A5080686859- Liver Disease Diagnosis and Treatment
- Peroxisome Proliferator-Activated Receptors
- Diabetes, Cardiovascular Risks, and Lipoproteins
- Nutritional Studies and Diet
- Cardiovascular Health and Risk Factors
- Metabolism, Diabetes, and Cancer
- Lipid metabolism and disorders
- Adipose Tissue and Metabolism
- Cancer Risks and Factors
- Traffic and Road Safety
- Obesity, Physical Activity, Diet
- Cancer-related molecular mechanisms research
- Nutrition, Genetics, and Disease
- Colorectal Cancer Screening and Detection
- Injury Epidemiology and Prevention
- Cancer, Lipids, and Metabolism
- Healthcare Systems and Reforms
- Cancer, Hypoxia, and Metabolism
- Esophageal Cancer Research and Treatment
- Hepatitis B Virus Studies
- Cardiovascular Disease and Adiposity
- Birth, Development, and Health
- Hepatitis C virus research
- RNA modifications and cancer
- Adipokines, Inflammation, and Metabolic Diseases
Peking Union Medical College Hospital
2025
Jiangsu Provincial Center for Disease Control and Prevention
2016-2025
Chinese Academy of Medical Sciences & Peking Union Medical College
2025
Southeast University
2016-2025
Nanjing Medical University
2012-2024
Harbin Medical University
2024
Aquinas Institute of Theology
2024
Capital Medical University
2024
Suzhou Research Institute
2024
Peking University
2006-2023
Limited population‐based cancer registry data available in China until now has hampered efforts to inform control policy. Following extensive improve the systematic surveillance this country, we report on largest pooled analysis of survival date. Of 21 registries, from 17 registries ( n = 138,852 records) were included final analysis. Cases diagnosed 2003–2005 and followed end 2010. Age‐standardized relative was calculated using region‐specific life tables for all cancers combined 26...
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Background: To date, large amounts of epidemiological and case study data have been available for the Coronavirus Disease 2019 (COVID-19), which suggested that mortality was related to not just respiratory complications. Here, we specifically analyzed kidney functions in COVID-19 patients their relations mortality.Methods: In this multi-centered, retrospective, observational study, included 193 adult with laboratory-confirmed from 2 hospitals Wuhan, 1 hospital Huangshi (Hubei province, 83 km...
Abstract Background Thymosin alpha 1 (Tα1) had been used in the treatment of viral infections as an immune response modifier for many years. However, clinical benefits and mechanism Tα1 COVID-19 patients are still unclear. Methods We retrospectively reviewed outcomes 76 severe cases admitted to 2 hospitals Wuhan, China, from December 2019 March 2020. The thymus output peripheral blood mononuclear cells was measured by T-cell receptor excision circles (TRECs). levels exhaustion markers...
LncRNA SPRY4-IT1 has been shown to promote the progression of melanoma. However, role lncRNA in human esophageal squamous cell carcinoma (ESCC) remains unclear. The purpose this study is investigate clinical significance and biological functions ESCC. expression levels SPRY4-IT 92 ESCC patients 8 lines were evaluated by quantitative reverse transcriptase polymerase chain reaction (qRT-PCR). prognostic was using Kaplan–Meier Cox regression analyses. Small interfering RNA (siRNA) used suppress...
Breastfeeding confers substantial benefits to child health and has also been associated with lower risk of maternal cardiovascular diseases (CVDs) in later life. However, the evidence on effects CVD is still inconsistent, especially East Asians, whom frequency duration breastfeeding significantly differ from those West.In 2004-2008, nationwide China Kadoorie Biobank recruited 0.5 million individuals aged 30 79 years 10 diverse regions across China. During 8 follow-up, 16 671 incident cases...
Abstract Epidemiological studies suggested drinking green tea is inversely associated with esophageal cancer but results remain inconclusive. Moreover, inconsistent observations found high temperature drinks are cancer. A population‐based case–control study was conducted in a high‐risk area (Dafeng) and low‐risk (Ganyu) of Jiangsu province China from 2003 to 2007. It aimed explore the risk cancer, compare difference between different regions. Using identical protocols, 1,520 cases 3,879...
