A5018627967- Helicobacter pylori-related gastroenterology studies
- Gastrointestinal disorders and treatments
- Eosinophilic Esophagitis
- Celiac Disease Research and Management
- Esophageal and GI Pathology
- Liver Disease Diagnosis and Treatment
- Gastroesophageal reflux and treatments
- Inflammasome and immune disorders
- Tracheal and airway disorders
- Microscopic Colitis
- Child Nutrition and Feeding Issues
- Rabies epidemiology and control
- Inflammatory Bowel Disease
- Cystic Fibrosis Research Advances
- Autoimmune and Inflammatory Disorders Research
- Immunodeficiency and Autoimmune Disorders
- Liver physiology and pathology
- Pancreatitis Pathology and Treatment
- Pancreatic and Hepatic Oncology Research
- Asthma and respiratory diseases
- Neonatal Respiratory Health Research
- Child Nutrition and Water Access
- Streptococcal Infections and Treatments
- Nutrition and Health in Aging
- Diabetes and associated disorders
Marmara University
2008-2024
Maltepe University
2022
Dr Lütfi Kırdar Kartal Eğitim ve Araştırma Hastanesi
2012-2019
Acıbadem Kadıköy Hospital
2013
Istanbul University
2004
Studies of monogenic gastrointestinal diseases have revealed molecular pathways critical to gut homeostasis and enabled the development targeted therapies.
Nonalcoholic fatty liver disease (NAFLD) is a multisystem and significantly associated with obesity, insulin resistance, type 2 diabetes mellitus, metabolic syndrome, cardiovascular disease.NAFLD has become the most prevalent chronic in Western countries, proportion of NAFLD-related cirrhosis among patients on transplantation waiting lists increased.In light accumulated data about NAFLD, to provide common approach multi-disciplines dealing subject, it necessary create new guidance for...
There has been a marked decrease in the eradication rates of Helicobacter pylori infection with standard triple therapy worldwide. Hence, sequential gained attention as promising treatment during last few years. This study was carried out to compare efficacy versus context clarithromycin (CLA) resistance.In this study, children between 3 and 18 years age, who had documented H. infection, were randomized receive either or therapy. ascertained using C-urea breath test 4-6 weeks after...
INTRODUCTION The etiology of gastric outlet obstruction (GOO) may vary according to the age patient, and it usually develops as a complication Helicobacter pylori-associated peptic ulcer disease in adults (1-3). Although malignant tumors account for up 40% cases GOO adulthood, is not case children (4). In addition congenital abnormalities such annular pancreas, antral web bands, corrosive gastritis well prolonged use nonsteroidal anti-inflammatory drugs be associated with during childhood...
Abstract Background An inverse association has been suggested between celiac disease (CD) and Helicobacter pylori ( Hp ) infection in children; however, there are inconsistent data. The purpose of this multi‐center study is to evaluate the CD childhood. Methods Children who underwent endoscopy July 2016 November 2017 four pediatric gastroenterology centers were included study. Patients with a history previous eradication, antibiotic or acid‐suppressive drug therapy last 4 weeks, any...
It has been reported that 5-50% of patients with primary immune deficiencies (PID) may present or develop gastrointestinal (GI) manifestations.This study was aimed at analyzing GI and related endoscopic, histopathological findings in children PID.Children PID who were evaluated by endoscopy between 2005 2016 enrolled this study. Demographic data, growth parameters, signs symptoms diagnosis obtained.Of 425 PID, 195 had manifestations. Forty-seven required endoscopic investigation, 30 (63.8%)...
<b><i>Background and Objectives:</i></b> Bowel preparation (BP) for colonoscopy is a challenging procedure in children different regimens have been used this purpose. Polyethylene glycol (PEG) the most preferred agent recent years. The primary aim of study was to evaluate efficacy 1-day PEG-3350 with bisacodyl (PEG-B) comparing it 3-day sennosides A+B. <b><i>Method:</i></b> In prospective, randomized, single-blinded study, aged 2–18 years were...
