A5083839076- Orthopaedic implants and arthroplasty
- Orthopedic Infections and Treatments
- Bone Tissue Engineering Materials
- Hip disorders and treatments
- Bone fractures and treatments
- Total Knee Arthroplasty Outcomes
- Hip and Femur Fractures
- 3D Printing in Biomedical Research
- Carbon Nanotubes in Composites
- Osteoarthritis Treatment and Mechanisms
- Traffic and Road Safety
- Health disparities and outcomes
- Injury Epidemiology and Prevention
- Fiber-reinforced polymer composites
- Knee injuries and reconstruction techniques
- Agriculture and Farm Safety
- Bone and Joint Diseases
- Reconstructive Surgery and Microvascular Techniques
- Wound Healing and Treatments
- Anatomy and Medical Technology
- Birth, Development, and Health
- Musculoskeletal synovial abnormalities and treatments
- Electrospun Nanofibers in Biomedical Applications
- Mechanical Behavior of Composites
- Lymphatic System and Diseases
Zhejiang University
2004-2025
Jinhua Central Hospital
2025
Nanjing Drum Tower Hospital
2025
Xiangya Hospital Central South University
2009-2023
Central South University
2009-2023
Medical Research Council
2023
University of Oxford
2023
First Affiliated Hospital Zhejiang University
2023
Weatherford College
2021
Karamay Central Hospital
2021
Mean blood pressure varies moderately with outdoor air temperature in many western populations. Substantial uncertainty exists, however, about the strength of relationship other populations and its relevance to age, adiposity, medical treatment, climate housing conditions.To investigate season temperature, we analysed cross-sectional data from China Kadoorie Biobank study 506,673 adults aged 30-79 years recruited 10 diverse urban rural regions China. Analyses related mean - overall various...
Infected bone defects (IBDs) remains a challenging problem for orthopedists. Clinically, routine management IBDs has two stages: debridement and systematic antibiotics administration to control infection, secondary grafting repair defects. Whereas the efficacy is not satisfactory, because overuse of may lead systemic toxicity, emergence drug-resistant bacteria, as well surgery would cause additional trauma economic burden patients. Therefore, it imperative develop novel scaffold one-stage...
Background Electric bike (E-bike)-related deaths have been increasing rapidly in China and such injuries may be partly attributable to unsafe riding practice. Objectives To describe potentially behaviours among electric bikers (E-bikers) investigate factors influencing these practices China. Methods In September 2012, a cross-sectional observation study including speed measurement component was conducted Wuzhong (an urban district) Zhangjiagang (a rural of Suzhou, Jiangsu Province, Hand-held...
Introduction Rheumatoid arthritis (RA) is an autoimmune disease and closely associated with both genetic environmental factors. Volatile organic chemicals (VOC), a common environment pollutant, was some diseases, while whether VOC exposure or which leads to RA yet clarified. Methods A cross-sectional study using data from the 6 survey cycles (2005-2006, 2011-2012, 2013-2014, 2015-2016, 2017-2018, 2017-2020) of NHANES program performed. The non-arthritis status participant identified through...
Abstract Background Nurse anesthetists in the post-anesthetic care unit (PACU) of Gastrointestinal Endoscopy Center monitor and manage complications following endoscopy procedures. We examined impact nurse anesthetist scheduling patterns on resuscitation efficiency inflammatory bowel disease (IBD) patients anesthesia recovery room after painless gastrointestinal endoscopy. Methods This was a retrospective analysis IBD who underwent at large tertiary clinic. Two anesthetic practitioner models...
Background: This study aims to analyze the clinical characteristics and factors influencing postoperative limb function recovery in patients with acute type A aortic dissection (ATAAD) complicated by lower extremity malperfusion (LEM). The objective is accurately assess preoperative conditions, identify manage risk factors, improve surgical techniques, offer insights enhance rate of LEM following surgery. Methods: retrospective included 131 ATAAD LEM, admitted Department Cardiothoracic...
