Howard M. Kipen

ORCID: 0000-0001-6608-3126
Publications
Citations
Views
---
Saved
---
About
Contact & Profiles
Research Areas
  • Air Quality and Health Impacts
  • Air Quality Monitoring and Forecasting
  • Climate Change and Health Impacts
  • Fibromyalgia and Chronic Fatigue Syndrome Research
  • Indoor Air Quality and Microbial Exposure
  • Noise Effects and Management
  • Vehicle emissions and performance
  • Occupational and environmental lung diseases
  • Occupational Health and Safety Research
  • Occupational exposure and asthma
  • Energy and Environment Impacts
  • Occupational Health and Performance
  • Chemical Safety and Risk Management
  • Chronic Obstructive Pulmonary Disease (COPD) Research
  • Spaceflight effects on biology
  • Atmospheric chemistry and aerosols
  • Asthma and respiratory diseases
  • Posttraumatic Stress Disorder Research
  • Olfactory and Sensory Function Studies
  • Health, psychology, and well-being
  • Musculoskeletal pain and rehabilitation
  • Carcinogens and Genotoxicity Assessment
  • History and advancements in chemistry
  • Neonatal Respiratory Health Research
  • COVID-19 and healthcare impacts

Environmental and Occupational Health Sciences Institute
2015-2025

Rutgers Sexual and Reproductive Health and Rights
2003-2025

Rutgers, The State University of New Jersey
2015-2024

National Institute of Environmental Health Sciences
2004-2018

National Institute for Occupational Safety and Health
2018

Orszagos Kornyezetegeszsegugyi Intezet
2018

Merck & Co., Inc., Rahway, NJ, USA (United States)
2018

Icahn School of Medicine at Mount Sinai
1986-2018

Johnson University
2006-2015

Reed Medical (United Kingdom)
2015

The American Thoracic Society has previously published statements on what constitutes an adverse effect health of air pollution in 1985 and 2000. We set out to update broaden these past that focused primarily effects the respiratory system. Since then, many studies have documented other organ systems, such as cardiovascular central nervous systems. In addition, new biomarkers been developed applied studies. This current report seeks integrate latest science into a general framework for...

10.1183/13993003.00419-2016 article EN European Respiratory Journal 2016-12-19

<h3>Context</h3>Air pollution is a risk factor for cardiovascular diseases (CVD), but the underlying biological mechanisms are not well understood.<h3>Objective</h3>To determine whether markers related to CVD pathophysiological pathways (biomarkers systemic inflammation and thrombosis, heart rate, blood pressure) sensitive changes in air pollution.<h3>Design, Setting, Participants</h3>Using quasi-experimental opportunity offered by greatly restricted emissions during Beijing Olympics, we...

10.1001/jama.2012.3488 article EN JAMA 2012-05-16

Rationale: Unprecedented pollution control actions during the Beijing Olympics provided a quasi-experimental opportunity to examine biologic responses drastic changes in air levels.Objectives: To determine whether levels of biomarkers reflecting pulmonary inflammation and systemic oxidative stress were associated with healthy young adults.Methods: We measured fractional exhaled nitric oxide, number breath condensate markers (H+, nitrite, nitrate, 8-isoprostane), urinary...

10.1164/rccm.201205-0850oc article EN American Journal of Respiratory and Critical Care Medicine 2012-08-31

Using a quasi-experimental opportunity offered by greatly restricted air pollution emissions during the Beijing Olympics compared to before and after Olympics, we conducted current study compare ultrafine particles (UFPs) fine (PM2.5) in their associations with biomarkers reflecting multiple pathophysiological pathways linking exposure cardiorespiratory events. Number concentrations of (13.0-764.7 nm) mass PM2.5 were measured at two locations within 9 km from residence workplace 125...

10.1021/es5006016 article EN publisher-specific-oa Environmental Science & Technology 2014-03-25

This study examines the primary and secondary products resulting from reactions initiated by adding ozone to complex mixtures of volatile organic compounds (VOC). The were representative species typically found indoors, but concentrations tended be higher than normal indoor levels. Each 4-h experiment was conducted in a controlled environmental facility (CEF, 25 m3) ventilated at ∼1.8 h-1. mixture investigated included 23 VOC (no O3), O3/23 VOC, O3/21 d-limonene or α-pinene), O3/terpene only...

10.1021/es026231i article EN Environmental Science & Technology 2003-03-21

The present study had two objectives: 1) to determine the characteristics that differentiated subjects with multiple chemical sensitivities (MCS), (CS), and chronic fatigue syndrome (CFS); 2) evaluate psychiatric neuropsychological complaints of these groups relative normal controls. A cross-sectional comparison was made following matched for age, sex, education: patients whose low level exposures began a defined exposure (MCS; N = 23); chemicals without clear date onset (CS; 13); 3) meeting...

