • Probiotics and Fermented Foods
  • Hemoglobin structure and function
  • Mass Spectrometry Techniques and Applications
  • Biosensors and Analytical Detection
  • Food composition and properties
  • Analytical Chemistry and Sensors
  • Nuclear and radioactivity studies
  • Neonatal Health and Biochemistry
  • Meat and Animal Product Quality
  • Colorectal Cancer Treatments and Studies
  • Microfluidic and Capillary Electrophoresis Applications
  • Gold and Silver Nanoparticles Synthesis and Applications
  • RNA Interference and Gene Delivery
  • Animal Nutrition and Physiology
  • Radioactive contamination and transfer
  • Adipose Tissue and Metabolism
  • MicroRNA in disease regulation
  • Erythrocyte Function and Pathophysiology

First Affiliated Hospital of GuangXi Medical University
2025

Guangxi Medical University
2025

Scripps Research Institute
2023-2025

Institute of Grassland Research
2025

Chinese Academy of Agricultural Sciences
2025

Inner Mongolia Academy of Agricultural & Animal Husbandry Sciences
2021-2024

Harbin Medical University
2011-2024

Second Affiliated Hospital of Harbin Medical University
2011-2024

Beijing Normal University
2014-2024

Affiliated Hospital of Qingdao University
2014-2024

Abstract Trace amounts of explosives on solid surfaces were detected by mass spectrometry at ambient conditions with a new technique termed dielectric barrier discharge ionization (DBDI). By the needle–plate mode, plasma energetic electrons was generated, which could launch desorption and from surfaces. Hexahydro‐1,3,5‐trinitro‐1,3,5‐triazine (RDX), 2,4,6‐trinitrotoluene (TNT), pentaerythritol tetranitrate (PETN) desorbed directly explosives‐contaminated surface DBDI, forming typical anions...

10.1002/jms.1243 article EN Journal of Mass Spectrometry 2007-07-06

This paper describes a visual sensor array for pattern recognition analysis of proteins based on two different optical signal changes: colorimetric and fluorometric, by using types novel blue-emitting collagen protected gold nanoclusters macerozyme R-10 with lower synthetic demands. Eight have been well-discriminated this array, protein mixtures after one-dimensional polyacrylamide gel electrophoresis also could be well-discriminated. The possible mechanism was illustrated validated...

10.1021/ac502643s article EN Analytical Chemistry 2014-11-06

Mutations at multiple sites in MEK1 occur cancer, suggesting that their mechanisms of activation might be different. We analyzed 17 tumor-associated mutants and found they drove ERK signaling autonomously or a RAS/RAF-dependent manner. The latter are sensitive to feedback inhibition RAF, which limits functional output, often cooccur with RAS RAF mutations. They act as amplifiers signaling. In contrast, another class deletes hitherto unrecognized negative regulatory segment MEK1, is RAF-...

10.1158/2159-8290.cd-17-1452 article EN Cancer Discovery 2018-02-27

An optical sensor array based on chemiluminescent images from spots of nanomaterials has been employed to recognize odorous samples. The distinctive obtained the permit identification a wide range analytes, even homologous compounds.

10.1021/ja063632f article EN Journal of the American Chemical Society 2006-10-21

Background: Genistein, one of the major isoflavones, has received great attention as a phytoestrogen and potential cancer chemoprevention agent. However, dissolution bioavailability genistein from solid oral preparations is low due to its poor water solubility. Methods: In order improve genistein, nanoparticles were prepared by nanoprecipitation technique using Eudragit ® E100 carriers an optimized formulation mass ratio (genistein:Eudragit E100, 1:10). The mean particle size was...

10.2147/ijn.s24185 article EN cc-by-nc International Journal of Nanomedicine 2011-10-01

Abstract Nanogap antennas are plasmonic nanostructures with a strong electromagnetic field generated at the gap region of two neighboring particles owing to coupling collective surface plasmon resonance. They have great potential for improving optical properties fluorophores. Herein, nanogap constructed using an aqueous solution‐based method overcome defects weak fluorescence and photobleaching associated traditional organic dyes, highly sensitive antenna‐based sensing strategy is presented...

