A5063912769- Air Quality and Health Impacts
- Climate Change and Health Impacts
- Energy and Environment Impacts
- Chronic Obstructive Pulmonary Disease (COPD) Research
- Noise Effects and Management
- Occupational exposure and asthma
- Occupational and environmental lung diseases
- Asthma and respiratory diseases
- Indoor Air Quality and Microbial Exposure
- Air Quality Monitoring and Forecasting
- Occupational Health and Safety Research
- Interstitial Lung Diseases and Idiopathic Pulmonary Fibrosis
- Fire effects on ecosystems
- Inhalation and Respiratory Drug Delivery
- Allergic Rhinitis and Sensitization
- Medical and Biological Ozone Research
- Atmospheric chemistry and aerosols
- Smoking Behavior and Cessation
- Arsenic contamination and mitigation
- Child Nutrition and Water Access
- Energy, Environment, and Transportation Policies
- Sarcoidosis and Beryllium Toxicity Research
- Antioxidant Activity and Oxidative Stress
- Occupational Health and Performance
- Respiratory Support and Mechanisms
University of California, Berkeley
2016-2025
University of California, San Francisco
2016-2025
Berkeley Public Health Division
2015-2025
California Air Resources Board
2012-2024
California State University, Fresno
2023
American Thoracic Society
2012-2021
Berkeley College
2005-2021
San Francisco General Hospital
1998-2020
Center for Environmental Health
1991-2020
University of California System
2015-2020
Lung cancer and cardiovascular disease are major causes of death in the United States. It has been proposed that carotenoids retinoids agents may prevent these disorders.
Estimating the burden of disease attributable to long-term exposure fine particulate matter (PM2.5) in ambient air requires knowledge both shape and magnitude relative risk (RR) function. However, adequate direct evidence identify mortality RR functions at high concentrations observed many places world is lacking.We developed over entire global range for causes adults: ischemic heart (IHD), cerebrovascular (stroke), chronic obstructive pulmonary (COPD), lung cancer (LC). We also incidence...
Background : Evidence has accumulated from observational studies that people eating more fruits and vegetables, which are rich in β-carotene (a violet to yellow plant pigment acts as an antioxidant can be converted vitamin A by enzymes the intestinal wall liver) retinol (an alcohol chemical form of A), having higher serum concentrations had lower rates lung cancer. The Beta-Carotene Retinol Efficacy Trial (CARET) tested combination 30 mg 25 000 IU retinyl palmitate (vitamin A) taken daily...
In the Comparative Risk Assessment (CRA) done as part of Global Burden Disease project (GBD-2010), global and regional burdens household air pollution (HAP) due to use solid cookfuels, were estimated along with 60+ other risk factors. This article describes how HAP CRA was framed; exposures modeled; diseases judged have sufficient evidence for inclusion; meta-analyses exposure-response modeling estimate relative risks. We explore relationships factors: ambient pollution, smoking, secondhand...
We explored the relationship between social isolation and mortality in a nationally representative US sample compared predictive power of with that traditional clinical risk factors.We used data on 16,849 adults from Third National Health Nutrition Examination Survey Death Index. Predictor variables were 4 factors composite index. Comparison predictors included smoking, obesity, elevated blood pressure, high cholesterol. Unadjusted Kaplan-Meier tables Cox proportional hazards regression...
The American Thoracic Society has previously published statements on what constitutes an adverse effect health of air pollution in 1985 and 2000. We set out to update broaden these past that focused primarily effects the respiratory system. Since then, many studies have documented other organ systems, such as cardiovascular central nervous systems. In addition, new biomarkers been developed applied studies. This current report seeks integrate latest science into a general framework for...
Background: The Beta-Carotene and Retinol Efficacy Trial (CARET) tested the effect of daily β-carotene (30 mg) retinyl palmitate (25 000 IU) on incidence lung cancer, other cancers, death in 18 314 participants who were at high risk for cancer because a history smoking or asbestos exposure. CARET was stopped ahead schedule January 1996 randomly assigned to receive active intervention found have 28% increase 17% higher rate cardiovascular disease mortality compared with placebo group....
BackgroundWHO estimates exposure to air pollution from cooking with solid fuels is associated over 4 million premature deaths worldwide every year including half a children under the age of 5 years pneumonia. We hypothesised that replacing open fires cleaner burning biomass-fuelled cookstoves would reduce pneumonia incidence in young children.MethodsWe did community-level cluster randomised controlled trial compare effects cookstove intervention continuation fire on living two rural...
Asthma disproportionately affects communities of colour in the USA, but underlying factors for this remain poorly understood. In study, we assess role historical redlining as outlined security maps created by Home Owners' Loan Corporation (HOLC), discriminatory practice categorising neighbourhoods on basis perceived mortgage investment risk, burden asthma these neighbourhoods.We did an ecological study HOLC risk grades and exacerbations California using available following eight cities:...
Acute exacerbations of idiopathic pulmonary fibrosis are associated with high mortality and unknown cause. The effect air pollution on interstitial lung disease is unknown. This study aims to define the association exposure acute exacerbation fibrosis. Patients corresponding data were identified from a longitudinal cohort. Air exposures assigned each patient for ozone, nitrogen dioxide, particulate matter, sulfur dioxide carbon monoxide based geo-coded residential addresses. Cox proportional...
Air pollution is a known asthma trigger and has been associated with short-term symptoms, airway inflammation, decreased lung function, reduced response to rescue medications.To assess causal relationship between air childhood using data that address temporality by estimating exposures before the development of establish generalizability association studying diverse racial/ethnic populations in different geographic regions.This study included Latino (n = 3,343) African American 977)...
Estimating population exposure to particulate matter during wildfires can be difficult because of insufficient monitoring data capture the spatiotemporal variability smoke plumes. Chemical transport models (CTMs) and satellite retrievals provide that may useful in predicting PM2.5 wildfires. We estimated concentrations 2008 northern California using 10-fold cross-validation (CV) select an optimal prediction model from a set 11 statistical algorithms 29 predictor variables. The variables...