Aim Although the relationship between 25-hydroxy (25-OH) vitamin D and asthma is known, it unknown if 25-OH levels are correlated with severity in pediatric patients. The aim of this study was to compare blood patients healthy control groups evaluate any correlation Methods This a cross-sectional which shows compared controls followed by tertiary clinic. We investigated effect on asthma. determined mainly duration diagnosis, number attacks previous year, anti-inflammatory medication usage...
The aim of the study was to evaluate familial Mediterranean fever (FMF) mutation analysis in pediatric patients with inflammatory bowel disease (IBD). relation between MEFV mutations and chronic diseases has been reported previously.Children IBD (334 ulcerative colitis (UC), 224 Crohn's (CD), 39 indeterminate (IC)) were tested for FMF this multicenter study. distribution according type, histopathological findings, activity indexes determined.A total 597 children (mean age: 10.8 ± 4.6 years,...
Protein-losing enteropathy may develop as a complication of wide spectrum diseases. Three cases giardiasis that presented with acute onset hypoalbuminemia were documented, and resolution protein loss after treatment was also confirmed. Thus, chronic enteric infections should be considered an etiology severe intestinal loss, particularly in children.
Autoimmune pancreatitis has been described as a pancreatic manifestation of immunoglobulin G4-related disease, which is characterized by typical histopathologic, radiologic, and clinical features. Immunoglobulin disease usually accompanied elevated serum G4 level, can involve multiple organ/systems. rarely reported in pediatric population. There are few reports inflammatory bowel association with disease. We describe 7-year-old girl who presented concurrent sclerosing cholangitis, developed...
Delivery of supplemental oxygen is the initial vital management hypoxemic acute lower respiratory infection (HALRI). Oxygen delivery systems include low-flow and high-flow devices. In devices such as Venturi mask, a constant mixture delivered. As result, increased rate breathing does not affect concentration this study, we compared efficacy masks in hypoxemia pediatric patients.A total 65 children, aged 3-36 months, diagnosed with HALRI, were enrolled. Patients allocated into groups, via...
The aim of this study was to evaluate the consistency Savary-Miller, Hetzel-Dent and Los Angeles endoscopic classification systems compare them with esophageal histopathology in children.Children between ages 5-17 years who underwent esophagogastroduodenoscopy were included study. reports still images esophagus reclassified by same gastroenterologist according Hetzel- Dent scoring systems. biopsies also reevaluated pathologist histopathologic esophagitis evaluated.A total 113 out 192...
Low serum titer of anti-tissue transglutaminase (tTG) has been described in various conditions without any evidence celiac disease (CD). Infectious agents have suggested to trigger autoimmunity and promote the production anti-tTG. The aim this study was investigate if there is a link between positive serology concomitant Helicobacter pylori infection children.The data 178 pediatric patients who underwent upper gastrointestinal endoscopy due were compiled. whose histopathologic findings not...
Paracetamol is the most commonly used analgesic after cleft palate repair. It has rarely caused acute hepatic failure at therapeutic or supratherapeutic doses. Only one case of paracetamol toxicity repair had been reported previously. Here, we present a similar patient who developed liver and encephalopathy an uncomplicated surgery. Lack large prospective trials in young children due to ethical concerns increases value reports acetaminophen The dosing recommendations may need be reconsidered
Colorectal cancer (CRC) is very rare those younger than 20 years of age with an annual incidence 1 case per million individuals (1). While a majority the published CRC cases were older adolescents, reports including pediatric series are limited in number (2,3). Hence, overlooked differential diagnosis unexplained abdominal pain, weight loss, and anemia children (4). At presentation, usually at advanced-stages disease have higher frequency unfavorable histopathology, consequently poor outcome...
This study aims to assess the effect of adenoid hypertrophy on asthma in children with mild asthma.Between September 2010 and 2012, 63 (42 males, 21 females; median age 10.5 years; range 6 14 years) admitted our clinic complaint were included this study. These evaluated for hypertrophy, symptoms asthma, medical treatment, pulmonary function tests at beginning end second month.There was no correlation between initial hypertrophy. But we observed significantly lower forced vital capacity...