A5090720320- Air Quality and Health Impacts
- Noise Effects and Management
- Indoor Air Quality and Microbial Exposure
- Climate Change and Health Impacts
- Allergic Rhinitis and Sensitization
- Asthma and respiratory diseases
- Air Quality Monitoring and Forecasting
- Pediatric health and respiratory diseases
- Energy and Environment Impacts
- Chronic Obstructive Pulmonary Disease (COPD) Research
- Urban Green Space and Health
- Effects and risks of endocrine disrupting chemicals
- Vehicle emissions and performance
- Dermatology and Skin Diseases
- Respiratory viral infections research
- Thermoregulation and physiological responses
- Pneumonia and Respiratory Infections
- Olfactory and Sensory Function Studies
- Global Health Care Issues
- Energy, Environment, and Transportation Policies
- Birth, Development, and Health
- Gut microbiota and health
- Occupational exposure and asthma
- Thermal Regulation in Medicine
- Food Security and Health in Diverse Populations
Fudan University
2016-2025
National Health and Family Planning Commission
2017-2024
Shanghai Meteorological Bureau
2022-2024
University of Chinese Academy of Sciences
2021-2022
Chinese Academy of Sciences
2004-2022
Shanghai Institute of Materia Medica
2021-2022
Boston University
2017
Shanghai Tenth People's Hospital
2017
Tongji University
2017
Icahn School of Medicine at Mount Sinai
2017
Evidence concerning the acute health effects of air pollution caused by fine particulate matter (PM2.5) in developing countries is quite limited.To evaluate short-term associations between PM2.5 and daily cause-specific mortality China.A nationwide time-series analysis was performed 272 representative Chinese cities from 2013 to 2015. Two-stage Bayesian hierarchical models were applied estimate regional- national-average concentrations mortality. City-specific estimated using overdispersed...
Background: Exposure to ambient particulate matter (PM) is associated with a number of adverse health outcomes, but potential mechanisms are largely unknown. Metabolomics represents powerful approach study global metabolic changes in response environmental exposures. We therefore conducted this investigate serum metabolites the reduction PM exposure among healthy college students. Methods: randomized, double-blind crossover trial 55 students Shanghai, China. Real and sham air purifiers were...
Although mounting evidence has associated air pollution and environmental temperature with children's health problems, it is unclear whether there an interaction between these factors on childhood asthma. To explore the effects of temperature-pollution interactions during pre- post-natal periods asthma among pre-schoolers. A retrospective cohort study 39,782 pre-schoolers was performed 2010–2012, in seven cities China. Exposure to three indicators (TI) critical ambient pollutants, including...
There are few studies on associations between children's respiratory heath and air pollution in schools China. The industrial development increased traffic may affect the indoor exposure to pollutants school environment. Moreover, there is a need study effects of environmental tobacco smoke (ETS) emissions from new building materials homes
MicroRNAs (miRNAs) are a key factor in epigenetic regulation of gene expression, but miRNA responses to fine particulate matter (PM2.5) air pollution and their potential contribution cardiovascular effects PM2.5 unknown.We explored the influence on expression selected cytokines relevant systemic inflammation, coagulation, vasoconstriction, miRNAs that may regulate expression.We designed double-blind, randomized crossover study which true sham purifiers were used expose 55 healthy young adult...
We studied indoor sources of particulate matter (PM), outdoor air pollution and antibiotic use in relation to asthma, rhinitis eczema among pre-school children investigated synergistic effects between PM antibiotics use. Children (3-6y) from randomly selected day care centres seven cities across China were included (n = 39,782). Data on ambient temperature collected local monitoring stations. (ETS, burning incense or mosquito coils biomass for cooking), health (doctor diagnosed asthma...
Limited evidence is available on the effects of various fine particulate matter (PM2.5) constituents blood inflammation and coagulation. We examined associations between 10 circulating biomarkers in a panel 28 urban residents with four repeated measurements Shanghai, China. Based linear mixed-effect models, we fitted single-constituent constituent-PM2.5 joint constituent-residual models to evaluate PM2.5 eight inflammatory (fibrinogen, C-reactive protein, monocyte chemoattractant protein-1,...
It remains unknown how fine particulate matter (PM2.5) constituents affect differently the fractional concentration of exhaled nitric oxide (FeNO, a biomarker airway inflammation) and DNA methylation its encoding gene (NOS2A). We aimed to investigate short-term effects PM2.5 on NOS2A FeNO. designed longitudinal study among chronic obstructive pulmonary disease (COPD) patients with six repeated health measurements in Shanghai, China. applied linear mixed-effect models evaluate associations....
Short-term associations between size-fractionated particulate air pollution and circulating biomarkers are not well established, especially in developing countries with high levels of matter (PM).We designed a panel study involving 34 healthy young adults to evaluate acute effects PM on 13 inflammation, coagulation, vasoconstriction. We measured real-time, number concentrations (aerodynamic diameters from 0.25 10 μm, mass < μm) over four follow-up measurements. The short-term were assessed...
Few longitudinal studies exist on childhood exposure to indoor and outdoor air pollution respiratory illness in China. We studied associations between environment prevalence, onset remission of wheeze rhinitis among children across Children (3–6 y) were recruited from randomized day care centres six cities. The main data analysis was restricted not moving since birth (N = 17,679). Data wheeze, the home assessed by a parental questionnaire. Prevalence first two years life (baseline) last year...
Fireworks displays are a traditional form of celebration during the Chinese Spring Festival (Festival). In response to heavy air pollution caused by fireworks, Shanghai, megacity in China, has imposed regulatory measures on use fireworks recent years. To investigate quality trends before and after firework regulation was established quantify its efficiency, gaseous pollutants, PM2.5 levels, chemical composition were synchronously measured at 1 h time intervals an urban site suburban Shanghai...
Practical approaches to protect individuals from ambient particulate matter (PM) are urgently needed in developing countries. Evidence on the health benefits of wearing particulate-filtering respirators is limited.We evaluated short-term cardiovascular effects China.A randomized crossover trial was performed 24 healthy young adults Shanghai, China 2014. The subjects were into two groups and wore for 48 hr alternating with a 3-week washout interval. Heart rate variability (HRV) ambulatory...
We estimated associations between ambient air pollution, home environment and asthma as well rhinitis among adults across China. A total of 40,279 young from eight Chinese cities participated in a questionnaire survey (participation rate 75%). There were questions on health environment. Information city level gross domestic product (GDP) per capita, temperature PM10 NO2 collected registers. Two-level logistic regression models used to study associations. Totally 1.6% reported 6.6% allergic...