Women's parity has been associated with risk of cardiovascular disease (CVD). It is unclear, however, whether it reflects biological effects childbearing or uncontrolled socio-economic and lifestyle factors childrearing. We assessed the association between number children incident CVD outcomes separately in women men.In 2004-08, nationwide China Kadoorie Biobank recruited 0.5 million individuals aged 30-79 years from 10 diverse regions. During 7 follow-up, 24 432 cases coronary heart (CHD)...
Treatment of bone and joint tuberculosis remains a challenge. The development tissue-engineered drug-loaded biomaterials has increased the therapeutic options. However, for treatment osteoarticular with severe local infection risks high weight-bearing requirements, it is still necessary to design materials consistent biomechanics, cytocompatibility, osteogenesis provide more effective antimicrobial functions. antitubercular drugs isoniazid rifampicin are loaded gellan gum, 3D-printed porous...
3D-printed porous tantalum scaffold has been increasingly used in arthroplasty due to its bone-matching elastic modulus and good osteoinductive ability. However, the lack of antibacterial ability makes it difficult for prevent occurrence development periprosthetic joint infection. The difficulty high cost curing infection (PJI) revision surgery limit further clinical application tantalum. Therefore, we fabricated vancomycin-loaded scaffolds by combining chemical grafting...
Abstract Background Poly(vinyl alcohol) (PVA) hydrogels have been widely used in synthetic cartilage materials. However, limitations of PVA such as poor biomechanics and limited cell ingrowth remain challenges this field. Methods This work aimed to design novel nano-hydroxyapatite (nano-HA)/poly(vinyl coated with a poly(lactic-co-glycolic acid) (PLGA)/nano-HA/PVA scaffold counter the hydrogels. The core, comprising nano-HA/PVA hydrogel, had primary role bearing mechanical load. peripheral...
Abstract In this study, the deformation behavior of high density polyethylene (HDPE) and its nanocomposites under uniaxial static dynamic compression loadings were experimentally investigated. The nanofillers used carbon nanofibers (CNF) with surface treatments pristine graphite nanoplatelets (GNP) respectively. tests performed at strain rates 1 × 10 3 , 4 7 /s using split Hopkinson pressure bar done rate −2 /s. addition, microstructual examinations to gain insights into observed macroscopic...
Abstract [Background] On January 7, 2020, the novel coronavirus named "COVID-19" aroused worldwide concern was identified by Chinese scientists. Many related research works were developed for emerging, rapidly evolving situation of this epidemic. This study aimed to analyze literatures on SARS, MERS and COVID-19 retrieve important information virologists, epidemiologist policy decision makers. [Methods] In study, we collected data from multi sources compared bibliometrics indices among...
Polyvinyl alcohol (PVA) hydrogel has gained interest in cartilage repair because of its highly swollen, porosity, and viscoelastic properties. However, PVA some deficiencies, such as poor biocompatibility microstructure. This research aimed to design novel hydroxyapatite (HA)-collagen (COL)-PVA hydrogels. COL was added improve cell biocompatibility, the microstructure hydrogels controlled by fused deposition modeling (FDM). The feasibility COL-HA-PVA evaluated vitro vivo experiments....
Whether antibiotics should be included remains greatly debated in Masquelet technique. This study intended to determine the effect of polymethyl methacrylate (PMMA) spacer loaded with different vancomycin concentrations on bone defect repair. Hollow cylindrical spacers consisting PMMA and varying (0, 1, 2, 4, 6, 8, 10 g) were prepared. Critical defects rabbits created at radial shaft, implanted subsequently intramedullary fixed retrograde Kirschner's wires (n = 4 for each concentration)....
Charcot joint disease is a rare neurogenic lesion of the characterized by progressive destruction with dislocation or subluxation. However, whether replacement should be performed for severe damage controversial.This paper reports case large bone defect that was treated arthroplasty assisted customized 3D-printed porous tantalum. The patient admitted to hospital 9-year history bilateral knee pain had aggravated in past 2 months. Radiography showed osteogeny and sclerosis both knees, free...