A5103176875- Global Cancer Incidence and Screening
- Esophageal Cancer Research and Treatment
- Gastric Cancer Management and Outcomes
- Cancer Risks and Factors
- Colorectal Cancer Screening and Detection
- RNA modifications and cancer
- Esophageal and GI Pathology
- Lung Cancer Diagnosis and Treatment
- Cancer-related molecular mechanisms research
- Lung Cancer Treatments and Mutations
- Multiple and Secondary Primary Cancers
- MicroRNA in disease regulation
- Nutrition, Genetics, and Disease
- Air Quality and Health Impacts
- Epigenetics and DNA Methylation
- Cancer Genomics and Diagnostics
- Medical Research and Treatments
- Circular RNAs in diseases
- Trace Elements in Health
- Cancer, Lipids, and Metabolism
- Liver Disease Diagnosis and Treatment
- Breast Cancer Treatment Studies
- Bladder and Urothelial Cancer Treatments
- RNA Research and Splicing
- Gastroesophageal reflux and treatments
Fourth Hospital of Hebei Medical University
2016-2025
Hebei Medical University
2016-2025
Hospital of Hebei Province
2015-2023
Sun Yat-sen University
2022-2023
London Cancer
2022
London School of Hygiene & Tropical Medicine
2022
University College London Hospitals NHS Foundation Trust
2022
University College London
2022
Eastern Hepatobiliary Surgery Hospital
2020-2021
Second Military Medical University
2020-2021
From 2003 to 2005, standardised 5-year cancer survival in China was much lower than developed countries and varied substantially by geographical area. Monitoring population-level is crucial the understanding of overall effectiveness care. We therefore aimed investigate statistics for people with between 2015.
Limited population‐based cancer registry data available in China until now has hampered efforts to inform control policy. Following extensive improve the systematic surveillance this country, we report on largest pooled analysis of survival date. Of 21 registries, from 17 registries ( n = 138,852 records) were included final analysis. Cases diagnosed 2003–2005 and followed end 2010. Age‐standardized relative was calculated using region‐specific life tables for all cancers combined 26...
Purpose There are no global screening recommendations for esophageal squamous cell carcinoma (ESCC). Endoscopic has been investigated in areas of high incidence China since the 1970s. This study aimed to evaluate whether an endoscopic and intervention program could reduce mortality caused by ESCC. Methods Residents age 40 69 years were recruited from communities with rates Fourteen villages selected as communities. Ten not geographically adjacent comparison. Participants group screened once...
Esophageal cancer incident cases and deaths in 2009 were retrieved from national database of population based registry to describe esophageal burden registration areas.In 2012, 104 population-based registries reported incidence mortality data Chinese National Central Cancer Registry. Total 72 registries' met the criteria be pooled analyzed. The crude rates calculated by age, gender area. China sensus 1982 Segi's world applied for age standardized rates.The ranked fifth all sites with rate...
// Jin-Hu Fan 1, * , Yu-Qing Zhang Su-Sheng Shi 2 Yuan-Jia Chen 3 Xing-Hua Yuan 4 Li-Ming Jiang 5 Shao-Ming Wang 1 Li Ma 6 Yu-Tong He 7 Chang-Yan Feng 8 Xi-Bin Sun 9 Qing Liu 10 Katrina Deloso 11 Yihebali Chi 12 and You-Lin Qiao Department of Cancer Epidemiology, Hospital, Chinese Academy Medical Sciences & Peking Union College Pathology, Gastroenterology, College, Abdominal Surgery, Radiology, Dalian University Hebei Registry, the Fourth hospital medical university Nutrition, Chongqing...
Abstract Objective This study aimed to investigate the potential determining epidemiological and clinical risk factors affecting survival of esophageal cancer (EC) patients across multiple hospitals in China. Methods was a multicenter comprising newly diagnosed EC cases from Beijing, Hebei, Henan, Hubei, Zhejiang, Guangdong Province Their baseline characteristics treatment methods data were collected their medical records. The EpiData software used for quality control. Kaplan‐Meier method...
Using data from cancer registries to estimate laryngeal incidence and mortality in China, 2015.Data submitted 501 were checked evaluated according the criteria of quality control 368 registries' qualified for final analysis. Data stratified by area (urban/rural), sex, age group combined with national population 2015. China census 2000 Segi's used age-standardized.The percentage cases morphological verified (MV%) was 74.18%. The death certificate-only (DCO%) 2.10%. And (M/I) ratio 0.55. About...
Incidence rates have risen for gastric cardia adenocarcinoma, whereas remained stable esophageal squamous cell carcinoma in many western countries. The aim of this study was to describe and analyze trends incidence cancer Cixian county, which is one the high-risk areas China as well world. data were obtained from Cancer Registry, a population-based registry. All checked analyzed using SPSS 11.5. Between years 1988 2003 there 11 183 cases county. age-standardized rate 168.55 per 100 000. In...