10.1002/smll.202000460 article EN Small 2020-04-20

The present study was aimed at investigating the bacterial community in lactic acid bacteria (LAB) suspensions prepared from whole-plant corn silage (LAB suspension-CS) and Elymus sibiricus suspension-ES) succession of silages inoculated with LAB suspension-CS or suspension-ES during initial aerobic phase, intense fermentation stable phase. were cultured sterile Man, Rogosa, Sharpe broth 37°C for 24 h used as inoculants ensiling. chopped treated distilled water (CK), (CSL), (ESL) then...

10.3389/fmicb.2021.655095 article EN cc-by Frontiers in Microbiology 2021-03-26

To investigate community synergy of lactic acid bacteria (LAB) and cleaner fermentation oat silage, silages were prepared with or without (control) commercial LAB inoculants LI1 (containing Lactiplantibacillus plantarum, Lentilactobacillus buchneri, Lacticaseibacillus paracasei, Pediococcus acidilactici) LI2 plantarum buchneri). The microbial community, synergy, analyzed at 1, 3, 6, 15, 35, 90 days ensiling. inoculant improved quality, significantly (P < 0.05) lower pH, ammonia nitrogen...

10.1128/spectrum.00705-23 article EN cc-by Microbiology Spectrum 2023-05-11

Cardiovascular diseases (CVDs) have emerged as a predominant threat to human health, surpassing the incidence and mortality rates of neoplastic diseases. Extracellular vesicles (EVs) serve vital mediators in intercellular communication material exchange. Endothelial progenitor cells (EPCs), recognized precursors vascular endothelial (ECs), garnered considerable attention recent years due potential therapeutic value their derived extracellular (EPC-EVs) context CVDs. This comprehensive review...

10.1186/s13578-024-01255-z article EN cc-by Cell & Bioscience 2024-06-05

A cross-reactive chemiluminescence (CL) sensor array based on catalytic nanomaterials was constructed for the discrimination and identification of flavors in cigarettes. total 21 nanomaterials, including metal oxides, oxides deposited carbon nanotubes (CNTs), gold nanoparticles carbonate, have been carefully selected as sensing elements array. Each flavor gives its unique CL pattern from array, which is able to be employed flavors. Hierarchical cluster analysis (HCA) linear discriminant...

10.1021/ac801733k article EN Analytical Chemistry 2009-01-02

Four electron-donor-substituted aggregation-induced emission (AIE) compounds, N,N'-bis(4-methoxylsalicylidene)-p-phenylenediamine (BSPD-OMe), N,N'-bis(4-methylsalicylidene)-p-phenylenediamine (BSPD-Me), N,N'-bis(salicylidene)-p-phenylenediamine (BSPD), and N,N'-bis(4-hydroxylsalicylidene)-p-phenylenediamine (BSPD-OH), are designed synthesized. They all found to exhibit controlled self-assembly behaviors good thermal properties. By changing the terminal electron-donor groups, they...

10.1021/la404436v article EN Langmuir 2014-02-18

Packing density has a significant influence on the outcome of ensiling forage. In this study, we aim to investigate effect packing properties, microbiome, and in vitro digestibility barley silages. Barley was ensiled polyethylene drum silos (30 L) with respective densities 600, 650, 700, 750 kg/m3 fresh matter (FM), stored for 60 days. The bacterial communities, fermentation quality, were analyzed. Fresh had low count lactic acid bacteria (LAB, 104 cfu/g FM), Lactobacillus nearly...

10.3390/agriculture11070672 article EN cc-by Agriculture 2021-07-15

&lt;p&gt;With the rapid development of DNA nanotechnology, emergence fluorescent nanostructures (FDNs) has enlarged biological applications. FDNs have great advantages precise localization and real-time tracing in bioimaging. In this review, recent biomedical developments been reviewed, including design FDNs, corresponding applications on biomarker sensing, bioimaging, cancer diagnosis therapy. Firstly, DNA-based nanomaterials were briefly introduced. Simultaneously, to make a better...

10.59717/j.xinn-mater.2024.100064 article EN cc-by The Innovation Materials 2024-01-01

Thymus mongolicus (Lamiaceae) is a plant commonly found throughout China, in which it widely used chemical products for daily use, traditional medicinal preparations, ecological management, and cooking. In this study, we have assembled annotated the first time entire mitochondrial genome (mitogenome) of T. mongolicus. The composed monocyclic structure, with an overall size 450,543 base pairs (bp) GC composition 45.63%. It contains 32 unique protein-encoding genes. repetitive sequences...

10.3390/biom15030343 article EN cc-by Biomolecules 2025-02-27
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