- Anesthesia and Pain Management
- Coronary Interventions and Diagnostics
- Lipoproteins and Cardiovascular Health
- Anesthesia and Sedative Agents
- Blood Pressure and Hypertension Studies
- Nutritional Studies and Diet
- Atrial Fibrillation Management and Outcomes
- Acute Myocardial Infarction Research
- Health Systems, Economic Evaluations, Quality of Life
- Cardiac Imaging and Diagnostics
- Antiplatelet Therapy and Cardiovascular Diseases
- Coronary Artery Anomalies
- Anesthesia and Neurotoxicity Research
- Diabetes, Cardiovascular Risks, and Lipoproteins
- Pain Management and Opioid Use
- Heart Failure Treatment and Management
- Acute Ischemic Stroke Management
- Pediatric Pain Management Techniques
- Spine and Intervertebral Disc Pathology
- Cardiac electrophysiology and arrhythmias
- Cardiac Arrhythmias and Treatments
- Obesity, Physical Activity, Diet
- Sodium Intake and Health
- Nausea and vomiting management
- Pharmaceutical Economics and Policy
Ankara University
2016-2025
Eskişehir Osmangazi University
2006-2024
İstanbul Eğitim ve Araştırma Hastanesi
2018
Population Health Research Institute
2013
Hamilton General Hospital
2013
Eskişehir Osmangazi Üniversitesi Tıp Fakültesi Hastanesi
2011
University of Minnesota
2002-2003
Twin Cities Orthopedics
2002
Louisiana State University
1999
Mount Sinai Medical Center
1999
Addendum I. SCORE charts with high-density lipoprotein-cholesterol II.Practical approach to reach low-density goal III.Inhibitors and inducers
The optimal range of sodium intake for cardiovascular health is controversial.We obtained morning fasting urine samples from 101,945 persons in 17 countries and estimated 24-hour potassium excretion (used as a surrogate intake). We examined the association between urinary composite outcome death major events.The mean was 4.93 g per day 2.12 day, respectively. With follow-up 3.7 years, occurred 3317 participants (3.3%). As compared with an 4.00 to 5.99 (reference range), higher (≥ 7.00 day)...
Socioeconomic status is associated with differences in risk factors for cardiovascular disease incidence and outcomes, including mortality. However, it unclear whether the associations between common measures of socioeconomic status-wealth education-differ among high-income, middle-income, low-income countries, and, if so, why these exist. We explored association education household wealth mortality to assess which marker stronger predictor examined any by parallel factor levels or...
2][3] Smoking cessation is associ-ated with a lower risk of death and myocardial infarction, high-quality diets 1,4 regular exercise are associated or recurrent cardiovascular disease events after infarction. 1-3Thus, avoidance smoking its cessation, improving diet quality, increasing physical ac-tivity level recommended for secondary prevention disease.
BackgroundThe triglyceride glucose (TyG) index is an easily accessible surrogate marker of insulin resistance, important pathway in the development type 2 diabetes and cardiovascular diseases. However, association TyG with diseases mortality has mainly been investigated Asia, few data available from other regions world. We assessed resistance (as determined by index) individuals five continents at different levels economic development, living urban or rural areas. also examined whether...
Cohort studies report inconsistent associations between fish consumption, a major source of long-chain ω-3 fatty acids, and risk cardiovascular disease (CVD) mortality. Whether the vary those with without vascular is unknown.To examine whether consumption CVD or mortality differ individuals disease.This pooled analysis individual participant data involved 191 558 from 4 cohort studies-147 645 (139 827 7818 CVD) 21 countries in Prospective Urban Rural Epidemiology (PURE) study 43 413 patients...
Objectives We aimed to examine the relationship between access medicine for cardiovascular disease (CVD) and major adverse events (MACEs) among people at high risk of CVD in high-income countries (HICs), upper lower middle-income (UMICs, LMICs) low-income (LICs) participating Prospective Urban Rural Epidemiology (PURE) study. Methods defined as presence any following: hypertension, coronary artery disease, stroke, smoker, diabetes or age >55 years. Availability affordability blood...
<h3>Importance</h3> Stress may increase the risk of cardiovascular disease (CVD). Most studies on stress and CVD have been conducted in high-income Western countries, but whether is associated with other settings has less well studied. <h3>Objective</h3> To investigate association a composite measure psychosocial development events mortality large prospective study involving populations from 21 high-, middle-, low-income countries across 5 continents. <h3>Design, Setting, Participants</h3>...
Objective To evaluate the performance of non-laboratory INTERHEART risk score (NL-IHRS) to predict incident cardiovascular disease (CVD) across seven major geographic regions world. The secondary objective was fasting cholesterol-based IHRS (FC-IHRS). Methods Using measures discrimination and calibration, we tested NL-IHRS (n=100 475) FC-IHRS (n=107 863) for predicting CVD in a community-based, prospective study regions: South Asia, China, Southeast Middle East, Europe/North America, America...
Koronární ektázie (coronary artery ectasia - CAE) je definována jako lokalizované nebo difuzní rozšíření lumen koronární tepny o více než 1,5násobek průměru největší přilehlé nepostižené tepny. U pacientů absolvujících koronarografické vyšetření se incidence CAE uvádí v rozmezí 0,3-4,9 %. Vyhledávání osob s tímto postižením může zvýšit při použití nových neinvazivních zobrazovacích metod, např. výpočetní tomografie (computed tomography CT) a MR angiografie. Za hlavní etiologický faktor...
Nonalcoholic fatty liver disease (NAFLD) is a multisystem and significantly associated with obesity, insulin resistance, type 2 diabetes mellitus, metabolic syndrome, cardiovascular disease.NAFLD has become the most prevalent chronic in Western countries, proportion of NAFLD-related cirrhosis among patients on transplantation waiting lists increased.In light accumulated data about NAFLD, to provide common approach multi-disciplines dealing subject, it necessary create new guidance for...
In vitro studies have shown that C-reactive protein (CRP) attenuates nitric oxide production and inhibits angiogenesis, which may result in impaired collateral development. The aim of this study was to investigate the association between high sensitivity CRP (hsCRP) levels extent coronary collaterals.We investigated hsCRP collaterals according Rentrop classification a cohort 185 patients who had high-grade stenosis or occlusion on their angiograms.Mean age 62 years 80% were males. Subjects...
Objective The relationship between androgens and the risk of development coronary artery disease has not been clarified well. This study was planned to determine serum androgen levels premature in men. Methods Sixty-nine men below 45 years age with documented (mean 41.0±4.7) constituted group. Control group consisted 56 similar normal angiograms 41.3±3.8). Total free testosterone, estradiol, fasting plasma total, low-density lipoprotein, high-density lipoprotein cholesterol, triglyceride...
Experimental data suggest that tissue factor (TF) may induce neointimal hyperplasia after arterial injury. In this study, we investigated the hypothesis elevated levels of TF in circulation contribute to development restenosis percutaneous transluminal coronary angioplasty (PTCA) or stent implantation.Whole-blood procoagulant activity (TF-PCA) was measured using a previously described assay before, at 3 hours after, and 24 intervention 61 patients with stable angina undergoing PTCA (n=20)...
Amiodarone-induced thyrotoxicosis (AIT) is a complex therapeutic challenge. Two major forms have been described: type I and II. Methimazole (MMI) potassium perchlorate (KCLO4) the treatment of choice for former, whereas corticosteroids are used latter. However, mixed appear frequently it not easy to prescribe because side effects. The present study investigated validity stepwise approach AIT. Twenty patients with AIT were given 30–50 mg/d MMI 1000 KCLO4 initially month. Euthyroidism or...