A5049221969- COVID-19 Clinical Research Studies
- Neuropeptides and Animal Physiology
- Retinoids in leukemia and cellular processes
- Inflammasome and immune disorders
- Diet and metabolism studies
- SARS-CoV-2 and COVID-19 Research
- Aquaculture Nutrition and Growth
- Lipid Membrane Structure and Behavior
- Retinal Development and Disorders
- Pharmacological Receptor Mechanisms and Effects
- Cardiovascular Health and Risk Factors
- Neuroendocrine regulation and behavior
- Hypothalamic control of reproductive hormones
- Long-Term Effects of COVID-19
- Aquaculture disease management and microbiota
- Neurosurgical Procedures and Complications
- Cardiovascular, Neuropeptides, and Oxidative Stress Research
- Pharmaceutical Economics and Policy
- Nutritional Studies and Diet
- RNA regulation and disease
- COVID-19 epidemiological studies
- Heart Failure Treatment and Management
- Neuroinflammation and Neurodegeneration Mechanisms
- Neuroscience and Neuropharmacology Research
- Mechanical Circulatory Support Devices
Instituto Cardiovascular de Rosario
2021-2025
Estudios Clínicos Latinoamérica
2024-2025
Universidade da Coruña
2001-2019
Hospital Universitario De Cabueñes
2003
<h3>Importance</h3> Hospitalized patients with COVID-19 pneumonia have high rates of morbidity and mortality. <h3>Objective</h3> To assess the efficacy colchicine in hospitalized pneumonia. <h3>Design, Setting, Participants</h3> The Estudios Clínicos Latino América (ECLA) Population Health Research Institute (PHRI) COLCOVID trial was a multicenter, open-label, randomized clinical performed from April 17, 2020, to March 28, 2021, adults confirmed or suspected SARS-CoV-2 infection followed for...
ABSTRACT There are limited data on individual risk factors for SARS-CoV-2 infection (including unrecognized infection). In this seroepidemiologic substudy of an ongoing prospective cohort study community-dwelling adults, participants were thoroughly characterized pre-pandemic. The was ascertained by serology. Among 8,719 from 11 high-, middle-, and low-income countries, 3,009 (35%) seropositive SARS-CoV-2. Characteristics independently associated with seropositivity younger age (odds ratio,...
Abstract The distribution of thyrotropin‐releasing hormone (TRH) in the brain adult zebrafish was studied with immunohistochemical techniques. In telencephalon, abundant TRH‐immunoreactive (TRHir) neurons were observed central, ventral, and supra‐ postcommissural regions ventral telencephalic area. diencephalon, TRHir anterior parvocellular preoptic nucleus, suprachiasmatic lateral hypothalamic rostral parts tuberal nucleus torus lateralis, posterior nucleus. Some also central thalamic...
Abstract Aims Cardiogenic shock (CS) is linked to high morbidity and mortality rates, posing a challenge for clinicians. Interventions improve tissue perfusion blood pressure are crucial prevent further deterioration. Unfortunately, current inotropes, which act through adrenergic receptor stimulation, associated with malignant arrhythmias poorer outcomes. Due its unique mechanism of action, istaroxime should haemodynamics without overactivation. The SEISMiC study designed examine the safety...
Abstract Background Megalencephalic Leukoencephalopathy with subcortical Cysts (MLC) is a rare type of leukodystrophy characterized by astrocyte and myelin vacuolization, epilepsy early-onset macrocephaly. MLC caused mutations in MLC1 or GLIALCAM , coding for two membrane proteins an unknown function that form complex specifically expressed astrocytes at cell-cell junctions. Recent studies Mlc1 −/− Glialcam mice mlc1 zebrafish have shown regulates glial surface levels GlialCAM vivo also...
Background Current strategies to prevent adverse cardiovascular outcomes focus on secondary prevention and primary in high-risk groups. The proportion of events occurring lower-risk groups globally is unknown. Methods We prospectively documented fatal or non-fatal myocardial infarction, stroke, heart failure, any other event stratified by history disease (CVD), the INTERHEART Framingham risk score those without prior CVD, 189,097 adults from 26 high-, middle- low-income countries. Results...
The development and adult distribution of thyrotropin-releasing hormone-immunoreactive (TRHir) neurons in the brain brown trout, Salmo trutta fario, was studied with streptavidin-biotin immunohistochemical method. Study embryos, alevin, juveniles revealed groups TRHir mesencephalon rhombencephalon that have not been noted previously teleosts. earliest cells observed were those trigeminal motor nucleus, which expressed this substance only embryos alevins. In forebrain, early-arising TRH...