Visceral adiposity index (VAI), a novel sex-specific for visceral fat measurement, has been proposed recently. We evaluate the efficacy of VAI in identifying diabetes risk Chinese people, and compare predictive ability between other body fatness indices, i.e., waist circumference (WC), mass (BMI) waist- to- height ratio (WHtR). Participants (n = 3,461) were recruited from an ongoing cohort study Jiangsu Province, China. Hazard (HR) corresponding 95% confidence interval (CI) different indices...
Background Electric bike (E-bike)-related deaths have been increasing rapidly in China and such injuries may be partly attributable to unsafe riding practice. Objectives To describe potentially behaviours among electric bikers (E-bikers) investigate factors influencing these practices China. Methods In September 2012, a cross-sectional observation study including speed measurement component was conducted Wuzhong (an urban district) Zhangjiagang (a rural of Suzhou, Jiangsu Province, Hand-held...
Objective: Electric bike/moped-related road traffic injuries have become a burgeoning public health problem in China. The objective of this study was to identify the prevalence and potential risk factors electric among bike/moped riders southern China.Methods: A cross-sectional used interview 3,151 that occurred from July 2014 June 2015 were investigated. Data collected by face-to-face interviews analyzed between 2017.Results: investigated 15.99%. significantly associated with category bike...
China implemented containment measures to stop SARS-CoV-2 transmission in response the COVID-19 epidemic. After first epidemic wave, we conducted population-based serological surveys determine extent of infection, risk factors for and neutralization antibody levels assess real infections random sampled population.We used a multistage, stratified cluster sampling strategy conduct three areas - Wuhan, Hubei Province outside six provinces selected on incidence strategy. Participants were...
Abstract Lung adenocarcinoma (LUAD) is a malignant tumor with high lethality, and the aim of this study was to identify promising biomarkers for LUAD. Using TCGA-LUAD dataset as discovery cohort, novel joint framework VAEjMLP based on variational autoencoder (VAE) multilayer perceptron (MLP) proposed. And Shapley Additive Explanations (SHAP) method introduced evaluate contribution feature genes classification decision, which helped us develop biologically meaningful biomarker potential...
Background: Chinese women's reproductive patterns have changed significantly over the past several decades. However, relatively little is known about pace and characteristics of these changes either overall or by region socioeconomic status. Methods: We examined cross-sectional data from China Kadoorie Biobank cohort study that recruited 300 000 women born between 1930 1974 (mean age: 51 years) 10 socially diverse urban rural regions China. Temporal trends in self-reported characteristics,...
Police reports indicate an increasing burden of electric bike (E-bike) casualties in China; however, hospitalised injury data have not been reported. The aim the present work was to describe patterns for E-bikers involved road crashes and explore risk disparities among them. For period October 2010 April 2011, this cross-sectional study retrospectively collected information from hospital records, Suzhou China, using International Classification Diseases , 10th revision (ICD-10) diagnosis...
Although the association for esophageal cancer with tobacco smoking and alcohol drinking has been well established, risk appears to be less strong in China. To provide more evidence on effect of consumption China, particularly among Chinese women, a population-based case-control study conducted Jiangsu, from 2003 2007. A total 1,520 cases 3,879 controls were recruited. Unconditional multivariate logistic regression analysis was applied. Results showed that odds ratio (OR) confidence interval...
Protective effect of garlic on the development cancer has been reported in vitro and vivo experimental studies; however, few human epidemiologic studies have evaluated relationship. A population-based case-control study conducted a Chinese population from 2003 to 2010, with aim explore association between raw consumption lung cancer. Epidemiologic data were collected by face-to-face interviews using standard questionnaire among 1,424 cases 4,543 healthy controls. Unconditional logistic...
Cancer is a major public health burden both globally and in China. The most common cancer-related deaths China are attributable to cancers of the lung, liver, stomach, esophagus. Previous epidemiologic studies on cancer have often been limited by small sample sizes, inconsistent measurements, lack precise accurate data. Jiangsu Four Cancers (JFC) Study population-based case–control study carried out an effort obtain consistent high-quality data investigate life style, behavioral,...
The long-term characteristics of anti-SARS-CoV-2 antibodies among COVID-19 patients remain largely unclear. Tracking the longevity these can provide a forward-looking reference for monitoring COVID-19.