Abstract To explore the epidemiological characteristics and prognosis of lung cancer in patients aged under 45 years old northern China. The population-based database about cases 45y selected form Hebei Provincial Cancer Registry Center from 2010–2015. Mortality data young death 1973 to 1975, 1990 1992, 2004 2005 were extracted national retrospective survey death. rates calculated by mortality above this analysis. Consecutive, 954 non-selected younger (< years) 2261 older (≥ with...
Cutaneous squamous cell carcinoma (cSCC) is the second most frequent of keratinocyte-derived malignancies with actinic keratosis (AK) as a precancerous lesion. To comprehensively delineate underlying mechanisms for whole progression from normal skin to AK invasive cSCC, we performed single-cell RNA sequencing (scRNA-seq) acquire transcriptomes 138,982 cells 13 samples six patients including AK, in situ (SCCIS), and their matched tissues, covering comprehensive clinical courses cSCC. We...
Pulmonary nodules are the main manifestations of early lung cancer. Non-small cell cancer is most common histological type cancer, and classification non-small adenocarcinoma. The present study aimed to analyze differentially expressed genes between patients with benign malignant pulmonary nodules, identify potential therapeutic targets for Sequencing data nodule samples no were obtained from National Center Biotechnology Information Gene Expression Omnibus GSE135304 dataset. Differential...
Objective: With the aggravation of population aging, burden malignant tumors in elderly is becoming more and heavy. This study aims to analyze incidence mortality Hebei Province past decade. Methods: The data people aged ≥60 years old 38 cancer registration areas from 2011 2020 were collected, analyzed by gender, urban rural areas, age groups. standardized rates calculated using 2000 Chinese census Segi's world population. trend was Joinpoint model average annual percent change (AAPC)....
The existing gastric cancer (GC) risk prediction models based on biomarkers are limited. This study aims to identify new promising for GC develop a model effective assessment, screening, and early diagnosis. was conducted utilizing large combined cohort upper gastrointestinal that established in Hebei Province, China. General macro factors, Helicobacter pylori (H.pylori) infection status, protein were collected through questionnaire surveys laboratory tests. Novel explored using...
National cancer incidence data were utilized to analyze trends in esophageal China order provide basic information for making control strategy. We retrieved and re-sorted valid from Central Cancer Registry Database over 20 years period 1989 2008. Crude age-standardized rates calculated analysis, with annual percent change estimated by Joinpoint software long term trend analysis. The crude rate of was found have remained relatively stable both urban rural areas the year period. Age...
To analyze the incidence and mortality rates of esophagus cancer in China from 2008 to 2012.Incident cases were retrieved National Central Cancer Registry (NCCR) database collecting 135 registries during 2008-2012. The calculated by area (urban/rural), region (eastern, middle, western), gender age group (0, 1-4, 5-84 5 years 85+ years). census 2000 Segi's world population applied for age-standardized rates. Joinpoint model was used time-trend analysis.The crude rate 22.57/100,000. standard...
Despite having one of the highest mortality rates all cancers, risk factors pancreatic cancer remain unclear. We assessed in China.A case-control study design was conducted using data from four hospital-based registries (Henan Provincial Cancer Hospital, Beijing Hebei and Hospital Chinese Academy Medical Sciences). Controls were equally matched selected family members non-pancreatic patients same hospitals. Face-to-face interviews by trained staff questionnaires. Conditional logistic...
Background and Objective: Compared with tissue biopsy, liquid biopsy is the most preferable non-invasive promising method in personalized medicine, although it has many limitations isolating circulating tumor cells (CTC). Lung cancer associated mortality drastically increased due to a shortfall of early-stage detection, which remains challenge. Herein, we aimed detect lung at an using CellCollector device. Methods: 39,627 volunteers underwent low-dose computed tomography; 2508 cases...
Circulating tumor cells (CTCs) are promising biomarkers for clinical application. Cancer screening with Low-Dose Computed Tomography (LDCT) and CTC detections in pulmonary nodule patients has never been reported. The aim of this study was to explore the effectiveness combined methods screen lung cancer. Out 8313 volunteers screened by LDCT, 32 ground-glass nodules (GGNs) 19 healthy were randomly selected. Meanwhile, 15 cancer also enrolled. CellCollector, a new capturing device, applied CTCs...
Worldwide breast cancer incidence correlates with socioeconomic status and increases in parallel westernization, however urban-rural disparity trends have not been adequately investigated China.The age standardized rate (ASR) of female by population-based registration was compared between urban Shijiazhuang city rural Shexian County relation to status. The increasing trend from 2000-2015 examined using Joinpoint analysis the correlation gross domestic product (GDP) per capita analyzed.In...
Objective To study urban–rural disparity in colorectal cancer incidence and the increasing trend relation to rapid socioeconomic development urbanization China. Methods We compared age-standardized rates (ASRs) of between rural urban areas China 2012 analyzed Shexian County for 2000–2015 using population-based tumor registration data collected Shijiazhuang city (2012) (2000–2015). Results The ASRs (urban) were considerably higher than (rural) both men (22.8 vs. 11.9/100,000) women (15.0...