10.1097/00006842-199601000-00007 article EN Psychosomatic Medicine 1996-01-01

This study was undertaken to determine the relation between radiographic and histological manifestations of pulmonary asbestosis (interstitial fibrosis) in insulation workers who had died lung cancer. Of 450 confirmed deaths from cancer a chest radiograph suitable for determining evidence pneumoconiosis obtained 219. these cases, 138 also tissue specimen submitted that extent fibrosis. There significant albeit limited correlation findings (r = 0.27, p less than 0.0013). All cases parenchymal...

10.1136/oem.44.2.96 article EN Occupational and Environmental Medicine 1987-02-01

In our present study we tested the health effects among women of controlled exposures to volatile organic compounds (VOCs), with and without ozone (O3), psychological stress. Each subject was exposed following three conditions at 1-week intervals (within-subject factor): VOCs (26 mg/m3), + O3 mg/m3 40 ppb), ambient air a 1-min spike (2.5 mg/m3). As between-subjects factor, half subjects were randomly assigned perform stressor. Subjects 130 healthy (mean age, 27.2 years; mean education, 15.2...

10.1289/ehp.8132 article EN public-domain Environmental Health Perspectives 2005-07-21

We present a portable non-invasive approach for measuring indicators of inflammation and oxidative stress in the respiratory tract by quantifying biomarker exhaled breath condensate (EBC). discuss fabrication characterization miniaturized electrochemical sensor detecting nitrite content EBC using reduced graphene oxide. The has been demonstrated to be promising tract, particularly asthma. utilized unique properties oxide (rGO); specifically, material is resilient corrosion while exhibiting...

10.1038/micronano.2017.22 article EN cc-by Microsystems & Nanoengineering 2017-05-22

Individuals with COVID-19 who do not require hospitalization are instructed to self-isolate in their residences. Due high secondary infection rates household members, there is a need understand airborne transmission of SARS-CoV-2 within We report the first naturalistic intervention study suggesting reduction such risk using portable air cleaners (PACs) HEPA filters. Seventeen individuals newly diagnosed completed this single-blind, crossover, randomized study. Total and size-fractionated...

10.1111/ina.13029 article EN Indoor Air 2022-04-01

This study evaluated neuropsychological effects due to chronic organophosphate use among farmers with no history of acute poisoning. Fifty-seven male tree fruit (exposed) were compared 42 age-matched cranberry/blueberry growers and hardware store owners (unexposed). Univariate analyses covariance (reading test as covariate) comparing exposed unexposed subjects revealed significantly slower reaction time. No other significant differences noted on tests concentration, visuomotor skills,...

10.1002/(sici)1097-0274(199711)32:5<487::aid-ajim8>3.3.co;2-j article EN American Journal of Industrial Medicine 1997-11-01

Fuel additives incorporating nanosized ceria have been increasingly used in diesel engines as combustion promoters. However, few studies assessed the impact of these nanotechnology-based on pollutant emissions. Here, we systematically compare emission rates particulate and gaseous pollutants from a single-cylinder, four-cycle engine using fuel mixes containing nanoceria varying concentrations. The test fuels were made by adding different amounts commercial additive Envirox into an...

10.1021/es402140u article EN Environmental Science & Technology 2013-10-21

Abstract Epidemiological studies suggest that chronic exposure to air pollution increases susceptibility respiratory infections, including tuberculosis in humans. A possible link between particulate pollutant and antimycobacterial immunity has not been explored human primary immune cells. We hypothesized diesel exhaust particles (DEP), a major component of urban fine matter, suppresses effector cell functions by modulating TLR-signaling pathways NF-κB activation. show DEP H37Ra, an avirulent...

10.4049/jimmunol.1101380 article EN The Journal of Immunology 2012-02-16

For many individuals, daily commuting activities on roadways account for a substantial proportion of total exposure, as well peak-level exposures, to traffic-related air pollutants (TRAPS) including ultrafine particles, but the health impacts these exposures are not well-understood. We sought determine if exposure TRAPs particles during causes acute oxidative stress in respiratory tract or changes heart rate variability (HRV), measure autonomic activity.We conducted randomized, cross-over...

10.1186/s12989-014-0045-5 article EN cc-by Particle and Fibre Toxicology 2014-10-31

The etiology of adult-onset asthma is incompletely understood. Highintensity exposure to irritants one accepted risk factor and such cases are termed Reactive Airways Dysfunction Syndrome. contribution less intense acute remains be clarified. We report on 10 nonsensitization in settings noticeable but distinctly “tolerable” levels inhalation irritants. This series represent 31% verified seen our environmental occupational medicine referral clinic over a 5-year period. believe further...

10.1097/00043764-199410000-00017 article EN Journal of Occupational and Environmental Medicine 1994-10-01

Because no information exists on the prevalence of chemical sensitivity syndromes such as multiple sensitivities, a questionnaire for use in population studies was developed and tested to assess presence or absence sensitivity. Seven hundred five individuals attending clinics answered asking whether each 122 common substances caused symptoms. Results showed that patients with sensitivities asthma had average total scores were significantly different from other those diagnostic categories....

10.2105/ajph.85.4.574 article EN American Journal of Public Health 1995-04-01
Coming Soon ...